SiliaSep™- Flash Cartridges
SiliCycle is the partner of choice for your
flash cartridge needs.
- The use of pre-packed flash cartridges improves purification efficiency by offering superior reproducibility and productivity compared to conventional manual flash chromatography.
- Pre-packed cartridges offer to chromatographers:
- More tightly packed silica bed
- Homogeneous packing
- Better separation

SiliaSep Flash Cartridges
Today, various manufacturers offer pre-packed flash cartridges, but performance and quality varies. SiliCycle supplies pre-packed columns offered under the brand name of SiliaSep Flash Cartridges.
SiliaSep offers superior performances over competitive cartridges. They are available in two silica gel grades (40-63 & 15-40 microns) and with various functionalities (reversed & normal phases, ion exchangers and metal scavengers) to meet any purification demand.
SiliaSep Flash Cartridge Design
Types of cartridges
To better suits your needs, the SiliaSep flash cartridges family includes six types of cartridges that are compatible with different type of instruments:
- SiliaSep (Isco™, Biotage™, Analogix™& Reveleris™ Compatible)
- SiliaSep HP (Isco™, Biotage™, Analogix™ & Reveleris™ Compatible - High Performance)
- SiliaSep XL (Isco CombiFlash Companion XL Compatible)
- SiliaSep BT (Biotage™ i Compatible)
- SiliaSep OT (FlashMaster™ Compatible)
Our flash chromatography products offer high levels of performance and reproducibility. The flash media consistently has a tight particle size distribution with low fines and extremely low metal ion content, for more predictable and easier separations.
Using SiliCycle SiliaSep cartridges, you can purify your sample base on different mechanisms depending on the properties or your compound. Because we can provide cartridges packed with our SiliaBond® functionalized silica gel, you can choose exactly the cartridge that will fit your need. The chart below is designed to serve as a guide in sorbent selection by considering the characteristics of you sample.
SiliaSep Ordering Information
For more informations, click on product number links.
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SiliaSep™ Flash Cartridges - Open Top (OT) Silica
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
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SiliaSep™ Flash Cartridges - Open Top (OT) C18 nec
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
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SiliaSep™ Flash Cartridges - Open Top (OT) C18
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
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SiliaSep™ Flash Cartridges - Open Top (OT) Cyano
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Versatile cartridges that can be used either as normal or reversed-phase. Indicated for products with intermediate polarity.
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SiliaSep™ Flash Cartridges - Open Top (OT) Amine
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
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SiliaSep™ Flash Cartridges - Open Top (OT) Diol
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Good alternative for difficult separation of low to medium polarity samples. Offer a better retention time compared to normal phase.
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SiliaSep™ Flash Cartridges - Open Top (OT) Propylsulfonic Acid (SCX-2)
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) Tosic Acid (SCX)
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) TMA Chloride nec (SAX)
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) TMA Acetate nec
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by “Catch and Release” process.
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SiliaSep™ Flash Cartridges - Open Top (OT) Carbonate
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
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SiliaSep™ Flash Cartridges - Open Top (OT) Thiol
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
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SiliaSep™ Flash Cartridges - Open Top (OT) Fluorochrom
SiliaSep™ OT flash cartridges are compatible with FlashMaster instrument.
Indicated for the purification of fluorous compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.





