Follow SiliCycle on Facebook Follow SiliCycle on Twitter Follow SiliCycle on LinkedIn Watch our videos on Youtube

Won’t the supported reagents leach since they are adsorbed and not bound?

> back to Synthesis and Catalysis FAQ

It depends on how they are used. To be effective, the supported reagents such as Si-KMnO4 should be used in a solvent where the free reagent is not soluble. By doing so, the reagent stays on the silica for which it has more affinity.

If large amount of water is present, the reagent will be completely washed off or destroyed.
For example, when working with Si-KMnO4, an organic solvent such as cyclohexane should be used (see SynLett 2001, 10, 1555-1556).

Unbound PCC and PDC are almost always used as a suspension in DCM, adsorbing it onto silica facilitates its removal. The reagent cannot technically leach since it is not soluble.

 

> back to Synthesis and Catalysis FAQ

1 Item(s)

Set Descending Direction
per page

List  Grid 

  1. Solutions For Organic Synthesis (BROSYN)

    Solutions For Organic Synthesis (BROSYN)

    Brochure, 20 pages. Product line: SiliaBond Reagents, Oxidants, Acids, Bases and Linkers.

1 Item(s)

Set Descending Direction
per page

List  Grid