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Synthesis

SiliCycle offers silica-based products that can be used in organic synthesis in replacement of homogeneous equivalents. In many cases, supported reagents have distinct advantages over their solution-phase counterparts, the biggest one being the ability to do multiple transformations in a single pot, the immobilization of toxic reagents, and increased selectivity. They are also suitable for use in batch reactions and in flow through applications.

Application Notes

All available applications developed for synthesis purposes are listed below:

General applications

  • Common Organic Reactions

For amide and ester synthesis refer to the following link for more information

Other applications

  • Use of SiliaBond Cyanoborohydride
  • Use of SiliaBond Carbonate
  • Difference Between SiliaBond PCC & PDC: When to Use Them?

SiliaBond Kit 

  • SiliaBond Reagents Kit for Microwave Applications

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  1. SiliaPlate™ TLC Plates - Glass (G) CN

    SiliaPlate™ TLC Plates - Glass (G) CN

    Analytical SiliaPlate made with cyano-functionalized silica gel are available on glass backing.

  2. SiliaPlate™ TLC Plates - Glass (G) Diol

    SiliaPlate™ TLC Plates - Glass (G) Diol

    Analytical SiliaPlate made with diol-functionalized silica gel are available on glass backing.

  3. SiliaPlate™ TLC Plates - Aluminum (Al) Silica

    SiliaPlate™ TLC Plates - Aluminum (Al) Silica

    Standard normal phase Analytical SiliaPlate made with SiliaFlash® silica gel are available on aluminum backing. Different sizes available.

  4. SiliaMetS® TAAcONa

    SiliaMetS® TAAcONa

    SiliaMetS® TAAcONa or (or SiliaMetS Triaminetetraacetate, sodium salt) is a silica bound metal scavenger for Pd(II), Ni(II) and Cu. It is the supported version of EDTA in its sodium salt form. It is an effective scavenger for metals in higher oxidation state, 2+ or higher.

  5. SiliaPrep™ SPE Cartridges TMA Chloride nec (SAX)

    SiliaPrep™ SPE Cartridges TMA Chloride nec (SAX)

    SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).

  6. SiliaSep™ Flash Cartridges Amine

    SiliaSep™ Flash Cartridges Amine

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

    SiliaSep flash amine cartridges offer a superior alternative to the other cartridges available on the market.

  7. SiliaSep™ Flash Cartridges - Open Top (OT) Amine

    SiliaSep™ Flash Cartridges - Open Top (OT) Amine

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

  8. SiliaSep™ Flash Cartridges TMA Chloride (SAX)

    SiliaSep™ Flash Cartridges TMA Chloride (SAX)

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.

    SiliaSep flash TMA Chloride cartridges offer a superior alternative to the other cartridges available on the market.

  9. SiliaSep™ Flash Cartridges TMA Acetate nec

    SiliaSep™ Flash Cartridges TMA Acetate nec

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.

    SiliaSep flash TMA Acetate cartridges offer a superior alternative to the other cartridges available on the market.

  10. SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec

    SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec

    SiliaSep OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.

  11. SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine

    SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine

    SiliaSep BT flash cartridges are compatible with Biotage i-style compression modules.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

  12. SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine

    SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine

    SiliaSep BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

  13. SiliaPrep™ 96 Well Plates Carbonate

    SiliaPrep™ 96 Well Plates Carbonate


    Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.

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