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Solid Phase Extraction (SPE)

Solid-phase extraction (SPE) is a technique designed for rapid sample preparation and purification prior chromatographic analysis. You can optimize your SPE protocols by using SiliCycle SiliaPrep™ and SiliaPrepX™ SPE Cartridges and Well Plates.

For your convenience, SiliaPrep and SiliaPrepX are available in different formats; cartridges (SiliaPrep SPE Cartridges), and well plates (SiliaPrep 96 Well Plates) with various sorbents (SiliaFlash® andSiliaBond®), and bed weight (up to 20 grams). The well plates are used in high throughput combinatorial chemistry, drug discovery and screening, and metabolism pharmacokinetics applications and for automated method as multiprobe approach.

By using SiliaPrep and SiliaPrepX products you will generate higher purity samples and reduce the number of false positives in your screening, resulting in higher quality data. All the SiliaPrep are packed with sorbents based on the fines-free SiliaFlash silica gel.

APPLICATION NOTES

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  1. SiliaPrep™ SPE Cartridges Silica

    SiliaPrep™ SPE Cartridges Silica

    SiliaPrep Silica is the most polar sorbent presenting a slightly acidic character used to extract various compounds from non-polar solvents using hydrogen bonding. Efficient sorbent for the separation of analytes with similar structures and for removing the baseline noise from organic samples.

  2. SiliaPrep™ SPE Cartridges Amine (WAX)

    SiliaPrep™ SPE Cartridges Amine (WAX)

    SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.

  3. SiliaPrep™ SPE Cartridges Amine nec (WAX)

    SiliaPrep™ SPE Cartridges Amine nec (WAX)

    SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.

  4. SiliaPrep™ SPE Cartridges Carboxylic Acid (WCX)

    SiliaPrep™ SPE Cartridges Carboxylic Acid (WCX)

    SiliaPrep Carboxilic Acid is a weak cation exchanger sorbent (WCX) used to extract strong basics compounds.

  5. SiliaPrep™ SPE Cartridges Carboxylic Acid nec (WCX)

    SiliaPrep™ SPE Cartridges Carboxylic Acid nec (WCX)

    SiliaPrep Carboxilic Acid nec is a weak cation exchanger sorbent (WCX) used to extract strong basics compounds.

  6. SiliaPrep™ SPE Cartridges Cyano

    SiliaPrep™ SPE Cartridges Cyano

    SiliaPrep Cyano is a moderate polar sorbent used as reversed-phase (less hydrophobic than C18 and C8 phases) and normal phase (less polar compared to silica) to extract acidic, neutral, basic compounds from aqueous solutions.

  7. SiliaPrep™ SPE Cartridges Cyano nec

    SiliaPrep™ SPE Cartridges Cyano nec

    SiliaPrep Cyano nec is a moderate polar sorbent used as reversed-phase (less hydrophobic than C18 and C8 phases) and normal phase (less polar compared to silica) to ectract acidic, neutral, basic compounds from aqueous solutions.

  8. SiliaPrep™ SPE Cartridges Diol

    SiliaPrep™ SPE Cartridges Diol

    SiliaPrep Diol nec is a moderate polar sorbent presenting neutral character used to extract polar compounds from non-polar solvents, structural isomers. Alternative to silica when the acidic character is problematic.

  9. SiliaPrep™ SPE Cartridges C1

    SiliaPrep™ SPE Cartridges C1

    SiliaPrep C1 is a non-polar sorbent and presents a mederate hydrophobicity. This phase is used to extract extremely non-polar compounds.

  10. SiliaPrep™ SPE Cartridges C2

    SiliaPrep™ SPE Cartridges C2

    SiliaPrep C2 is a non-polar sorbent and presents a moderate hydrophobicity. This phase is used to extract extremely non-polar compounds.

