Synthesis
SiliCycle offers silica-based products that can be used in organic synthesis in replacement of homogeneous equivalents. In many cases, supported reagents have distinct advantages over their solution-phase counterparts, the biggest one being the ability to do multiple transformations in a single pot, the immobilization of toxic reagents, and increased selectivity. They are also suitable for use in batch reactions and in flow through applications.
Application Notes
All available applications developed for synthesis purposes are listed below:
General applications
- Common Organic Reactions
For amide and ester synthesis refer to the following link for more information
Other applications
- Use of SiliaBond Cyanoborohydride
- Use of SiliaBond Carbonate
- Difference Between SiliaBond PCC & PDC: When to Use Them?
SiliaBond Kit
- SiliaBond Reagents Kit for Microwave Applications
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SiliaPlate™ TLC Plates - Glass (G) CN
Analytical SiliaPlate™ made with cyano-functionalized silica gel are available on glass backing.
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SiliaPlate™ TLC Plates - Glass (G) Diol
Analytical SiliaPlate™ made with diol-functionalized silica gel are available on glass backing.
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SiliaPlate™ TLC Plates - Aluminum (Al) Silica
Standard normal phase Analytical SiliaPlate™ made with SiliaFlash® silica gel are available on aluminum backing. Different sizes available.
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SiliaMetS® TAAcONa
SiliaMetS® TAAcONa or (or SiliaMetS Triaminetetraacetate, sodium salt) is a silica bound metal scavenger for Pd(II), Ni(II) and Cu. It is the supported version of EDTA in its sodium salt form. It is an effective scavenger for metals in higher oxidation state, 2+ or higher.
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SiliaPrep™ SPE Cartridges TMA Chloride nec (SAX)
SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).
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SiliaSep™ Flash Cartridges Amine
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
SiliaSep flash amine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges - Open Top (OT) Amine
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges TMA Chloride (SAX)
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.
SiliaSep flash TMA Chloride cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges TMA Acetate nec
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.
SiliaSep flash TMA Acetate cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaPrep™ 96 Well Plates Carbonate
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.






