7. Scavenging Ruthenium Catalysts
A metal scavenging study using SiliaBond® Metal Scavengers products was conducted on Grubbs, Hoveyda-Grubbs, TPAP and RuCl3 catalysts.
Various parameters were studied for their influence on the scavengers' robustness as well as to establish the best conditions to bring the level of metal down to an acceptable level for the pharmaceutical industry (i.e.: solvent, number of equivalents, temperature, and reaction time).
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SiliaMetS® Diamine
SiliaMetS® Diamine (Si-DIA) is a proven scavenger for metals and electrophiles. It scavenges acids, acid chlorides, anhydrides, aldehydes, isocyanates, and chloroformates as well as Pb, Ni, and Cd.
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