SiliaBond®- For Organic Synthesis
31 Item(s)
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SiliaBond® Potassium Permanganate nec
Potassium permanganate is a strong oxidant that will oxidize methyl groups and alcohols to carboxylic acids. SiliaBond® Potassium Permanganate (Si-KMnO4) increases recoveries, facilitates work-up, and expands the scope of the chemistry because it can be used in all organic solvents eliminating solubility issues. With SiliaBond Potassium Permanganate, the manganese salt by-products stays adsorbed onto the silica.
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SiliaBond® Pyridinium Chlorochromate nec (PCC)
SiliaBond® Pyridinium Chlorochromate (Si-PCC) is used for the general oxidation of alcohols to carbonyl compounds, selective oxidation of allylic and benzylic alcohols, organometallic oxidation, oxidative transpositions, oxidative cleavages, allylic and benzylic oxidation and oxidative cyclizations.
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SiliaBond® Pyridinium Dichromate nec (PDC)
SiliaBond® Pyridinium Dichromate (Si-PDC) may be used as an alternative to Si-PCC in nucleoside and carbohydrate oxidation, particularly for fragile molecules. SiliaBond PDC can also be used in conjunction with tertbutylhydroperoxide for a variety of oxidative transformations.
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SiliaBond® Diphenylphosphine
SiliaBond® Diphenylphosphine (Si-DPP) can be used as linker for catalyst immobilization such as tetrakis-(triphenylphosphine)palladium(0) for Suzuki coupling.
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SiliaBond® Propylsulfonic Acid (SCX-2)
Supported sulfonic acids such as SiliaBond® Propylsulfonic Acid (SiliaBond SCX-2) are in a class of strong acids widely used in different fields of synthetic organic chemistry. Their applications are well known and are used in a large number of settings going from drug discovery laboratories up to manufacturing processes. Among these applications, we denote their uses as acid catalysts, stationary phases for ion chromatography and basic impurity scavengers. Meanwhile, the most common use is probably as a strong cation exchanger (SCX) for the amine “Catch and Release” purification technique in SPE cartridges.
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SiliaBond® Propylsulfonic Acid nec (SCX-2)
Supported sulfonic acids such as SiliaBond® Propylsulfonic Acid (SiliaBond SCX-2) are in a class of strong acids widely used in different fields of synthetic organic chemistry. Their applications are well known and are used in a large number of settings going from drug discovery laboratories up to manufacturing processes. Among these applications, we denote their uses as acid catalysts, stationary phases for ion chromatography and basic impurity scavengers. Meanwhile, the most common use is probably as a strong cation exchanger (SCX) for the amine “Catch and Release” purification technique in SPE cartridges.
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SiliaBond® Dichlorotriazine (DCT)
Amide bond formation is certainly among the most common chemical transformation in organic synthesis. This explains the diversity of possible reaction pathways and reagents available on the market. SiliCycle is part of this trend and this is why we have developed the bound equivalent of 2,4,6-trichloro-1,3,5-triazine(cyanuric chloride), SiliaBond® Dichlorotriazine (Si-DCT).
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SiliaBond® Tosic Acid nec (SCX)
SiliaBond® Tosic Acid (SiliaBond SCX, Si-TsOH) is a versatile bound strong acid with a pka <<1. It is widely used for the scavenging of amines and other basic functionalities, including weakly basic anilines, borohydrides, and metals such as Ni and Ag. It can also be used as an acid catalyst for organic reactions.6 Si-TsOH can serve as an alternative method to quench reactions instead of aqueous or organic soluble acids.
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SiliaBond® Tosic Acid (SCX)
SiliaBond® Tosic Acid (SiliaBond SCX, Si-TsOH) is a versatile bound strong acid with a pka <<1. It is widely used for the scavenging of amines and other basic functionalities, including weakly basic anilines, borohydrides, and metals such as Ni and Ag. It can also be used as an acid catalyst for organic reactions.6 Si-TsOH can serve as an alternative method to quench reactions instead of aqueous or organic soluble acids.
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SiliaBond® Cyanoborohydride
SiliaBond® Cyanoborohydride (Si-CBH) is the silica bound equivalent of sodium cyanoborohydride. Bound cyanoborohydride is very useful in reductive amination and in the reduction of imines and aldehydes. This problem is minimized with the use of silica bound materials since the toxic cyanide residue remains on the silica.
