Drug Discovery
SiliCycle is a recognized industry leader of innovative methods for more efficiency in drug discovery.
Our products are particularly well suited for drug discovery chemists that perform amide couplings, reductive aminations, metal mediated couplings, etc., on a daily basis. Our supported reagents and catalysts greatly simplify the reaction and work-up process, enabling chemists to run more reactions and generate more compounds. Furthermore, we have a whole range of flash cartridges and TLC plates to assist the chemists in the purification of these compounds.
We are your partner of choice for all your synthesis, catalysis, analysis, purification and metal removal requirements.
We commit ourselves to offer you best quality products accompanied by expert technical support at a competitive price!
- Under a CDA, we will screen a customer’s metal contaminated reaction mixture against our SiliaMetS® Metal scavengers to determine the best scavenger and the best conditions.
Custom Phase Synthesis:
- We have the knowledge to graft any function (small molecules, peptides, sugars, and proteins) onto silica gel and we do that for a customer’ specific application for catalysis, support, or chromatography.
CONTACT US for more details
- Our team of dedicated specialist will answer your questions, no matter how technical they are.
Products of Interest:
- New SiliaBond® C18
- SiliaMetS® Metal Scavengers
- SiliaBond® Reagents
- SiliaCat® Heterogeneous Catalysts
- SiliaFlash® Irregular Silica Gels
- SiliaSep™ Flash Cartridges HP
- SiliaSep™ Accessories
- SiliaPrep™ SPE (scx-carbonate-NH2)
- SiliaPrep™ Well Plates
- SiliaPlates™ TLC Plates
- METTLER TOLEDO MiniBlock®
Applications:
- Scavenging Palladium Catalysts
- Scavenging Pd(Dppf)Cl2 Catalyst
- SiliaBond® Metal Scavenger: Compatible With RCM Reaction
- SiliaBond® (Bulk) & SiliaPrep™ (SPE) Scavenging Efficiency Comparison
- SiliaBond® Metal Scavenger: Easily Scalable
- Use Of SiliaBond® TMA Acetate
- TFA Removal Using SiliaPrep™ Carbonate
- Scavenging HOBt With SiliaBond® Carbonate
- TLC Troubleshooting: Switching To SiliaPlate™ TLC
- Amide Coupling Using SiliaBond® Dichlorotriazine & Carbodiimide
- Reductive Amination - Use Of SiliaBond® Cyanoborohydride
- Friedel-Crafts Alkylation
- Use Of SiliaCat® TEMPO
- Use Of SiliaCat® DPP-Pd
- Use Of SiliaCat® S-Pd
Posters:
- SiliaBond Metal Scavengers: An Efficient Tool to Remove Metal Residues From Small to Large Scale APIs Synthesis
- SiliaBond Metal Scavengers: Useful Tool for the Purification of Active Pharmaceutical Ingredients
- Efficient Removal of Ruthenium-Based Catalysts Using SiliaBond Metal Scavengers
- SiliaBond Metal Scavengers: an Efficient Tool to Remove Metal Residues from API's and their Intermediates
- SiliaCat TEMPO: an Effective and Recyclable Oxidizing Catalyst
- SiliaCat S-Pd and SiliaCat DPP-Pd: Highly Reactive and Reusable Heterogeneous Silica-Based Palladium Catalysts
- Functionalized Silica Gels for Amide Coupling Reactions
- SiliaBond Carbonate: a Useful Reagent for Amide Synthesis
- New SiliaBond Coupling Reagents to Expedite Amide and Ester Synthesis
- SiliaSep HP Flash Cartridges: New High Performance Separation Tools
- Efficient Peptide-Protein Purification by Flash Chromatography Based on Silica gel - Effect of Pore Size and Hydrophobicity in Reversed Phase Chromatography
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SiliaSep™ Flash Cartridges - Open Top (OT) Amine
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Open Top (OT) Diol
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Good alternative for difficult separation of low to medium polarity samples. Offer a better retention time compared to normal phase.
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SiliaSep™ Flash Cartridges - Open Top (OT) Propylsulfonic Acid (SCX-2)
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) Tosic Acid (SCX)
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) TMA Chloride nec (SAX)
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
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SiliaSep™ Flash Cartridges - Open Top (OT) Thiol
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
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SiliaSep™ Flash Cartridges - Open Top (OT) Fluorochrom
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Indicated for the purification of fluorous compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Silica
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) C18 nec
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) C18
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Cyano
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Versatile cartridges that can be used either as normal or reversed-phase. Indicated for products with intermediate polarity.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Diol
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Good alternative for difficult separation of low to medium polarity samples. Offer a better retention time compared to normal phase.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Propylsulfonic Acid (SCX-2)
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Silica
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) C18 nec
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Cyano
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Versatile cartridges that can be used either as normal or reversed-phase. Indicated for products with intermediate polarity.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) SCX
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Diol
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Good alternative for difficult separation of low to medium polarity samples. Offer a better retention time compared to normal phase.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) SCX-2
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Fluorochrom
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Indicated for the purification of fluorous compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
- Application Fields
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- Environment (1)
- Food & Beverage (1)
- Forensic (5)
- Metal to Remove
- Family / Formats
- Phases
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- Aluminum Chloride (1)
- Amine (10)
- C18 (19)
- C8 (3)
- Carbodiimide (DCC) (2)
- Carbonate (4)
- CleanDRUG (1)
- CleanENVI (1)
- Cyano (4)
- Cyanoborohydride (1)
- Cysteine (2)
- Diamine (4)
- Dichlorotriazine (DCT) (1)
- Dimercaptotriazine (DMT) (3)
- Diol (4)
- DMAP (1)
- Ethyl Carbodiimide (EDC) (1)
- Fluorochrom (4)
- Imidazole (1)
- Pentafluorophenyl (2)
- Potassium Permanganate (1)
- Propylsulfonic Acid (SCX-2) (9)
- Pyridinium Chlorochromate (PCC) (1)
- Pyridinium Dichromate (PDC) (1)
- SCX (1)
- SCX-2 (1)
- Silica (7)
- TAAcOH (3)
- TAAcONa (3)
- TBD (1)
- Thiol (4)
- Thiourea (3)
- TMA Acetate (5)
- TMA Chloride (SAX) (2)
- Tosic Acid (SCX) (8)
- Triamine (3)
- Tridecafluoro (2)
- Pore Size
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- 60 Å (124)
- Endcapping
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- Endcapped (116)
- Non-endcapped (24)
- Cartridges Volume
- Bed Weight
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- 50 mg (38)
- 100 mg (39)
- 200 mg (27)
- 500 mg (27)
- 1 g (28)
- 2 g (29)
- 4 g (26)
- 5 g (37)
- 8 g (8)
- 9 g (7)
- 10 g (13)
- 12 g (18)
- 15 g (13)
- 20 g (13)
- 25 g (31)
- 40 g (26)
- 45 g (7)
- 50 g (13)
- 70 g (13)
- 80 g (18)
- 90 g (15)
- 100 g (13)
- 120 g (18)
- 135 g (7)
- 200 g (7)
- 220 g (18)
- 330 g (18)
- 350 g (7)
- 400 g (7)
- 800 g (10)
- 1600 g (3)
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