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How to purify your API from organic contaminants?

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Two Ways SiliaBond Organic Scavengers can help you purify your API from organic contaminants

 

Method 1: Direct scavenging of the undesired compound to isolate the API

  • Silica is bound with a functional group, that will specifically react with a product : either excess reagents (unreacted) or impurities.
  • The API is recovered by simple filtration as demonstrated on the following scheme: purification of API from organic contaminants with organic scavenger

 

Method 2: Catch and release of the API

SiliaBond scavenger is packed in a SPE cartridge:

  • Conditioning step: with six to ten hold-up volumes of solvent
  • Loading step: API is loaded and trapped onto the cartridge bed
  • Washing step: cartridge is washed to filter excess reagents and / or other impurities
  • Elution step: API is eluted, recovered and purified
purification of API from organic contaminants with organic scavenger using catch and release technique

 

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