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Synthesis

SiliCycle offers silica-based products that can be used in organic synthesis in replacement of homogeneous equivalents. In many cases, supported reagents have distinct advantages over their solution-phase counterparts, the biggest one being the ability to do multiple transformations in a single pot, the immobilization of toxic reagents, and increased selectivity. They are also suitable for use in batch reactions and in flow through applications.

Application Notes

All available applications developed for synthesis purposes are listed below:

General applications

  • Common Organic Reactions

For amide and ester synthesis refer to the following link for more information

Other applications

  • Use of SiliaBond Cyanoborohydride
  • Use of SiliaBond Carbonate
  • Difference Between SiliaBond PCC & PDC: When to Use Them?

SiliaBond Kit 

  • SiliaBond Reagents Kit for Microwave Applications

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  1. SiliaSep™ Flash Cartridges - Open Top (OT) Propylsulfonic Acid (SCX-2)

    SiliaSep™ Flash Cartridges - Open Top (OT) Propylsulfonic Acid (SCX-2)

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.

  2. SiliaSep™ Flash Cartridges - Open Top (OT) Tosic Acid (SCX)

    SiliaSep™ Flash Cartridges - Open Top (OT) Tosic Acid (SCX)

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.

  3. SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate

    SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

  4. SiliaSep™ Flash Cartridges - Open Top (OT) Thiol

    SiliaSep™ Flash Cartridges - Open Top (OT) Thiol

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

  5. SiliaSep™ Flash Cartridges - Open Top (OT) Amine

    SiliaSep™ Flash Cartridges - Open Top (OT) Amine

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

  6. SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec

    SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.

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