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Use Of SiliaBond® Carbonate

SiliaBond® Carbonate (or Si-CO3) is the silica bound equivalent of tetramethylammonium carbonate. It can be used as a general base to quench a reaction, to free base amine hydrochlorides and to scavenge acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions. SiliaBond Carbonate is also very efficient at scavenging boronic acids: 99% of phenylboronic acid is removed with 1 equivalent of Si-CO3 in DCM at RT, after 1 h.

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  1. SiliaBond® Carbonate

    SiliaBond® Carbonate

    SiliaBond® Carbonate (Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.

  2. SiliaPrep™ SPE Cartridges Carbonate

    SiliaPrep™ SPE Cartridges Carbonate

    SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.

  3. SiliaPrep™ 96 Well Plates Carbonate

    SiliaPrep™ 96 Well Plates Carbonate


    Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
  4. SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate

    SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

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