Twitter LinkedIn

i-pr-siliachrom

SiliaChrom®- HPLC Columns

SiliCycle manufactures a variety of HPLC columns for reversed and normal phases applications. The SiliaChrom series contain more than 20 different phases produced in our own laboratories, and we continue to develop additional unique and powerful HPLC columns. In fact, you can be completely assured of the quality, from raw material synthesis through packing, testing and customer applications.

SiliaChrom HPLC columns are made of highly pure spherical particles. One of the most remarkable properties of every SiliaChrom column is that all types of organic compounds (acidic, basic and neutral) will have optimal peak symmetry with excellent efficiency across the whole applicable pH range. Lot-to-lot reproducibility is ensured by a stable bonding and endcapping process. All columns are packed using a consistent slurry packing process to achieve uniform and stable bed for maximum column efficiency, long lifetime and column-to-column reproducibility.

SiliaChrom HPLC Columns

Main characteristics  > Benefits for the column users
Broad pH range (0,8-12,0) Flexibility for method development
Compatible with 100% aqueous mobile phase Maximum versatility
High surface coverage Tolerance to large volume and mass injected
Minimum buffer concentration needed Better sensitivity for LC-MS and column lifetime
Low bleed High sensitivity for LC-MS
Wide variety of chemistries available Broad selection of polarity
Excellent column effiency Better and faster separation
Long column lifetime Lower cost
Thightest specification Better confidence in HPLC results

 

Standard HPLC Columns

SiliaChrom HPLC columns are available in Narrow Bore, Analytical, Semi-Preparative, and Preparative formats.

SiliaChrom HPLC Standard Column Dimensions
  SiliaChrom HPLC Column Length (mm)
20
30
50
100
150
200
250
Particle Size (µm)
2.5, 3 & 5
2.5, 3 & 5
2.5, 3, 5, 7 & 10
2.5, 3, 5, 7, 10 & 20
2.5, 3, 5, 7, 10 & 20
5 & 10
2.5, 3, 5, 7, 10 & 20
SiliaChrom
HPLC Column
Internal Diameter (mm)
2.0
S
S
S
S
S
C
C
2.1
S
S
S
S
S
C
C
3.0
C
S
S
S
S
C
C
4.6
C
S
S
S
S
S
S
10
C
C
C
S
S
S
S
20
C
C
C
C
S
S
S
30
C
C
C
S
S
S
S
50
C
C
C
S
S
S
S
100
C
C
C
C
C
C
C
  S = Standard C = Custom

 

Distribution

SiliCycle is also an authorized distributor of HPLC columns from other suppliers:

Nacalai Tesque inc.
nacalai tesque inc. - Specialized HPLC Columns Sugar-D, Cholester, HILIC, π-NAP
SIELC Technologies
SIELC Technologies - Mixed Mode Stationary Phases HPLC Columns

45 Item(s)

Set Descending Direction
per page

List  Grid 

  1. SiliaChrom® Narrow Bore HPLC Columns SB C18

    SiliaChrom® Narrow Bore HPLC Columns SB C18

    SiliaChrom® SB C18 has the particularity that the silane carries two different functions:

    • The C18 Hydrophobic function

    • Transversal hindered isopropyl groups which protect the surface from an acidic attack.

    This chemistry guarantees the stability of this reverse phase in very low pH (up to 0.8)

  2. SiliaChrom® Narrow Bore HPLC Columns SB C8

    SiliaChrom® Narrow Bore HPLC Columns SB C8

    SiliaChrom® SB C18 has the particularity that the silane carries two different functions:

    • The C18 Hydrophobic function

    • Transversal hindered isopropyl groups which protect the surface from an acidic attack.

    This chemistry guarantees the stability of this reverse phase in very low pH (up to 0.8)

  3. SiliaChrom® Narrow Bore HPLC Columns XDB Si

    SiliaChrom® Narrow Bore HPLC Columns XDB Si

    The pore size of this silica support is intermediate, 150 Å, which separates larger molecules than its 100 Å equivalent. The lower surface area of this phase allows compounds to have shorter retention times on the column.

