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SiliaBond®- Genotoxic Impurities Scavengers

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  1. SiliaBond® Piperazine

    SiliaBond® Piperazine

    SiliaBond® Piperazine (Si-PPZ) is a useful deprotecting and scavenging agent for Fmoc1 and Bsmoc2 amino protecting groups and as a solid-phase Knoevenagel catalyst. According to the results of a study1, Si-PPZ is superior to its polystyrene-based equivalent. SiliaBond Piperazine may also be used to scavenge electrophiles.


  2. SiliaBond® Tosyl Hydrazine

    SiliaBond® Tosyl Hydrazine

    SiliaBond® Tosyl Hydrazine (Si-TsNHNH2) is an effective scavenger of carbonyl compounds. It has been used to selectively remove aldehydes in the presence of ketones since the scavenging of ketones requires an acid catalyst. Once bound, sulfonyl hydrazones can be utilized in other synthetic transformations.

  3. SiliaBond® Piperidine

    SiliaBond® Piperidine

    SiliaBond® Piperidine (Si-PIP) is a general purpose tertiary amine base to scavenge acids, thereby avoiding salt elimination problems. Also used as a base catalyst for Knoevenagel condensation.

  4. SiliaMetS® Triamine

    SiliaMetS® Triamine

    SiliaMetS® Triamine (SiliaMetS WAX-3, Si-TRI) is effective for scavenging metals such as Pb, Co, Ru and Pd. Our screening studies have shown it to be the preferred scavenger for Pb. It can also be used as a scavenger for acid chlorides, isocyanates and other electrophiles.

  5. SiliaMetS® Diamine

    SiliaMetS® Diamine

    SiliaMetS® Diamine (Si-DIA) is a proven scavenger for metals and electrophiles. It scavenges acids, acid chlorides, anhydrides, aldehydes, isocyanates, and chloroformates as well as Pb, Ni, and Cd.

  6. SiliaMetS thiol metal scavenger - Best scavenger: Ag, Hg, Os, Pd & Ru - Good scavenger: Cu, Ir, Pb, Rh & Sn

    SiliaMetS® Thiol metal scavenger

    SiliaMetS Thiol is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions.
  7. SiliaMetS Dimercaptotriazine (DMT) metal scavenger

    SiliaMetS® Dimercaptotriazine (DMT)

    SiliaMetS DMT is the silica - bound equivalent of 2,4,6 - trimercaptotriazine (trithiocyanuric acid, TMT). It is a versatile metal scavenger for a variety of metals and the preferred metal scavenger for ruthenium catalysts and hindered Pd complexes (i.e. Pd(dppf)Cl2).
  8. SiliaPrep™ SPE Cartridges Piperazine (SPE-R60030B)

    SiliaPrep™ SPE Cartridges Piperazine (SPE-R60030B)

    SiliaPrep Piperazine is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. By using this phase, elution can be done at a lower pH (around pH 8-9) comparatively to the SiliaPrep Amine.

  9. SiliaPrep™ SPE Cartridges Diamine

    SiliaPrep™ SPE Cartridges Diamine

    SiliaPrep Diamine can be used in replacement of SAX for strong anions. It can also be employed as metal scavenger and in normal phase conditions.

  10. SiliaPrep™ SPE Cartridges Diamine nec

    SiliaPrep™ SPE Cartridges Diamine nec

    SiliaPrep diamine can be used in replacement of SAX for strong anions to be irreversible retention. Can also be employed as metal scavenger and in normal-phase conditions.

  11. SiliaPrep™ SPE Cartridges Triamine

    SiliaPrep™ SPE Cartridges Triamine

    SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.

  12. SiliaPrep™ SPE Cartridges Thiol

    SiliaPrep™ SPE Cartridges Thiol

    SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.

  13. SiliaPrep™ SPE Cartridges Dimercaptotriazine (DMT)

    SiliaPrep™ SPE Cartridges Dimercaptotriazine (DMT)

    SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.

  14. SiliaPrep™ SPE Cartridges - Double Layer Activated Carbon/Diamine (PSA)

    SiliaPrep™ SPE Cartridges - Double Layer Activated Carbon/Diamine (PSA)

    SiliaPrep double layer activated carbon/diamine cartridges are packed with pure graphitized carbon black stacked on the diamine phase.

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