Monomeric Vs. Polymeric C18
For the octadecylsilane stationary phase, SiliCycle proposes two different bonding types: the monomeric and the polymeric functionalized C18.
Silica surface possesses active silanols (Si-OH), which permits the modification of the surface chemistry by grafting silane moieties. This property permits the control of the surface polarity useful in separation techniques. In HPLC, two types of silane are grafted over the surface: chlorodimethylsilane or trichlorosilane.
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SiliaBond® C18 (23%)
SiliaBond® C18 (or C18) is the traditional matrix for reversed-phase chromatography. The high loading provides the highest degree of hydrophobicity commercially available. Considered as the least selective phase since it interacts with a wide range of organic molecules.
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SiliaBond® C18 nec (23%)
SiliaBond® C18 (or C18) is the traditional matrix for reversed-phase chromatography. The high loading provides the highest degree of hydrophobicity commercially available. Considered as the least selective phase since it interacts with a wide range of organic molecules. Also used in ion-pairing chromatography (non-endcapped) for the separation of biomolecules.
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SiliaBond® C18 (17%)
The SiliaBond® C18 17% BDS is the most efficient deactivated C18 reversed-phase. This versatile support is the best choice for your applications in reversed-phase chromatography. This chromatographic phase has been compared with different competitors and presents a better separation for basic compounds.
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SiliaBond® C18 nec (17%)
This non-endcapped version of the SiliaBond® C18 17% BDS, presents a perfect monolayer of dimethyloctadecylsilane and silanol functions. The hydrophilic/hydrophobic balance is permitting to use a mobile phase with a higher concentration of water and ion pairing conditions for separation of biomolecules.
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SiliaBond® C18 (11%)
SiliaBond® C18 11% is used as a reversed-phase chromatographic matrix when large hydrophobic molecules are too strongly retained on SiliaBond C18 with higher carbon content.
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SiliaSphere™ Spherical Silica Gels C18 mono
We offer the SiliaSphere™ C18 as a standard functionalized product in various pore sizes between 60 to 1000Å and in a wide range of particle size (1.8 to 15 µm).
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IMPAQ® Angular Silica Gel C18 mono
IMPAQ C18 is the traditional matrix for reversed-phase chromatography. The high loading provides the highest degree of hydrophobicity commercially available. Considered as the least selective phase since it interacts with a wide range of organic molecules.





