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SiliaChrom®- HPLC Columns

SiliCycle manufactures a variety of HPLC columns for reversed and normal phases applications. The SiliaChrom series contain more than 20 different phases produced in our own laboratories, and we continue to develop additional unique and powerful HPLC columns. In fact, you can be completely assured of the quality, from raw material synthesis through packing, testing and customer applications.

SiliaChrom HPLC columns are made of highly pure spherical particles. One of the most remarkable properties of every SiliaChrom column is that all types of organic compounds (acidic, basic and neutral) will have optimal peak symmetry with excellent efficiency across the whole applicable pH range. Lot-to-lot reproducibility is ensured by a stable bonding and endcapping process. All columns are packed using a consistent slurry packing process to achieve uniform and stable bed for maximum column efficiency, long lifetime and column-to-column reproducibility.

SiliaChrom HPLC Columns

Main characteristics  > Benefits for the column users
Broad pH range (0,8-12,0) Flexibility for method development
Compatible with 100% aqueous mobile phase Maximum versatility
High surface coverage Tolerance to large volume and mass injected
Minimum buffer concentration needed Better sensitivity for LC-MS and column lifetime
Low bleed High sensitivity for LC-MS
Wide variety of chemistries available Broad selection of polarity
Excellent column effiency Better and faster separation
Long column lifetime Lower cost
Thightest specification Better confidence in HPLC results

 

Standard HPLC Columns

SiliaChrom HPLC columns are available in Narrow Bore, Analytical, Semi-Preparative, and Preparative formats.

SiliaChrom HPLC Standard Column Dimensions
  SiliaChrom HPLC Column Length (mm)
20
30
50
100
150
200
250
Particle Size (µm)
2.5, 3 & 5
2.5, 3 & 5
2.5, 3, 5, 7 & 10
2.5, 3, 5, 7, 10 & 20
2.5, 3, 5, 7, 10 & 20
5 & 10
2.5, 3, 5, 7, 10 & 20
SiliaChrom
HPLC Column
Internal Diameter (mm)
2.0
S
S
S
S
S
C
C
2.1
S
S
S
S
S
C
C
3.0
C
S
S
S
S
C
C
4.6
C
S
S
S
S
S
S
10
C
C
C
S
S
S
S
20
C
C
C
C
S
S
S
30
C
C
C
S
S
S
S
50
C
C
C
S
S
S
S
100
C
C
C
C
C
C
C
  S = Standard C = Custom

 

Distribution

SiliCycle is also an authorized distributor of HPLC columns from other suppliers:

Nacalai Tesque inc.
nacalai tesque inc. - Specialized HPLC Columns Sugar-D, Cholester, HILIC, π-NAP
SIELC Technologies
SIELC Technologies - Mixed Mode Stationary Phases HPLC Columns

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  1. SiliaChrom® Preparative HPLC Columns XT C18

    SiliaChrom® Preparative HPLC Columns XT C18

    SiliaChrom® XT C18 has a hybrid surface made from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, presents a very high resistance to extreme high pH conditions (up to 12).

  2. SiliaChrom® Semi-Preparative HPLC Columns XT C18

    SiliaChrom® Semi-Preparative HPLC Columns XT C18

    SiliaChrom® XT C18 has a hybrid surface made from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, presents a very high resistance to extreme high pH conditions (up to 12).

  3. SiliaChrom® Semi-Preparative Guard Cartridge XT C18

    SiliaChrom® Semi-Preparative Guard Cartridge XT C18

    The SiliaChrom Guard Cartridges increase the shelf life of the SiliaChrom HPLC Columns by retaining impurities before the analytical columns.

  4. SiliaChrom® Preparative Guard Cartridge XT C18

    SiliaChrom® Preparative Guard Cartridge XT C18

    The SiliaChrom Guard Cartridges increase the shelf life of the SiliaChrom HPLC Columns by retaining impurities before the analytical columns.

  5. SiliaChrom® Narrow Bore HPLC Columns XT C18

    SiliaChrom® Narrow Bore HPLC Columns XT C18

    SiliaChrom® XT C18 has a hybrid surface made from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, presents a very high resistance to extreme high pH conditions (up to 12).

  6. SiliaChrom® Analytical Guard Cartridge XT C18

    SiliaChrom® Analytical Guard Cartridge XT C18

    The SiliaChrom Guard Cartridges increase the shelf life of the SiliaChrom HPLC Columns by retaining impurities before the analytical columns.

  7. SiliaChrom® Analytical HPLC Columns XT C18

    SiliaChrom® Analytical HPLC Columns XT C18

    SiliaChrom® XT C18 has a hybrid surface made from a condensation of inorganic SiO2 species and an organosilane (CH3-SiO1.5). This hybrid, a more hydrophobic matrix, presents a very high resistance to extreme high pH conditions (up to 12).

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