Use Of SiliaCat TEMPO
Carbonyl groups are among the most important functional groups in organic chemistry and their introduction by the oxidation of alcohols is a process of major importance. SiliaCat® TEMPO is a catalyst for selective oxidation of primary and secondary alcohols to aldehydes and ketones respectively.
The major advantage of this reagent is the possibility to obtain good yields under mild conditions in the absence of toxic heavy metals. SiliaCat TEMPO can be use in stoechiometric amount as well as catalytically with a terminal oxidant allowing the closure of the catalytic cycle. SiliaCat TEMPO is provided under its nitroxyl form and must be transformed to its active form, the oxoammonium ion, prior to use.