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Filter By
Chromatographic Mode
  1. Reversed Phases (6)
Support Backbone
  1. Polymeric Resins (11)
Type of Column
  1. Narrow Bore Columns (2)
  2. Analytical Columns (4)
USP Code
  1. L1 (4)
Metal to Remove
Cadmium (Cd)
  1. Preferred Scavengers (2)
  2. Scavenge (3)
Cobalt (Co)
  1. Scavenge (6)
Chromium (Cr)
  1. Preferred Scavengers (5)
Copper (Cu)
  1. Scavenge (6)
Iron (Fe)
  1. Scavenge (6)
Mercury (Hg)
  1. Scavenge (4)
Iridium (Ir)
  1. Preferred Scavengers (1)
Nickel (Ni)
  1. Preferred Scavengers (1)
  2. Scavenge (3)
Osmium (Os)
  1. Preferred Scavengers (1)
Lead (Pb)
  1. Preferred Scavengers (1)
  2. Scavenge (4)
Palladium (Pd-2+)
  1. Preferred Scavengers (4)
  2. Scavenge (2)
Palladium (Pd-0)
  1. Preferred Scavengers (4)
Platinum (Pt)
  1. Preferred Scavengers (6)
Rhodium (Rh-1+)
  1. Preferred Scavengers (3)
Rhodium (Rh-2+)
  1. Preferred Scavengers (3)
Rhodium (Rh-3+)
  1. Preferred Scavengers (1)
Ruthenium (Ru-2+)
  1. Preferred Scavengers (1)
  2. Scavenge (3)
Scandium (Sc)
  1. Scavenge (1)
Tungsten (W)
  1. Scavenge (5)
Zinc (Zn)
  1. Scavenge (6)
Family / Formats
  1. SiliaChrom® (HPLC Columns) (6)
  2. SiliaPrep™ (SPE Cartridges) (98)
  3. SiliaPrepX™ (SPE Polymeric Cartridges) (10)
Phases
  1. Activated Carbon (1)
  2. Activated Carbon/Amine (WAX) (1)
  3. Activated Carbon/Diamine (PSA) (1)
  4. Alumina (3)
  5. Amine (4)
  6. C1 (1)
  7. C18 (18)
  8. C2 (3)
  9. C4 (3)
  10. C8 (14)
  11. Carbonate (2)
  12. Carboxylic Acid (WCX) (4)
  13. CleanDRUG (1)
  14. CleanENVI (1)
  15. Cyano (4)
  16. Cyclohexyl (1)
  17. Diamine (2)
  18. Diethylamine (WAX-2) (2)
  19. Dimercaptotriazine (DMT) (1)
  20. Diol (2)
  21. dt C18 (3)
  22. DVB (2)
  23. Florisil (2)
  24. Fluorochrom (2)
  25. HLB (2)
  26. Pentafluorophenyl (2)
  27. Phenyl (2)
  28. Piperazine (1)
  29. Propylsulfonic Acid (SCX-2) (4)
  30. SAX (9)
  31. SCX (6)
  32. SCX-2 (7)
  33. Silica (2)
  34. TMA Acetate (5)
  35. TMA Chloride (SAX) (2)
  36. Tosic Acid (SCX) (4)
  37. Triamine (1)
  38. Tridecafluoro (2)
  39. WAX (1)
  40. WCX (4)
  41. XT C18 (3)
Pore Size
  1. 60 Å (103)
  2. 110 Å (2)
Endcapping
  1. Endcapped (91)
  2. Non-endcapped (31)
Cartridges Volume
  1. 1 mL (57)
  2. 2 mL (36)
  3. 3 mL (61)
  4. 6 mL (61)
  5. 12 mL (57)
  6. 25 mL (57)
Bed Weight
  1. 50 mg (92)
  2. 100 mg (93)
  3. 200 mg (58)
  4. 250 mg (3)
  5. 500 mg (61)
  6. 1 g (58)
  7. 2 g (58)
  8. 5 g (57)
Particle Size
  1. 40 µm (2)
  2. 85 µm (9)
  3. 40-63 µm (94)

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