SiliaBond®- Scavengers
SiliCycle offers a wide range of scavengers to simplify your purifications.
Scavengers are functionalized silica gels designed to react and bind excess reagents, metal complexes and/or by-products.More Information
The process for using scavengers is outlined in the scheme shown below. In the case of batch processing, the scavenger is added to the reaction mixture after completion. The process relies on chemically driven reactions where the excess reagents and reaction by-products react with and bind to the scavenger. The solution, which now only contains the product of interest, is separated from the silica bound impurities by filtration.
For flow through processing, the scavenger is packed into a column and the reaction mixture is passed through the column until complete scavenging is obtained.
SiliCycle Available Scavengers:
8 Item(s)
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SiliaMetS® Diamine
SiliaMetS® Diamine (Si-DIA) is a proven scavenger for metals and electrophiles. It scavenges acids, acid chlorides, anhydrides, aldehydes, isocyanates, and chloroformates as well as Pb, Ni, and Cd.
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SiliaMetS® Thiol
SiliaMetS® Thiol (Si-Thiol) is a robust metal scavenger for a variety of metals including Pd, Pt, Cu, Ag and Pb under a wide range of conditions. It has been used in pharmaceutical processes up to the pilot plant scale. It is our most versatile metal scavenger and is the preferred metal scavenger for Pd(II), Cu, Ag, and Hg.
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SiliaBond® Amine
SiliaBond® Amine (Si-NH2) is an effective scavenger of acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles. Si-NH2 has been shown to be effective metal scavenger and catalyst for Knoevenagel reactions. SiliaBond Amine is also used in chromatography as normal phase sorbent.
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SiliaPrep™ SPE Cartridges Diamine
SiliaPrep diamine can be used in replacement of SAX for strong anions to be irreversible retention. Can also be employed as metal scavenger and in normal-phase conditions.
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SiliaPrep™ SPE Cartridges Diamine nec
SiliaPrep diamine can be used in replacement of SAX for strong anions to be irreversible retention. Can also be employed as metal scavenger and in normal-phase conditions.
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SiliaPrep™ SPE Cartridges Thiol
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.
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SiliaPrep™ SPE Cartridges Amine (WAX)
SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.
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SiliaPrep™ SPE Cartridges Amine nec (WAX)
SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.
8 Item(s)
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- Metal to Remove
- Family / Formats
- Phases
- Pore Size
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- 60 Å (8)
- Endcapping
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- Endcapped (8)
- Non-endcapped (1)
- Cartridges Volume
- Bed Weight
- Particle Size
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