  4. SiliaChrom® Narrow Bore HPLC Columns XDB C18

    SiliaChrom® Narrow Bore HPLC Columns XDB C18

    SiliaChrom® XDB C18 presents the same bonded phase as the SiliaChrom XDB 1 C18 and XDB1 C18-300. The pore size of the silica support is intermediate, 150 Å, which allows to separate larger molecules than its 100 Å equivalent. The lower surface associated allows compounds to have shorter retention times. SiliaChrom XDB C18 is an excellent equivalent to Hypersil BDS-C18 and Zorbax XDB-C18.

  5. SiliaChrom® Narrow Bore HPLC Columns XDB C8

    SiliaChrom® Narrow Bore HPLC Columns XDB C8

    SiliaChrom® XDB C8 presents the same bonded phase as the SiliaChrom XDB 1 C18 and XDB1 C18-300. The pore size of the silica support is intermediate, 150 Å, which allows to separate larger molecules than its 100 Å equivalent. The lower surface associated allows compounds to have shorter retention times. SiliaChrom XDB C18 is an excellent equivalent to Hypersil BDS-C18 and Zorbax XDB-C18.

     

  6. SiliaChrom® Narrow Bore HPLC Columns XDB1 C18

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C18

    SiliaChrom® XDB1 C18 column has the highest loading density available as well as the highest hydrophobicity. This allows it to have the least interactions between the analytes and potential residual silanol groups.

  7. SiliaChrom® Narrow Bore HPLC Columns XDB1 C8

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C8

    SiliaChrom® XDB 1 C8 columns offer faster separations for strongly hydrophobic analytes compared to C18 columns. As the C18 XDB1 phase, the C8 XDB1 is highly base deactivated.

  8. SiliaChrom® Narrow Bore HPLC Columns XDB1 CN

    SiliaChrom® Narrow Bore HPLC Columns XDB1 CN

    SiliaChrom® XDB1 CN is a versatile stationary phase which can be used in normal phase or reverse phase conditions. This stationary phase is ideal for basic pharmaceuticals, steroids and other basic compounds.

  9. SiliaChrom® Narrow Bore HPLC Columns XDB1 Si

    SiliaChrom® Narrow Bore HPLC Columns XDB1 Si

    SiliaChrom® XDB1 Si is ideal for normal phase applications. This spherical silica support is characterized by its very high level of purity (99.999 %).

  10. SiliaChrom® Narrow Bore HPLC Columns XDB1 PHENYL

    SiliaChrom® Narrow Bore HPLC Columns XDB1 PHENYL

    SiliaChrom® XDB1 Phenyl can conjugate hydrophobic interactions and electronic π-π interactions with unsaturated compounds. This stationary phase is excellent for polynuclear aromatic hydrocarbons, purines and polar aromatics.

  11. SiliaChrom® Narrow Bore HPLC Columns XDB1 DIOL

    SiliaChrom® Narrow Bore HPLC Columns XDB1 DIOL

    Useful for your normal phase separation, you will enjoy the efficiency of our diol stationary phase.

  12. SiliaChrom® Narrow Bore HPLC Columns XDB1 AMINO

    SiliaChrom® Narrow Bore HPLC Columns XDB1 AMINO

    SiliaChrom® XDB1 NH2 is a very versatile stationary phase which can be used in normal phase, reverse phase or ion exchange conditions as a weak anionic exchanger (WAX).

  13. SiliaChrom® Narrow Bore HPLC Columns XDB1 C4

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C4

    SiliaChrom® XDB1 C4 presents a less hydrophobic character than C18 and C8 SiliaChrom XDB1 columns. This stationary phase is ideal for peptides and small proteins.

  14. SiliaChrom® Narrow Bore HPLC Columns XDB1 C1

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C1

    SiliaChrom®XDB1 C1 is the least hydrophobic reverse phase available. This phase is useful for very high hydrophobic molecules.

  15. SiliaChrom® Narrow Bore HPLC Columns XDB2 C18

    SiliaChrom® Narrow Bore HPLC Columns XDB2 C18

    SiliaChrom® XDB2 C18 is grafted on ultrapure spherical silica whose surface was activated to create a high concentration of OH before grafting the C18 function. The residual carbon load is lower than the SiliaChrom XDB1 equivalent.

  16. SiliaChrom® Narrow Bore HPLC Columns dt C18

    SiliaChrom® Narrow Bore HPLC Columns dt C18

    SiliaChrom® dt C18 has the same unique technology phase as SiliaChrom AQ C18, but the purity of the spherical silica gel is 99,999%, the highest value for HPLC SiliaChrom Series. 

