SiliaChrom®- XDB HPLC Columns
SiliaChrom AQ C18 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology. SiliaChrom AQ C18 is a slightly polar C18 column, and is the most versatile reversed phase column offered by SiliCycle for highly aqueous mobile phases. SiliaChrom AQ C18 is considered as the most universal HPLC column for any type of analytes (acidic, basic and neutral). Furthermore, SiliaChrom AQ C18 is applicable to a wide range of sample types: plasma, urine, drug formulation, food extraction, forensic, clinical and bioanalytical.
Main Characteristics
- Exceptional stability at pH 1,5 to 9,0
- Inertness for acidic and basic analytes
- Compatible from 100% aqueous mobile phase to 100% organic
- Rapid equilibration
- Reduced need for mobile phase modifiers
- Partially endcapped
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GENERAL SiliaChrom AQ CHARACTERISTICS
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|---|---|---|---|---|
| Columns | Pore Size | Particle Size | Surface Area | Carbon Loading |
| C18 | 100Å | 3, 5 µm | 380 m2/g | 18% |
| Columns | pH Range | Temperature Limit* | Pressure Limit | USP Code |
| C18 | 1,5-9,0 | 65°C | 5000 psi | L01 |
* At pH range 5 to 7,5
Available column types: Fast analysis, Analytical, Semi-Preparative, Preparative
Application Notes
SiliaChrom AQ C18 - Cefaclor an Antibiotic Soluble in Water
SiliaChrom AQ C18 - Universal HPLC Column
Evaluation of Resolution and Peak Shape of Acidic, Basic and Neutral Commercial Drugs
SiliaChrom AQ C18, 5 µm, 4,6x150 mm (SiliCycle P/N: HPC-1405-15N)
MPA: 5mM potassium monobasic (adjust to pH 2,5 with H3PO4)/ACN (90/10)
MPB: 5mM potassium monobasic (adjust to pH 2,5 with H3PO4)/ACN (10/90)
Gradient: MPA to MPB, 20 minutes
Temperature: 23°C
Flow rate: 1,0 mL/min
Detector: UV at 230 nm
Injection volume: 20 µL
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COLUMN PERFORMANCE RESULTS
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|---|---|---|---|
| Drugs | Retention Time | Peak Asymmetry Factor | Theoretical Plates |
| (min) | (USP) | (USP) | |
| Maleic acid | 2,46 | 1,84 | 7876 |
| Acetaminophen | 5,53 | 1,04 | 32409 |
| Chlorpheniramine | 7,17 | 1,32 | 63543 |
| Benzoic acid | 10,75 | 1,03 | 93431 |
| Salicylic acid | 11,81 | 1,04 | 102119 |
| Dichlorophen | 17,83 | 1,01 | 231238 |
| Ibuprofen | 18,22 | 1,00 | 209557 |
2 Item(s)
List Grid
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SiliaChrom® Semi-Preparative HPLC Columns AQ C8
SiliaChrom® AQ C8 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology.
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SiliaChrom® Semi-Preparative HPLC Columns AQ C18
SiliaChrom® AQ C18 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology.
2 Item(s)
List Grid
- Application Fields
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- Forensic (2)
- Pharmaceutical (1)
- Chromatographic Mode
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- Reversed Phases (2)
- USP Code
- Family / Formats
- Phases
- Pore Size
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- 100 Å (2)
- Endcapping
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- Endcapped (2)
- Internal Diameter
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- 10 mm (2)
- Length
- Particle Size
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