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Synthesis

SiliCycle offers silica-based products that can be used in organic synthesis in replacement of homogeneous equivalents. In many cases, supported reagents have distinct advantages over their solution-phase counterparts, the biggest one being the ability to do multiple transformations in a single pot, the immobilization of toxic reagents, and increased selectivity. They are also suitable for use in batch reactions and in flow through applications.

Application Notes

All available applications developed for synthesis purposes are listed below:

General applications

  • Common Organic Reactions

For amide and ester synthesis refer to the following link for more information

Other applications

  • Use of SiliaBond Cyanoborohydride
  • Use of SiliaBond Carbonate
  • Difference Between SiliaBond PCC & PDC: When to Use Them?

SiliaBond Kit 

  • SiliaBond Reagents Kit for Microwave Applications

23 Item(s)

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  1. SiliaSep™ Flash Cartridges Tosic Acid (SCX)

    SiliaSep™ Flash Cartridges Tosic Acid (SCX)

    Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.

    SiliaSep flash propylsulfonic acid cartridges offer a superior alternative to the other cartridges available on the market.

  2. SiliaSep™ Flash Cartridges Propylsulfonic Acid (SCX-2)

    SiliaSep™ Flash Cartridges Propylsulfonic Acid (SCX-2)

    Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.

    SiliaSep flash propylsulfonic acid cartridges offer a superior alternative to the other cartridges available on the market..

  3. SiliaSep™ Flash Cartridges Triamine

    SiliaSep™ Flash Cartridges Triamine

    SiliaSep flash triamine cartridges offer a superior alternative to the other cartridges available on the market.

  4. SiliaSep™ Flash Cartridges Diamine

    SiliaSep™ Flash Cartridges Diamine

    SiliaSep flash diamine cartridges offer a superior alternative to the other cartridges available on the market.

  5. SiliaSep™ Flash Cartridges Thiol

    SiliaSep™ Flash Cartridges Thiol

    SiliaSep flash thiol cartridges offer a superior alternative to the other cartridges available on the market.

  6. SiliaSep™ Flash Cartridges TAAcOH

    SiliaSep™ Flash Cartridges TAAcOH

    SiliaSep flash TAAcOH cartridges offer a superior alternative to the other cartridges available on the market.

  7. SiliaSep™ Flash Cartridges TAAcONa

    SiliaSep™ Flash Cartridges TAAcONa

    SiliaSep flash TAAcONa cartridges offer a superior alternative to the other cartridges available on the market.

  8. SiliaSep™ Flash Cartridges Thiourea

    SiliaSep™ Flash Cartridges Thiourea

    SiliaSep flash thiourea cartridges offer a superior alternative to the other cartridges available on the market.

  9. SiliaSep™ Flash Cartridges Dimercaptotriazine (DMT)

    SiliaSep™ Flash Cartridges Dimercaptotriazine (DMT)

    SiliaSep flash DMT cartridges offer a superior alternative to the other cartridges available on the market.

  10. SiliaSep™ Flash Cartridges Cysteine

    SiliaSep™ Flash Cartridges Cysteine

    SiliaSep flash cysteine cartridges offer a superior alternative to the other cartridges available on the market .

  11. SiliaSep™ Flash Cartridges - Open Top (OT) Propylsulfonic Acid (SCX-2)

    SiliaSep™ Flash Cartridges - Open Top (OT) Propylsulfonic Acid (SCX-2)

    SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.

  12. SiliaSep™ Flash Cartridges - Open Top (OT) Tosic Acid (SCX)

    SiliaSep™ Flash Cartridges - Open Top (OT) Tosic Acid (SCX)

    SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.

  13. SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate

    SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate

    SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.

  14. SiliaSep™ Flash Cartridges - Open Top (OT) Thiol

    SiliaSep™ Flash Cartridges - Open Top (OT) Thiol

    SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.

  15. SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Propylsulfonic Acid (SCX-2)

    SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Propylsulfonic Acid (SCX-2)

    SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.

    Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.

  16. SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) SCX

    SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) SCX

    SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.

    Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.

  17. SiliaSep™ Flash Cartridges Amine

    SiliaSep™ Flash Cartridges Amine

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

    SiliaSep flash amine cartridges offer a superior alternative to the other cartridges available on the market.

  18. SiliaSep™ Flash Cartridges - Open Top (OT) Amine

    SiliaSep™ Flash Cartridges - Open Top (OT) Amine

    SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

  19. SiliaSep™ Flash Cartridges TMA Chloride (SAX)

    SiliaSep™ Flash Cartridges TMA Chloride (SAX)

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.

