SiliaChrom®- HILIC HPLC Columns
SiliaChrom HILIC (Hydrophilic Interaction Chromatography) HPLC columns are designed to retain highly polar analytes. SiliaChrom HILIC has a selectivity that is complementary to the one of reversed-phase columns. In fact, it has a higher retention for hydrophilic compounds in HILIC mode. HILIC sorbent is more stable and reproducible than normal phase silica or amino columns. This phase is ideal for MedChem laboratories and approved for SFC application.
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Main Characteristics
- Unique chemistry (urea)
- Accepts normal and reversed phases conditions
- Best replacement for amino HPLC column
- Provides high efficiency and rapid equilibration
- Enhanced sensitivity in mass spectrometry
- Non-endcapped
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GENERAL SiliaChrom HILIC CHARACTERISTICS
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| Columns | Pore Size | Particle Size | Surface Area | Carbon Loading |
| HILIC | 100Å | 3, 5 µm | 410-440 m2/g | 8% |
| Columns | pH Range | Temperature Limit* | Pressure Limit | USP Code |
| HILIC | 2,0-8,0 | 65°C | 5000 psi | N/A |
* At pH range 5 to 7,5
Available column types: Fast analysis, Analytical, Semi-Preparative, Preparative
Application Note
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SiliaChrom® Preparative HPLC Columns HILIC
SiliaChrom® HILIC (Hydrophilic Interaction Chromatography) HPLC columns are designed to retain highly polar analytes. SiliaChrom HILIC has a selectivity that is complementary to the one of reversed-phase columns. In fact, it has a higher retention for hydrophilic compounds in HILIC mode. HILIC sorbent is more stable and reproducible than normal phase silica or amino columns. This phase is ideal for MedChem laboratories and approved for SFC applications.
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SiliaChrom® Semi-Preparative HPLC Columns HILIC-300
The chromatographic HILIC function is grafted on a 300 Å pore size spherical silica to separate or purify larger compounds.
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SiliaChrom® Semi-Preparative HPLC Columns HILIC
SiliaChrom® HILIC (Hydrophilic Interaction Chromatography) HPLC columns are designed to retain highly polar analytes. SiliaChrom HILIC has a selectivity that is complementary to the one of reversed-phase columns. In fact, it has a higher retention for hydrophilic compounds in HILIC mode. HILIC sorbent is more stable and reproducible than normal phase silica or amino columns. This phase is ideal for MedChem laboratories and approved for SFC applications.
-
SiliaChrom® Preparative HPLC Columns HILIC-300
The chromatographic HILIC function is grafted on a 300 Å pore size spherical silica to separate or purify larger compounds.
-
SiliaChrom® Analytical HPLC Columns HILIC
SiliaChrom® HILIC (Hydrophilic Interaction Chromatography) HPLC columns are designed to retain highly polar analytes. SiliaChrom HILIC has a selectivity that is complementary to the one of reversed-phase columns. In fact, it has a higher retention for hydrophilic compounds in HILIC mode. HILIC sorbent is more stable and reproducible than normal phase silica or amino columns. This phase is ideal for MedChem laboratories and approved for SFC applications.
-
SiliaChrom® Analytical HPLC Columns HILIC-300
The chromatographic HILIC function is grafted on a 300 Å pore size spherical silica to separate or purify larger compounds.







