SiliaChrom®- XDB1 HPLC Columns (Normal Phases)
SiliaChrom XDB1 phases present a complete normal phases family HPLC columns (SiO2, Diol, CN, AMINO). These phases present the maximum bonding density. This allows least interaction between the analytes and the surface OH's.
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SiliaChrom XDB1 CN: Maximum hydrophobicity and accepts normal and reversed conditions.
SiliaChrom XDB1 Si: Designed for normal phase conditions, presents high surface area and low metal content.
SiliaChrom® XDB1 DIOL: Excellent for normal phase applications with more hydrophobic activity.
SiliaChrom XDB1 AMINO: Superior general purpose amino phase, recommanded for normal phase analysis and excellent for sugar analysis.

Main Characteristics
- Wide pH range
- High Carbon loading
- Very stable for agressive mobile phases
- Accepts large injection volume (50 µL and more)
- Double endcapped
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GENERAL SiliaChrom XDB1 CHARACTERISTICS
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| Columns |
Pore Size |
Particle Size |
Surface Area |
Carbon Loading |
| CN |
100-300Å |
5 µm |
380-400 m2/g |
5% |
| Si |
100-300Å |
3, 5 µm |
380-400 m2/g |
N/A |
| DIOL |
100-300Å |
5 µm |
380-400 m2/g |
5% |
| AMINO |
100-300Å |
5 µm |
380-400 m2/g |
6% |
| Columns |
pH Range |
Temperature Limit* |
Pressure Limit |
USP Code |
| CN |
2,0-8,5 |
60°C |
5500 psi |
L10 |
| Si |
1,0-8,0 |
45°C |
4000 psi |
L03 |
| DIOL |
2,0-8,0 |
45°C |
4000 psi |
L20 |
| AMINO |
2,0-8,5 |
45°C |
4000 psi |
L08 |
* At pH range 5 to 7,5
Available column types: Fast analysis, Analytical, Semi-Preparative, Preparative
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SiliaChrom® XDB1 CN is a versatile stationary phase which can be used in normal phase or reverse phase conditions. This stationary phase is ideal for basic pharmaceuticals, steroids and other basic compounds.
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SiliaChrom® Amino chromatographic phase functionalization is completely identical to the XDB1 AMINO equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.
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SiliaChrom® XDB1 Si-300 is an ultrapure spherical silica support with a pore size of 300 Å. This spherical silica support is characterized by its very high level of purity (99.999 %).
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SiliaChrom® XDB1 CN-300 chromatography phase functionalization is completely identical to the XDB1 CN equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.
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SiliaChrom® XDB1 NH2 is a very versatile stationary phase which can be used in normal phase, reverse phase or ion exchange conditions as a weak anionic exchanger (WAX).
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SiliaChrom® XDB1 Si is ideal for normal phase applications. This spherical silica support is characterized by its very high level of purity (99.999 %).
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SiliaChrom® XDB1 CN is a versatile stationary phase which can be used in normal phase or reverse phase conditions. This stationary phase is ideal for basic pharmaceuticals, steroids and other basic compounds.
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SiliaChrom® XDB1 NH2 is a very versatile stationary phase which can be used in normal phase, reverse phase or ion exchange conditions as a weak anionic exchanger (WAX).
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SiliaChrom® XDB1 Si is ideal for normal phase applications. This spherical silica support is characterized by its very high level of purity (99.999 %).
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SiliaChrom® XDB1 CN-300 chromatography phase functionalization is completely identical to the XDB1 CN equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.