11. SiliaBond® Metal Scavenger: Compatible With RCM Reaction
The use of SiliaBond® Metal Scavengers to remove ruthenium catalyst after ring-closing metathesis (RCM) reaction is the most effective purification method (over conventional ones). As demonstrated herein, the main advantage is no product lost during the purification step.
SiliaMetS® DMT (Si-DMT) is the silica bound equivalent of 2,4,6-trimercaptotriazine (trithiocyanuric acid). It is a versatile metal scavenger for a variety of metals including Cd, Co, Ni, Pd, Pt, Rh, and Ru under a wide range of conditions and the preferred metal scavenger for ruthenium catalysts.
TMT has been reported to efficiently remove palladium and heavy metals by precipitation. Unfortunately, its solubility in organic solvents causes problem. SiliaMetS DMT solves this issue and almost all solvents can now be used.
SiliaSep flash DMT cartridges offer a superior alternative to the other cartridges available on the market.
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.
Cysteine - DMT - Imidazole - Triamine - TAAcOH - TAAcONa - Thiol - Thiourea