4. Scavenging Palladium Catalysts
A metal scavenging study using SiliaBond® Metal Scavengers products was conducted on various palladium catalysts (Pd(OAc)2, Pd(allyl)2Cl2, Pd2(dba)3, Pd(PPh3)4) commonly used in organic synthesis.
Various parameters were studied for their influence on the scavengers' robustness as well as to establish the best conditions to bring the level of metal down to an acceptable level for the pharmaceutical industry (i.e.: solvent, number of equivalents, temperature, and reaction time).
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.