    SiliaSep flash TMA Chloride cartridges offer a superior alternative to the other cartridges available on the market.

  20. SiliaSep™ Flash Cartridges TMA Acetate nec

    SiliaSep™ Flash Cartridges TMA Acetate nec

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.

    SiliaSep flash TMA Acetate cartridges offer a superior alternative to the other cartridges available on the market.

  21. SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec

    SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec

    SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.

  22. SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine

    SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine

    SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

  23. SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine

    SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine

    SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.

23 Item(s)

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  1. X Family / Formats : SiliaSep™ (Flash Cartridges)
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Metal to Remove
Silver (Ag)
  1. Preferred Scavengers (2)
  2. Scavenge (1)
Calcium (Ca)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Cadmium (Cd)
  1. Preferred Scavengers (6)
  2. Scavenge (2)
Cobalt (Co)
  1. Preferred Scavengers (1)
  2. Scavenge (7)
Chromium (Cr)
  1. Preferred Scavengers (6)
  2. Scavenge (3)
Cesium (Cs)
  1. Preferred Scavengers (1)
  2. Scavenge (2)
Copper (Cu)
  1. Preferred Scavengers (1)
  2. Scavenge (11)
Iron (Fe)
  1. Preferred Scavengers (2)
  2. Scavenge (9)
Mercury (Hg)
  1. Preferred Scavengers (2)
  2. Scavenge (5)
Iridium (Ir)
  1. Preferred Scavengers (3)
  2. Scavenge (2)
Lanthanum (La)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Lithium (Li)
  1. Preferred Scavengers (1)
Magnesium (Mg)
  1. Preferred Scavengers (1)
  2. Scavenge (1)
Nickel (Ni)
  1. Preferred Scavengers (3)
  2. Scavenge (2)
Osmium (Os)
  1. Preferred Scavengers (6)
  2. Scavenge (1)
Lead (Pb)
  1. Preferred Scavengers (1)
  2. Scavenge (7)
Palladium (Pd-2+)
  1. Preferred Scavengers (6)
  2. Scavenge (7)
Palladium (Pd-0)
  1. Preferred Scavengers (6)
  2. Scavenge (3)
Platinum (Pt)
  1. Preferred Scavengers (7)
  2. Scavenge (1)
Rhodium (Rh-1+)
  1. Preferred Scavengers (5)
  2. Scavenge (6)
Rhodium (Rh-2+)
  1. Preferred Scavengers (5)
  2. Scavenge (6)
Rhodium (Rh-3+)
  1. Preferred Scavengers (2)
  2. Scavenge (3)
Ruthenium (Ru-2+)
  1. Preferred Scavengers (2)
  2. Scavenge (5)
Scandium (Sc)
  1. Preferred Scavengers (3)
  2. Scavenge (4)
Tin (Sn)
  1. Preferred Scavengers (2)
  2. Scavenge (4)
Tungsten (W)
  1. Scavenge (6)
Zinc (Zn)
  1. Scavenge (9)
Phases
  1. Amine (4)
  2. Carbonate (1)
  3. Cysteine (1)
  4. Diamine (1)
  5. Dimercaptotriazine (DMT) (1)
  6. Propylsulfonic Acid (SCX-2) (3)
  7. SCX (1)
  8. TAAcOH (1)
  9. TAAcONa (1)
  10. Thiol (2)
  11. Thiourea (1)
  12. TMA Acetate (2)
  13. TMA Chloride (SAX) (1)
  14. Tosic Acid (SCX) (2)
  15. Triamine (1)
Pore Size
  1. 60 Å (23)
Endcapping
  1. Endcapped (23)
Cartridges Volume
  1. 70 mL (6)
  2. 150 mL (6)
  3. 276 mL (6)
Bed Weight
  1. 4 g (15)
  2. 5 g (2)
  3. 8 g (2)
  4. 9 g (2)
  5. 10 g (6)
  6. 12 g (13)
  7. 15 g (6)
  8. 20 g (6)
  9. 25 g (19)
  10. 40 g (15)
  11. 45 g (2)
  12. 50 g (6)
  13. 70 g (6)
  14. 80 g (13)
  15. 90 g (4)
  16. 100 g (6)
  17. 120 g (13)
  18. 135 g (2)
  19. 200 g (2)
  20. 220 g (13)
  21. 330 g (13)
  22. 350 g (2)
  23. 400 g (2)
  24. 800 g (2)
Particle Size
  1. 40-63 µm / 230-400 mesh (23)

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