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SiliaSep Portfolio Overview

SiliaSep Ordering Information

For more informations, click on product number links.

SiliaSep Cartridges Ordering Information
SiliaSep Type SiliaSep 4 g SiliaSep 12 g SiliaSep 25 g SiliaSep 40 g SiliaSep 80 g
Quantity per box 20 / box 20 / box 15 / box 15 / box 12 / box
SiliaSep Silica FLH-R10030B-ISO04 FLH-R10030B-ISO12 FLH-R10030B-ISO25 FLH-R10030B-ISO40 FLH-R10030B-ISO80
SiliaSep Silica HP FLH-R10017B-ISO04 FLH-R10017B-ISO12 FLH-R10017B-ISO25 FLH-R10017B-ISO40 FLH-R10017B-ISO80
Other SiliaSep Phases
Quantity per box 2 / box 1 / box 1 / box 1 / box 1 / box
SiliaSep Amine FLH-R52030B-ISO04 FLH-R52030B-ISO12 FLH-R52030B-ISO25 FLH-R52030B-ISO40 FLH-R52030B-ISO80
SiliaSep Diol FLH-R35030B-ISO04 FLH-R35030B-ISO12 FLH-R35030B-ISO25 FLH-R35030B-ISO40 FLH-R35030B-ISO80
SiliaSep Cyano FLH-R38030B-ISO04 FLH-R38030B-ISO12 FLH-R38030B-ISO25 FLH-R38030B-ISO40 FLH-R38030B-ISO80
SiliaSep C18 (17%) FLH-R33230B-ISO04 FLH-R33230B-ISO12 FLH-R33230B-ISO25 FLH-R33230B-ISO40 FLH-R33230B-ISO80
SiliaSep SCX-2 FLH-R51230B-ISO04 FLH-R51230B-ISO12 FLH-R51230B-ISO25 FLH-R51230B-ISO40 FLH-R51230B-ISO80
SiliaSep SAX nec FLH-R66530B-ISO04 FLH-R66530B-ISO12 FLH-R66530B-ISO25 FLH-R66530B-ISO25 FLH-R66530B-ISO80
SiliaSep SAX-2 nec FLH-R66430B-ISO04 FLH-R66430B-ISO12 FLH-R66430B-ISO25 FLH-R66430B-ISO25 FLH-R66430B-ISO80
SiliaSep Cartridges Ordering Information
SiliaSep Type SiliaSep 120 g SiliaSep 220 g SiliaSep 330 g SiliaSep XL 800 g SiliaSep XL 1600 g
Quantity per box 10 / box 4 / box 4 / box 2 / box 2 / box
SiliaSep Silica FLH-R10030B-IS120 FLH-R10030B-IS220 FLH-R10030B-IS330 FLH-R10030B-IS750 FLH-R10030B-I1500
SiliaSep Silica HP FLH-R10017B-IS120 FLH-R10017B-IS220 FLH-R10017B-IS330 - -
Other SiliaSep Phases
Quantity per box 2 / box 1 / box 1 / box 1 / box 1 / box
SiliaSep Amine FLH-R52030B-IS120 FLH-R52030B-IS220 FLH-R52030B-IS330 FLH-R52030B-IS750 FLH-R52030B-I1500
SiliaSep Diol FLH-R35030B-IS120 FLH-R35030B-IS220 FLH-R35030B-IS330 FLH-R35030B-IS750 FLH-R35030B-I1500
SiliaSep Cyano FLH-R38030B-IS120 FLH-R38030B-IS220 FLH-R38030B-IS330 FLH-R38030B-IS750 FLH-R38030B-I1500
SiliaSep C18 (17%) FLH-R33230B-IS120 FLH-R33230B-IS220 FLH-R33230B-IS330 FLH-R33230B-IS750 FLH-R33230B-I1500
SiliaSep SCX-2 FLH-R51230B-IS120 FLH-R51230B-IS220 FLH-R51230B-IS330 FLH-R51230B-IS750 FLH-R51230B-I1500
SiliaSep SAX nec FLH-R66530B-IS120 FLH-R66530B-IS220 FLH-R66530B-IS330 FLH-R66530B-IS750 FLH-R66530B-I1500
SiliaSep SAX-2 nec FLH-R66430B-IS120 FLH-R66430B-IS220 FLH-R66430B-IS330 FLH-R66430B-IS750 FLH-R66430B-I1500

