Drug Discovery
SiliCycle is a recognized industry leader of innovative methods for more efficiency in drug discovery.
Our products are particularly well suited for drug discovery chemists that perform amide couplings, reductive aminations, metal mediated couplings, etc., on a daily basis. Our supported reagents and catalysts greatly simplify the reaction and work-up process, enabling chemists to run more reactions and generate more compounds. Furthermore, we have a whole range of flash cartridges and TLC plates to assist the chemists in the purification of these compounds.
We are your partner of choice for all your synthesis, catalysis, analysis, purification and metal removal requirements.
We commit ourselves to offer you best quality products accompanied by expert technical support at a competitive price!
- Under a CDA, we will screen a customer’s metal contaminated reaction mixture against our SiliaMetS® Metal scavengers to determine the best scavenger and the best conditions.
Custom Phase Synthesis:
- We have the knowledge to graft any function (small molecules, peptides, sugars, and proteins) onto silica gel and we do that for a customer’ specific application for catalysis, support, or chromatography.
CONTACT US for more details
- Our team of dedicated specialist will answer your questions, no matter how technical they are.
Products of Interest:
- New SiliaBond® C18
- SiliaMetS® Metal Scavengers
- SiliaBond® Reagents
- SiliaCat® Heterogeneous Catalysts
- SiliaFlash® Irregular Silica Gels
- SiliaSep™ Flash Cartridges HP
- SiliaSep™ Accessories
- SiliaPrep™ SPE (scx-carbonate-NH2)
- SiliaPrep™ Well Plates
- SiliaPlates™ TLC Plates
- METTLER TOLEDO MiniBlock®
Applications:
- Scavenging Palladium Catalysts
- Scavenging Pd(Dppf)Cl2 Catalyst
- SiliaBond® Metal Scavenger: Compatible With RCM Reaction
- SiliaBond® (Bulk) & SiliaPrep™ (SPE) Scavenging Efficiency Comparison
- SiliaBond® Metal Scavenger: Easily Scalable
- Use Of SiliaBond® TMA Acetate
- TFA Removal Using SiliaPrep™ Carbonate
- Scavenging HOBt With SiliaBond® Carbonate
- TLC Troubleshooting: Switching To SiliaPlate™ TLC
- Amide Coupling Using SiliaBond® Dichlorotriazine & Carbodiimide
- Reductive Amination - Use Of SiliaBond® Cyanoborohydride
- Friedel-Crafts Alkylation
- Use Of SiliaCat® TEMPO
- Use Of SiliaCat® DPP-Pd
- Use Of SiliaCat® S-Pd
Posters:
- SiliaBond Metal Scavengers: An Efficient Tool to Remove Metal Residues From Small to Large Scale APIs Synthesis
- SiliaBond Metal Scavengers: Useful Tool for the Purification of Active Pharmaceutical Ingredients
- Efficient Removal of Ruthenium-Based Catalysts Using SiliaBond Metal Scavengers
- SiliaBond Metal Scavengers: an Efficient Tool to Remove Metal Residues from API's and their Intermediates
- SiliaCat TEMPO: an Effective and Recyclable Oxidizing Catalyst
- SiliaCat S-Pd and SiliaCat DPP-Pd: Highly Reactive and Reusable Heterogeneous Silica-Based Palladium Catalysts
- Functionalized Silica Gels for Amide Coupling Reactions
- SiliaBond Carbonate: a Useful Reagent for Amide Synthesis
- New SiliaBond Coupling Reagents to Expedite Amide and Ester Synthesis
- SiliaSep HP Flash Cartridges: New High Performance Separation Tools
- Efficient Peptide-Protein Purification by Flash Chromatography Based on Silica gel - Effect of Pore Size and Hydrophobicity in Reversed Phase Chromatography
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SiliaCat® Heterogeneous Catalysts S-Pd
The significant costs associated with precious metal catalysts and their undesired tendency to remain in organic products has generated interest for an increase in reactivity and ways to recover and reuse these metals. SiliaCat® S-Pd is a unique thiol based palladium (II) heterogeneous catalysts made from a leach-resistant organoceramic matrix.
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