SiliaBond®- Scavengers
SiliCycle offers a wide range of scavengers to simplify your purifications.
Scavengers are functionalized silica gels designed to react and bind excess reagents, metal complexes and/or by-products.More Information
The process for using scavengers is outlined in the scheme shown below. In the case of batch processing, the scavenger is added to the reaction mixture after completion. The process relies on chemically driven reactions where the excess reagents and reaction by-products react with and bind to the scavenger. The solution, which now only contains the product of interest, is separated from the silica bound impurities by filtration.
For flow through processing, the scavenger is packed into a column and the reaction mixture is passed through the column until complete scavenging is obtained.
SiliCycle Available Scavengers:
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SiliaMetS® Thiol
SiliaMetS® Thiol (Si-Thiol) is a robust metal scavenger for a variety of metals including Pd, Pt, Cu, Ag and Pb under a wide range of conditions. It has been used in pharmaceutical processes up to the pilot plant scale. It is our most versatile metal scavenger and is the preferred metal scavenger for Pd(II), Cu, Ag, and Hg.
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SiliaPrep™ SPE Cartridges Thiol
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.
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