SiliaSep Sorbents for Non-Ionic Compounds

SiliaSep Sorbents for Non-Ionic Compounds Characteristics
Sorbent Structure Characteristics Typical Applications Storage Conditions (Never dry out)
Silica
R10030B
Structure of Silica Part. size: 40 - 63 μm Most popular sorbent for day-to-day use for the purification of non-ionic polar organic compounds Single use recommended.
Silica HP
R10017B
Part. size: 15 - 40 μm High performance sorbent for difficult separations (isomers).
Higher loading capacity. Faster flow rate.
Less solvent used.
Single use recommended.
Amine R52030B Structure of Amine Part. size: 40 - 63 μm Endcapping: Yes %N: ≥ 1.68% Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed phase.
Note: imine formation can be seen with the purification of aldehydes and ketones.
Flush the cartridge 3x with:
- 80% acetonitrile in water
Diol
R35030B
Structure of Diol Part. size: 40 - 63 μm
Endcapping: Yes
%C: ≥ 6.98%
Good alternative for difficult separation of low to medium polarity samples. Offers a better retention time compared to normal phase.
Note: nucleophilic addition reactions can be seen with the purification of ketones and amines (1° and 2°).
Flush the cartridge 3x with:
- 80% acetonitrile in water
Cyano
R38030B
Structure of Cyano Part. size: 40 - 63 μm
Endcapping: Yes
%N: ≥ 1.93%
Versatile sorbent that can be used either as normal or reversed phase. Indicated for products with intermediate to extreme polarity. The slightly hydrophobic nature of the cyano group offers alternative selectivities. Flush the cartridge 3x with:
- 80% methanol in water or
- 80% acetonitrile in water
C18
R33230B
Structure of C18 Part. size: 40 - 63 μm
Endcapping: Yes
%C: 17%
Indicated for the purification of medium to high polarity compounds, SiliaSep C18 are packed with the new generation of SiliaBond C18 monomeric reversed-phase.
They provide reproducible purification without the complexity and cost of preparative HPLC.
Flush the cartridge 3x with:
- 80% methanol in water or
- 80% acetonitrile in water

SiliaSep Sorbents for Ionic Compounds

SiliaSep Sorbents for Ionic Compounds Characteristics
Sorbent Structure Characteristics Typical Applications (single use recommanded)
SCX-2 nec
(propylsulfonic acid)
R51230B
Structure of  Propylsulfonic Acid Part. size: 40 - 63 μm
Endcapping: No
%S: ≥ 2.35%
meq ≥ 0.63 mmol/g
Packed with the strong cation exchange silica SCX-2, they can be used to fully retain basic compounds for clean-up or to isolate them by a catch and release process.
SAX nec
(TMA Chloride)
R66530B
Structure of TMA Chloride Part. size: 40 - 63 μm
Endcapping: No
%N: ≥ 1.42%
meq ≥ 0.8 mmol/g
Packed with the strong anionic exchange silica SAX, they can be used to fully retain acidic compounds for cleanup or to isolate them by a catch and release process.
SAX-2 nec
R66430B
Structure of SAX-2 nec Part. size: 40 - 63 μm
Endcapping: No
%N: ≥ 1.00%
meq ≥ 0.5 mmol/g
Strong anion exchange sorbent with a low selectivity acetate counter ion retains more favorably acidic compounds with pKa’s < 5, such as carboxylic acid.

SiliaSep Sorbent Selection Chart

Other types of cartridges available