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SiliaBond®- Electrophile Scavengers

In order to simplify the removal of electrophile impurities from reaction mixtures, SiliCycle has developed a range of silica bound Electrophile scavengers. See scavengers below;

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  1. SiliaBond® Amine nec

    SiliaBond® Amine nec

    SiliaBond® Amine (Si-NH2) is an effective scavenger of acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles. Si-NH2 has been shown to be effective metal scavenger and catalyst for Knoevenagel reactions. SiliaBond Amine is also used in chromatography as normal phase sorbent.

  2. SiliaBond® Piperazine

    SiliaBond® Piperazine

    SiliaBond® Piperazine (Si-PPZ) is a useful deprotecting and scavenging agent for Fmoc1 and Bsmoc2 amino protecting groups and as a solid-phase Knoevenagel catalyst. According to the results of a study1, Si-PPZ is superior to its polystyrene-based equivalent. SiliaBond Piperazine may also be used to scavenge electrophiles.


  3. SiliaBond® Tosyl Hydrazine

    SiliaBond® Tosyl Hydrazine

    SiliaBond® Tosyl Hydrazine (Si-TsNHNH2) is an effective scavenger of carbonyl compounds. It has been used to selectively remove aldehydes in the presence of ketones since the scavenging of ketones requires an acid catalyst. Once bound, sulfonyl hydrazones can be utilized in other synthetic transformations.

  4. SiliaBond® DMAP

    SiliaBond® DMAP

    SiliaBond® DMAP (Si-DMAP) is the supported equivalent of 4-dimethylaminopyridine commonly used as a nucleophilic catalyst in a wide variety of reactions such as acylation, amidation or acetylation.

  5. SiliaBond Electrophile Introductory Scavenger Kit (K34230B) - Includes the following products: Amine - DMAP - Diamine - Tosyl Hydrazine - Piperazine - Triamine

    SiliaBond® Electrophile Introductory Scavenger Kit (K34230B)

    This kit includes the following products: Amine - DMAP - Diamine - Tosyl Hydrazine - Piperazine - Triamine
  6. SiliaMetS® Triamine

    SiliaMetS® Triamine

    SiliaMetS® Triamine (SiliaMetS WAX-3, Si-TRI) is effective for scavenging metals such as Pb, Co, Ru and Pd. Our screening studies have shown it to be the preferred scavenger for Pb. It can also be used as a scavenger for acid chlorides, isocyanates and other electrophiles.

  7. SiliaMetS® Diamine

    SiliaMetS® Diamine

    SiliaMetS® Diamine (Si-DIA) is a proven scavenger for metals and electrophiles. It scavenges acids, acid chlorides, anhydrides, aldehydes, isocyanates, and chloroformates as well as Pb, Ni, and Cd.

  8. SiliaBond® Amine

    SiliaBond® Amine

    SiliaBond® Amine (Si-NH2) is an effective scavenger of acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles. Si-NH2 has been shown to be effective metal scavenger and catalyst for Knoevenagel reactions. SiliaBond Amine is also used in chromatography as normal phase sorbent.

  9. SiliaPrep™ SPE Cartridges Amine (WAX)

    SiliaPrep™ SPE Cartridges Amine (WAX)

    SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and in normal phase conditions.

  10. SiliaPrep™ SPE Cartridges Amine nec (WAX)

    SiliaPrep™ SPE Cartridges Amine nec (WAX)

    SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.

  11. SiliaPrep™ SPE Cartridges Piperazine (SPE-R60030B)

    SiliaPrep™ SPE Cartridges Piperazine (SPE-R60030B)

    SiliaPrep Piperazine is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. By using this phase, elution can be done at a lower pH (around pH 8-9) comparatively to the SiliaPrep Amine.

  12. SiliaPrep™ SPE Cartridges Diamine

    SiliaPrep™ SPE Cartridges Diamine

    SiliaPrep Diamine can be used in replacement of SAX for strong anions. It can also be employed as metal scavenger and in normal phase conditions.

  13. SiliaPrep™ SPE Cartridges Diamine nec

    SiliaPrep™ SPE Cartridges Diamine nec

    SiliaPrep diamine can be used in replacement of SAX for strong anions to be irreversible retention. Can also be employed as metal scavenger and in normal-phase conditions.

  14. SiliaPrep™ SPE Cartridges Triamine

    SiliaPrep™ SPE Cartridges Triamine

    SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.

  15. SiliaPrep™ SPE Cartridges - Double Layer Activated Carbon/Amine (WAX)

    SiliaPrep™ SPE Cartridges - Double Layer Activated Carbon/Amine (WAX)

    SiliaPrep double layer activated carbon/amine cartridges are packed with pure graphitized carbon black stacked on the amine phase.

  16. SiliaPrep™ SPE Cartridges - Double Layer Activated Carbon/Diamine (PSA)

    SiliaPrep™ SPE Cartridges - Double Layer Activated Carbon/Diamine (PSA)

    SiliaPrep double layer activated carbon/diamine cartridges are packed with pure graphitized carbon black stacked on the diamine phase.

  17. SiliaPrep™ 96 Well Plates Amine

    SiliaPrep™ 96 Well Plates Amine


    Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
  18. SiliaPrep™ 96 Well Plates Amine nec

    SiliaPrep™ 96 Well Plates Amine nec


    Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
  19. SiliaBond Nucleophile Complete Scavenger Kit

    SiliaBond® Electrophile Complete Scavenger Kit (K35230B)

    This kit includes the following products: Amine - DEAM - Diol - DMAP - TMA Acetate - Triamine

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