SiliCycle manufactures a variety of HPLC columns for reversed and normal phases applications. The SiliaChrom series contain more than 20 different phases produced in our own laboratories, and we continue to develop additional unique and powerful HPLC columns. In fact, you can be completely assured of the quality, from raw material synthesis through packing, testing and customer applications.
SiliaChrom HPLC columns are made of highly pure spherical particles. One of the most remarkable properties of every SiliaChrom column is that all types of organic compounds (acidic, basic and neutral) will have optimal peak symmetry with excellent efficiency across the whole applicable pH range. Lot-to-lot reproducibility is ensured by a stable bonding and endcapping process. All columns are packed using a consistent slurry packing process to achieve uniform and stable bed for maximum column efficiency, long lifetime and column-to-column reproducibility.
SiliaChrom HPLC Columns
| Main characteristics > | Benefits for the column users |
|---|---|
| Broad pH range (0,8-12,0) | Flexibility for method development |
| Compatible with 100% aqueous mobile phase | Maximum versatility |
| High surface coverage | Tolerance to large volume and mass injected |
| Minimum buffer concentration needed | Better sensitivity for LC-MS and column lifetime |
| Low bleed | High sensitivity for LC-MS |
| Wide variety of chemistries available | Broad selection of polarity |
| Excellent column effiency | Better and faster separation |
| Long column lifetime | Lower cost |
| Thightest specification | Better confidence in HPLC results |
SiliCycle is also an authorized distributor of HPLC columns from other suppliers:
 nacalai tesque inc. - Specialized HPLC Columns Sugar-D, Cholester, HILIC, π-NAP |
 SIELC Technologies - Mixed Mode Stationary Phases HPLC Columns |
The pore size of this silica support is intermediate, 150 Å, which separates larger molecules than its 100 Å equivalent. The lower surface area of this phase allows compounds to have shorter retention times on the column.
The pore size of this silica support is intermediate, 150 Å, which separates larger molecules than its 100 Å equivalent. The lower surface area of this phase allows compounds to have shorter retention times on the column.
SiliaChrom® XDB C18 presents the same bonded phase as the SiliaChrom XDB 1 C18 and XDB1 C18-300. The pore size of the silica support is intermediate, 150 Å, which allows to separate larger molecules than its 100 Å equivalent. The lower surface associated allows compounds to have shorter retention times. SiliaChrom XDB C18 is an excellent equivalent to Hypersil BDS-C18 and Zorbax XDB-C18.
SiliaChrom® XDB C18 presents the same bonded phase as the SiliaChrom XDB 1 C18 and XDB1 C18-300. The pore size of the silica support is intermediate, 150 Å, which allows to separate larger molecules than its 100 Å equivalent. The lower surface associated allows compounds to have shorter retention times. SiliaChrom XDB C18 is an excellent equivalent to Hypersil BDS-C18 and Zorbax XDB-C18.
SiliaChrom® XDB C8 presents the same bonded phase as the SiliaChrom XDB 1 C18 and XDB1 C18-300. The pore size of the silica support is intermediate, 150 Å, which allows to separate larger molecules than its 100 Å equivalent. The lower surface associated allows compounds to have shorter retention times. SiliaChrom XDB C18 is an excellent equivalent to Hypersil BDS-C18 and Zorbax XDB-C18.
SiliaChrom® XDB C8 presents the same bonded phase as the SiliaChrom XDB 1 C18 and XDB1 C18-300. The pore size of the silica support is intermediate, 150 Å, which allows to separate larger molecules than its 100 Å equivalent. The lower surface associated allows compounds to have shorter retention times. SiliaChrom XDB C18 is an excellent equivalent to Hypersil BDS-C18 and Zorbax XDB-C18.
SiliaChrom® XT C18 has a hybrid surface made from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, presents a very high resistance to extreme high pH conditions (up to 12).
SiliaChrom® HILIC (Hydrophilic Interaction Chromatography) HPLC columns are designed to retain highly polar analytes. SiliaChrom HILIC has a selectivity that is complementary to the one of reversed-phase columns. In fact, it has a higher retention for hydrophilic compounds in HILIC mode. HILIC sorbent is more stable and reproducible than normal phase silica or amino columns. This phase is ideal for MedChem laboratories and approved for SFC applications.
SiliaChrom® AQ C8 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology.
SiliaChrom® AQ C18 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology.
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