
SiliaMetS® Compatible with New Technologies
SiliaMetS In Flow Chemistry
Metal scavenging can also be achieved using SiliaMetS in flow chemistry applications. Simply place SiliaMetSinside solid-phase reactors coming with the flow system (like Syrris Asia® Solid Phase Chemistry Reactors) and let flow the solution to be purified inside these reactors. Multiple reactors can be placed in series and reactors can be heated to obtain optimum scavenging conditions.
SiliaMetS In Microwave
Metal removal using SiliaMetS can also be used under microwave irradiation to provide excellent scavenging efficiency in a few minutes. Simply mix the scavenger and the API dissolved in a suitable solvent inside a microwave tube and set-up the system with the appropriate parameters. Usually, 5 minutes is enough to scavenge all residual metals.
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SiliaBond® Amine
SiliaBond® Amine (Si-NH2) is an effective scavenger of acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles. Si-NH2 has been shown to be effective metal scavenger and catalyst for Knoevenagel reactions. SiliaBond Amine is also used in chromatography as normal phase sorbent.
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SiliaMetS® Dimercaptotriazine (DMT)
SiliaMetS® DMT (Si-DMT) is the silica bound equivalent of 2,4,6-trimercaptotriazine (trithiocyanuric acid). It is a versatile metal scavenger for a variety of metals including Cd, Co, Ni, Pd, Pt, Rh, and Ru under a wide range of conditions and the preferred metal scavenger for ruthenium catalysts.
TMT has been reported to efficiently remove palladium and heavy metals by precipitation. Unfortunately, its solubility in organic solvents causes problem. SiliaMetS DMT solves this issue and almost all solvents can now be used.
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SiliaMetS® Diamine
SiliaMetS® Diamine (Si-DIA) is a proven scavenger for metals and electrophiles. It scavenges acids, acid chlorides, anhydrides, aldehydes, isocyanates, and chloroformates as well as Pb, Ni, and Cd.
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SiliaMetS® Triamine
SiliaMetS® Triamine (SiliaMetS WAX-3, Si-TRI) is effective for scavenging metals such as Pb, Co, Ru and Pd. Our screening studies have shown it to be the preferred scavenger for Pb. It can also be used as a scavenger for acid chlorides, isocyanates and other electrophiles.
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SiliaSep™ Flash Cartridges Amine
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
SiliaSep flash amine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Triamine
SiliaSep flash triamine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Diamine
SiliaSep flash diamine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Dimercaptotriazine (DMT)
SiliaSep flash DMT cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges - Open Top (OT) Amine
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Biotage™ Compatible (BT) Amine
SiliaSep™ BT flash cartridges are compatible with Biotage i-style compression modules.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Büchi™ Compatible (BU) Amine
SiliaSep™ BU flash cartridges are compatible with Büchi Sepacor flash chromatography instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaPrep™ SPE Cartridges Amine (WAX)
SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.
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SiliaPrep™ SPE Cartridges Amine nec (WAX)
SiliaPrep Amine nec is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and norman phase conditions.
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SiliaPrep™ SPE Cartridges Diamine
SiliaPrep diamine can be used in replacement of SAX for strong anions to be irreversible retention. Can also be employed as metal scavenger and in normal-phase conditions.
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SiliaPrep™ SPE Cartridges Diamine nec
SiliaPrep diamine can be used in replacement of SAX for strong anions to be irreversible retention. Can also be employed as metal scavenger and in normal-phase conditions.
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SiliaPrep™ SPE Cartridges Triamine
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.
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SiliaPrep™ SPE Cartridges Dimercaptotriazine (DMT)
SiliaPrep Metal Scavengers will lower the residual metal concentration of various metal complexes to single digit ppm.





