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General Synthesis Applications

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  1. SiliaMetS® TAAcOH

    SiliaMetS® TAAcOH

    SiliaMetS® TAAcOH (SiliaMetS Triaminetetraacetic Acid) is a silica bound metal scavenger for Pd(0), Ni(0) and Cu. It is the supported version of EDTA in its free form. It is an effective scavenger for metals in low or zero oxidation states, which includes many of the most synthetically useful catalysts such as tetrakis-(triphenylphosphine)palladium(0).

  2. SiliaMetS® TAAcONa

    SiliaMetS® TAAcONa

    SiliaMetS® TAAcONa or (or SiliaMetS Triaminetetraacetate, sodium salt) is a silica bound metal scavenger for Pd(II), Ni(II) and Cu. It is the supported version of EDTA in its sodium salt form. It is an effective scavenger for metals in higher oxidation state, 2+ or higher.

  3. SiliaBond® Pyridinium Chlorochromate nec (PCC)

    SiliaBond® Pyridinium Chlorochromate nec (PCC)

    SiliaBond® Pyridinium Chlorochromate (Si-PCC) is used for the general oxidation of alcohols to carbonyl compounds, selective oxidation of allylic and benzylic alcohols, organometallic oxidation, oxidative transpositions, oxidative cleavages, allylic and benzylic oxidation and oxidative cyclizations.


  4. SiliaBond® Pyridinium Dichromate nec (PDC)

    SiliaBond® Pyridinium Dichromate nec (PDC)

    SiliaBond® Pyridinium Dichromate (Si-PDC) may be used as an alternative to Si-PCC in nucleoside and carbohydrate oxidation, particularly for fragile molecules. SiliaBond PDC can also be used in conjunction with tertbutylhydroperoxide for a variety of oxidative transformations.

  5. SiliaBond® Diphenylphosphine

    SiliaBond® Diphenylphosphine

    SiliaBond® Diphenylphosphine (Si-DPP) can be used as linker for catalyst immobilization such as tetrakis-(triphenylphosphine)palladium(0) for Suzuki coupling.

  6. SiliaBond® Propylsulfonic Acid nec (SCX-2)

    SiliaBond® Propylsulfonic Acid nec (SCX-2)

    Supported sulfonic acids such as SiliaBond® Propylsulfonic Acid (SiliaBond SCX-2) are in a class of strong acids widely used in different fields of synthetic organic chemistry. Their applications are well known and are used in a large number of settings going from drug discovery laboratories up to manufacturing processes. Among these applications, we denote their uses as acid catalysts, stationary phases for ion chromatography and basic impurity scavengers. Meanwhile, the most common use is probably as a strong cation exchanger (SCX) for the amine “Catch and Release” purification technique in SPE cartridges.

  7. SiliaBond® Tosic Acid nec (SCX)

    SiliaBond® Tosic Acid nec (SCX)

    SiliaBond® Tosic Acid (SiliaBond SCX, Si-TsOH) is a versatile bound strong acid with a pka <<1. It is widely used for the scavenging of amines and other basic functionalities, including weakly basic anilines, borohydrides, and metals such as Ni and Ag. It can also be used as an acid catalyst for organic reactions.6 Si-TsOH can serve as an alternative method to quench reactions instead of aqueous or organic soluble acids.


  8. SiliaBond® TMA Chloride nec (SAX)

    SiliaBond® TMA Chloride nec (SAX)

    SiliaBond® TMA Chloride (SiliaBond SAX, Si-TMACl) is mainly used as strong anion exchanger (SAX) in ion chromatography and ion exchange SPE. The function bears a positive charge across the whole pH range as well as in organic solvents.

  9. SiliaPrep™ SPE Cartridges Amine nec (WAX)

    SiliaPrep™ SPE Cartridges Amine nec (WAX)

    SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.

  10. SiliaPrep™ SPE Cartridges Carboxylic Acid nec (WCX)

    SiliaPrep™ SPE Cartridges Carboxylic Acid nec (WCX)

    SiliaPrep Carboxilic Acid nec is a weak cation exchanger sorbent (WCX) used to extract strong basics compounds.

  11. SiliaPrep™ SPE Cartridges TMA Chloride nec (SAX)

    SiliaPrep™ SPE Cartridges TMA Chloride nec (SAX)

    SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).

  12. SiliaPrep™ SPE Cartridges Tosic Acid nec (SCX)

    SiliaPrep™ SPE Cartridges Tosic Acid nec (SCX)

    SiliaPrep Tosic Acid is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.

  13. SiliaPrep™ SPE Cartridges Propylsulfonic Acid nec (SCX-2)

    SiliaPrep™ SPE Cartridges Propylsulfonic Acid nec (SCX-2)

    SiliaPrep Propylsulfonic Acid nec is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.

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Metal to Remove
Calcium (Ca)
  1. Preferred Scavengers (1)
Cadmium (Cd)
  1. Preferred Scavengers (2)
Cobalt (Co)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Chromium (Cr)
  1. Preferred Scavengers (1)
  2. Scavenge (2)
Cesium (Cs)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Copper (Cu)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Iron (Fe)
  1. Preferred Scavengers (1)
  2. Scavenge (2)
Mercury (Hg)
  1. Scavenge (1)
Iridium (Ir)
  1. Preferred Scavengers (1)
Lanthanum (La)
  1. Preferred Scavengers (1)
Lithium (Li)
  1. Preferred Scavengers (1)
Magnesium (Mg)
  1. Preferred Scavengers (1)
Nickel (Ni)
  1. Preferred Scavengers (2)
Osmium (Os)
  1. Preferred Scavengers (2)
Lead (Pb)
  1. Scavenge (1)
Palladium (Pd-2+)
  1. Scavenge (3)
Palladium (Pd-0)
  1. Scavenge (2)
Platinum (Pt)
  1. Preferred Scavengers (1)
Rhodium (Rh-1+)
  1. Preferred Scavengers (1)
  2. Scavenge (2)
Rhodium (Rh-2+)
  1. Preferred Scavengers (1)
  2. Scavenge (2)
Rhodium (Rh-3+)
  1. Preferred Scavengers (1)
Ruthenium (Ru-2+)
  1. Scavenge (1)
Scandium (Sc)
  1. Preferred Scavengers (2)
Tin (Sn)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Tungsten (W)
  1. Scavenge (1)
Zinc (Zn)
  1. Scavenge (2)
Family / Formats
  1. SiliaBond® (Functionalized Silicas) (6)
  2. SiliaMetS® (Metal Scavengers) (2)
  3. SiliaPrep™ (SPE Cartridges) (5)
Phases
  1. Amine (1)
  2. Carboxylic Acid (WCX) (1)
  3. Diphenylphosphine (1)
  4. Propylsulfonic Acid (SCX-2) (2)
  5. Pyridinium Chlorochromate (PCC) (1)
  6. Pyridinium Dichromate (PDC) (1)
  7. TAAcOH (1)
  8. TAAcONa (1)
  9. TMA Chloride (SAX) (2)
  10. Tosic Acid (SCX) (2)
Pore Size
  1. 60 Å (13)
Cartridges Volume
  1. 1 mL (5)
  2. 3 mL (5)
  3. 6 mL (5)
  4. 12 mL (5)
  5. 25 mL (5)
Bed Weight
  1. 50 mg (5)
  2. 100 mg (5)
  3. 200 mg (5)
  4. 500 mg (5)
  5. 1 g (5)
  6. 2 g (5)
  7. 5 g (5)
Particle Size
  1. 40-63 µm / 230-400 mesh (13)

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