  17. SiliaChrom® Narrow Bore HPLC Columns dt Si

    SiliaChrom® Narrow Bore HPLC Columns dt Si

    SiliaChrom® dt Si has the same unique technology phase as SiliaChrom AQ Si, but the purity of the spherical silica gel is 99,999%, the highest value for HPLC SiliaChrom Series. This phase has no metal content, in order to avoid secondary interaction with basic or ion species.  

  18. SiliaChrom® Narrow Bore HPLC Columns AQ C18

    SiliaChrom® Narrow Bore HPLC Columns AQ C18

    SiliaChrom® AQ C18 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology. 

  19. SiliaChrom® Narrow Bore HPLC Columns AQ C8

    SiliaChrom® Narrow Bore HPLC Columns AQ C8

    SiliaChrom® AQ C8 columns use a new generation adsorbent based on high purity spherical silica and unique bonding technology.

  20. SiliaChrom® Narrow Bore HPLC Columns HILIC

    SiliaChrom® Narrow Bore HPLC Columns HILIC

    SiliaChrom® HILIC (Hydrophilic Interaction Chromatography) HPLC columns are designed to retain highly polar analytes. SiliaChrom HILIC has a selectivity that is complementary to the one of reversed-phase columns. In fact, it has a higher retention for hydrophilic compounds in HILIC mode. HILIC sorbent is more stable and reproducible than normal phase silica or amino columns. This phase is ideal for MedChem laboratories and approved for SFC applications.

  21. SiliaChrom® Narrow Bore HPLC Columns XT C18

    SiliaChrom® Narrow Bore HPLC Columns XT C18

    SiliaChrom® XT C18 has a hybrid surface made from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, presents a very high resistance to extreme high pH conditions (up to 12).

  22. SiliaChrom® Narrow Bore HPLC Columns XT C18 Fidelity

    SiliaChrom® Narrow Bore HPLC Columns XT C18 Fidelity

    SiliaChrom® XT Fidelity C18 has a hybrid surface composed from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, has an incomparable resistance to extreme high pH conditions (up to 12). The only difference between SiliaChrom XT C18 and SiliaChrom XT Fidelity C18 is the way they are packed, giving Fidelity columns more robustness at high pH and temperature.

  23. SiliaChrom® Narrow Bore HPLC Columns SCX

    SiliaChrom® Narrow Bore HPLC Columns SCX

    Grafted on the purest spherical silica support, this sulfonic acid will allow you to separate basic, water soluble compounds and bio-molecules.

  24. SiliaChrom® Narrow Bore HPLC Columns SAX

    SiliaChrom® Narrow Bore HPLC Columns SAX

    Grafted on the purest spherical silica support, this quaternary amine function will allow you to separate acidic, water soluble compounds and bio-molecules.

  25. SiliaChrom® Narrow Bore HPLC Columns C18/C8

    SiliaChrom® Narrow Bore HPLC Columns C18/C8

    Balance the hydrophobicity of the surface with a C18 function and a shorted hydrocarbon function C8 which play the role of a spacer.

  26. SiliaChrom® Narrow Bore HPLC Columns C18/Amide

    SiliaChrom® Narrow Bore HPLC Columns C18/Amide

    Conjugate the hydrophilic power of the amide functions with the hydrophobic power of the C18 functions for your HPLC applications with our mixed mode C18/amide SiliaChrom® columns.

  27. SiliaChrom® Narrow Bore HPLC Columns C18/Phenyl

    SiliaChrom® Narrow Bore HPLC Columns C18/Phenyl

    Conjugate hydrophobic and aromatic interactions with the mixed mode C18 and phenyl chromatographic stationary phases.

  28. SiliaChrom® Narrow Bore HPLC Columns C18/CN

    SiliaChrom® Narrow Bore HPLC Columns C18/CN

    Conjugate the separation power of the C18 and the CN functions in a same stationary phase with our mixed C18/CN SiliaChrom® columns.

  29. SiliaChrom® Narrow Bore HPLC Columns C18/SCX

    SiliaChrom® Narrow Bore HPLC Columns C18/SCX

    Separate ionic and hydrophobic compounds at the same time. No more need for pairing agent or using columns in series. Gain in efficiency and time by using mixed mode SiliaChrom® HPLC columns.

