
Purification
SiliCycle offers interesting alternative to expedite a wide range of purification typically in the application domains of separation of products mixtures (chromatography) or with SiliaBond®Scavengers, functionalized silica gels designed to react and bind with excess reagents, metal complexes and/or by-products.
Application Notes
All available applications developed for purification purposes are listed below:
For metal removal refer to the following link for more information
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SiliaMetS® Thiol
SiliaMetS® Thiol (Si-Thiol) is a robust metal scavenger for a variety of metals including Pd, Pt, Cu, Ag and Pb under a wide range of conditions. It has been used in pharmaceutical processes up to the pilot plant scale. It is our most versatile metal scavenger and is the preferred metal scavenger for Pd(II), Cu, Ag, and Hg.
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SiliaMetS® Thiourea
SiliaMetS® Thiourea (Si-THU) is a versatile metal scavenger for all forms of palladium and is widely used in the pharmaceutical industry. It works particularly well in organic solvents. It can also be used to scavenge Ag, Pt, Ru, Rh and Hg. Once complexed with a transition metal, it has been reported as being an effective catalyst.
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SiliaMetS® Dimercaptotriazine (DMT)
SiliaMetS® DMT (Si-DMT) is the silica bound equivalent of 2,4,6-trimercaptotriazine (trithiocyanuric acid). It is a versatile metal scavenger for a variety of metals including Cd, Co, Ni, Pd, Pt, Rh, and Ru under a wide range of conditions and the preferred metal scavenger for ruthenium catalysts.
TMT has been reported to efficiently remove palladium and heavy metals by precipitation. Unfortunately, its solubility in organic solvents causes problem. SiliaMetS DMT solves this issue and almost all solvents can now be used.
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SiliaSep™ Flash Cartridges Thiol
SiliaSep flash thiol cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Thiourea
SiliaSep flash thiourea cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Dimercaptotriazine (DMT)
SiliaSep flash DMT cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges - Open Top (OT) Thiol
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
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SiliaPrep™ SPE Cartridges Thiol
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.
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SiliaPrep™ SPE Cartridges Thiourea
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.
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SiliaPrep™ SPE Cartridges Dimercaptotriazine (DMT)
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.