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SiliaBond® Carbodiimide (DCC)
SiliaBond® Carbodiimide (Si-DCC) is a bound neutral carbodiimide that may be used for the synthesis of amides, esters, and activated esters.
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SiliaBond® Ethyl Carbodiimide (EDC)
SiliaBond® Ethyl-Dimethylaminopropyl Carbodiimide (Si-EDC) reacts in a similar fashion to SiliaBond Carbodiimide (Si-DCC). The advantage of Si-EDC is this new reagent greatly simplifies the work up procedure of the reactions since a simple filtration is all that takes to remove the unwanted side product of the amides formation (urea).
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SiliaBond® DMAP
SiliaBond® DMAP (Si-DMAP) is the supported equivalent of 4-dimethylaminopyridine commonly used as a nucleophilic catalyst in a wide variety of reactions such as acylation, amidation or acetylation.
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SiliaBond® Oxidant Kit
Potassium Permanganate - TEMPO - Pyridinium Chlrorochromate - Pyridinium dichromate -
SiliaBond® Reagent Kit
Carbodiimide - Cyanoborohydride - Dichlorotriazine - DMAP - EDC - HOBt -
SiliaBond® TBD
SiliaBond® TBD (1,5,7-Triazabicyclo[4.4.0]dec-5-ene, Si-TBD) is a silica bound bicyclic guanidine moiety that is sufficiently basic to deprotonate moderately acidic hydrogens. It is most commonly used for the alkylation of phenols (Williamson ether synthesis) and amines, and the esterification of carboxylic acids using alkyl halides. It may also be used to scavenge boronic acids such as phenylboronic acid: 98% removal with 1 equivalent in DCM at room temperature after 1 h.
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SiliaPrep™ SPE Cartridges Carbodiimide (DCC)
SiliaPrep Dichlorotriazine has been designed as a reagent for amide coupling applications.
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SiliaPrep™ SPE Cartridges Dichlorotriazine (DCT)
SiliaPrep Dichlorotriazine has been designed as a reagent for amide coupling applications.
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SiliaBond® Carbonate
SiliaBond® Carbonate (Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.
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SiliaBond® Aluminum Chloride
SiliaBond® Aluminium Chloride (Si-AlClx) is the silica supported version of the most widely used Lewis acid, aluminium chloride. It is an effective catalyst for Friedel-Crafts alkylations and acylations. It also catalyzes the formation of ethers.
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SiliaPrep™ SPE Cartridges Tosic Acid (SCX)
SiliaPrep Tosic Acid (SCX) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
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SiliaPrep™ SPE Cartridges Tosic Acid nec (SCX)
SiliaPrep Tosic Acid is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
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SiliaPrep™ SPE Cartridges Propylsulfonic Acid (SCX-2)
SiliaPrep Propylsulfonic Acid (SCX-2) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
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SiliaPrep™ SPE Cartridges Propylsulfonic Acid nec (SCX-2)
SiliaPrep Propylsulfonic Acid nec is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
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SiliaPrep™ SPE Cartridges Carbonate
SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.
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SiliaPrep™ 96 Well Plates Carbonate
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
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SiliaPrep™ 96 Well Plates Tosic Acid (SCX)
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
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SiliaPrep™ 96 Well Plates Tosic Acid nec (SCX)
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
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SiliaPrep™ 96 Well Plates Propylsulfonic Acid (SCX-2)
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
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SiliaPrep™ 96 Well Plates Propylsulfonic Acid nec (SCX-2)
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
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SiliaPrep™ 96 Well Plates SCX-2/SAX
Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
31 Item(s)
List Grid
- Family / Formats
- Phases
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- Aluminum Chloride (1)
- Carbodiimide (DCC) (3)
- Carbonate (3)
- Cyanoborohydride (2)
- Dichlorotriazine (DCT) (3)
- Diphenylphosphine (1)
- DMAP (2)
- Ethyl Carbodiimide (EDC) (2)
- HOBt (1)
- Potassium Permanganate (2)
- Propylsulfonic Acid (SCX-2) (6)
- Pyridinium Chlorochromate (PCC) (2)
- Pyridinium Dichromate (PDC) (2)
- TBD (1)
- TEMPO (1)
- Tosic Acid (SCX) (6)
- Pore Size
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- 60 Å (29)
- Endcapping
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- Endcapped (26)
- Non-endcapped (9)
- Cartridges Volume
- Bed Weight
- Particle Size
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