  30. SiliaChrom® Narrow Bore HPLC Columns C18/SAX

    SiliaChrom® Narrow Bore HPLC Columns C18/SAX

    Separate ionic and hydrophobic compounds at the same time. No more need for pairing agents or for the use of columns in series. Gain in efficiency and time by using mixed mode SiliaChrom® HPLC columns.

  31. SiliaChrom® Narrow Bore HPLC Columns C18/Nitrophenyl

    SiliaChrom® Narrow Bore HPLC Columns C18/Nitrophenyl

    Conjugate the separation power of the C18 and the Nitrophenyl functions in a same stationary phase with our mixed C18/Nitrophenyl SiliaChrom® columns.

  32. SiliaChrom® Narrow Bore HPLC Columns SB C18-300

    SiliaChrom® Narrow Bore HPLC Columns SB C18-300

    SiliaChrom® C18 reverse phase functionalization is completely identical to the SB C18 equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  33. SiliaChrom® Narrow Bore HPLC Columns SB C8-300

    SiliaChrom® Narrow Bore HPLC Columns SB C8-300

    SiliaChrom® C8 reverse phase functionalization is completely identical to the SB C8 equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  34. SiliaChrom® Narrow Bore HPLC Columns XDB1 C18-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C18-300

    SiliaChrom® XDB1 C18-300 reverse phase functionalization is completely identical to the XDB1 C18 equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  35. SiliaChrom® Narrow Bore HPLC Columns XDB1 C8-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C8-300

    SiliaChrom® XDB1 C8-300 reverse phase functionalization is completely identical to the XDB1 C8 equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  36. SiliaChrom® Narrow Bore HPLC Columns XDB1 CN-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 CN-300

    SiliaChrom® XDB1 CN-300 chromatography phase functionalization is completely identical to the XDB1 CN equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  37. SiliaChrom® Narrow Bore HPLC Columns XDB1 Si-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 Si-300

    SiliaChrom® XDB1 Si-300 is an ultrapure spherical silica support with a pore size of 300 Å. This spherical silica support is characterized by its very high level of purity (99.999 %).

  38. SiliaChrom® Narrow Bore HPLC Columns XDB1 PHENYL-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 PHENYL-300

    SiliaChrom® XDB1 Phenyl-300 chromatography phase functionalization is completely identical to the XDB1 Phenyl equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  39. SiliaChrom® Narrow Bore HPLC Columns XDB1 DIOL-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 DIOL-300

    SiliaChrom® XDB1 DIOL-300 chromatography phase functionalization is completely identical to the XDB1 DIOL equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  40. SiliaChrom® Narrow Bore HPLC Columns XDB1 AMINO-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 AMINO-300

    SiliaChrom® Amino chromatographic phase functionalization is completely identical to the XDB1 AMINO equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  41. SiliaChrom® Narrow Bore HPLC Columns XDB1 C4-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C4-300

    SiliaChrom® XDB1 C4-300 reverse phase functionalization is completely identical to the XDB1 C4 equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  42. SiliaChrom® Narrow Bore HPLC Columns XDB1 C1-300

    SiliaChrom® Narrow Bore HPLC Columns XDB1 C1-300

    SiliaChrom® XDB1 C1-300 reverse phase functionalization is completely identical to the XDB1 C1 equivalent. This reverse phase is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  43. SiliaChrom® Narrow Bore HPLC Columns HILIC-300

    SiliaChrom® Narrow Bore HPLC Columns HILIC-300

    The chromatographic HILIC function is grafted on a 300 Å pore size spherical silica to separate or purify larger compounds.

  44. SiliaChrom® Narrow Bore HPLC Columns SCX-300

    SiliaChrom® Narrow Bore HPLC Columns SCX-300

    The strong cationic exchange function is grafted on a 300 Å pore size spherical silica to separate or purify larger molecules.

  45. SiliaChrom® Narrow Bore HPLC Columns SAX-300

    SiliaChrom® Narrow Bore HPLC Columns SAX-300

    The strong anionic exchanger function is grafted on a 300 Å pore size spherical silica to separate or purify larger compounds.

45 Item(s)

Set Descending Direction
per page

List  Grid