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Synthesis

SiliCycle offers silica-based products that can be used in organic synthesis in replacement of homogeneous equivalents. In many cases, supported reagents have distinct advantages over their solution-phase counterparts, the biggest one being the ability to do multiple transformations in a single pot, the immobilization of toxic reagents, and increased selectivity. They are also suitable for use in batch reactions and in flow through applications.

Application Notes

All available applications developed for synthesis purposes are listed below:

General applications

  • Common Organic Reactions

For amide and ester synthesis refer to the following link for more information

Other applications

  • Use of SiliaBond Cyanoborohydride
  • Use of SiliaBond Carbonate
  • Difference Between SiliaBond PCC & PDC: When to Use Them?

SiliaBond Kit 

  • SiliaBond Reagents Kit for Microwave Applications

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  1. SiliaBond® Propylsulfonic Acid nec (SCX-2)

    SiliaBond® Propylsulfonic Acid nec (SCX-2)

    Supported sulfonic acids such as SiliaBond® Propylsulfonic Acid (SiliaBond SCX-2) are in a class of strong acids widely used in different fields of synthetic organic chemistry. Their applications are well known and are used in a large number of settings going from drug discovery laboratories up to manufacturing processes. Among these applications, we denote their uses as acid catalysts, stationary phases for ion chromatography and basic impurity scavengers. Meanwhile, the most common use is probably as a strong cation exchanger (SCX) for the amine “Catch and Release” purification technique in SPE cartridges.

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