SiliaBond®- Electrophile Scavengers
In order to simplify the removal of electrophile impurities from reaction mixtures, SiliCycle has developed a range of silica bound Electrophile scavengers. See scavengers below;
SiliaBond® Piperazine (Si-PPZ) is a useful deprotecting and scavenging agent for Fmoc1 and Bsmoc2 amino protecting groups and as a solid-phase Knoevenagel catalyst. According to the results of a study1, Si-PPZ is superior to its polystyrene-based equivalent. SiliaBond Piperazine may also be used to scavenge electrophiles.
Amine - Diamine - Triamine - DMAP - Piperazine - Tosyl Hydrazine
SiliaPrep Piperazine is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. By using this phase, elution can be done at a lower pH (around pH 8-9) comparatively to the SiliaPrep Amine.