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SiliaBond TMA Acetate (SAX-2) nec (R66430B)

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SiliaBond TMA Acetate (SAX-2) nec (R66430B)

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Product Number Quantity  
R66430B-10G 10 g

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R66430B-25G 25 g

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R66430B-50G 50 g

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R66430B-100G 100 g

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R66430B-250G 250 g

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R66430B-500G 500 g

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R66430B-1KG 1 kg

Product Description

Specifications


 
  • Details

    Strong anion exchangers (SAX) have been widely used in both chromatography and ion exchange SPE to selectively bind acidic drugs and/or analytes. In particular, weakly acidic compounds can be effectively extracted as those types of sorbents retain a permanent positive charge across the pH range. Most commercially available silica-based SAX sorbents are produced with a high selectivity chloride counter ion which reduced retention of acidic drugs when compared with lower selectivity counter ions such as acetate. Therefore, users traditionally perform the exchange of the chloride ion prior to sample loading. This process can be time consuming and the exchange may be incomplete.

    To this end, SiliCycle has developed SiliaBond® TMA Acetate (Si-TMAAc), a strong anion exchange sorbent with a low selectivity acetate counter ion already in place. Typical loading is 1.0 mmol/g which is higher than other equivalents available on the market.

    This sorbent retains more favorably acidic compounds with pKa < 5, such as carboxylic acid. This property can be used in synthetic chemistry applications to selectively purify acidic compounds or remove acidic impurities from reaction mixtures.

    PRODUCT SPECIFICATIONS

    MSDS-R66430B

    APPLICATION NOTE
    Click here to see the application notes about SiliaBond®

    POSTER
    Click here to see all the documentation about SiliaBond®

  • Additional Information

    Particle Shape Irregular
    Array TMA Acetate (SAX-2)
    Family / Formats SiliaBond® (Functionalized Silicas)
    Particle Size 40 - 63 µm / 230 - 400 mesh
    Pore Size 60 Å
    Endcapping Endcapped
    Storage Condition Keep dry & cool