SiliaSep™- Flash Cartridges
SiliCycle is the partner of choice for your
flash cartridge needs.
- The use of pre-packed flash cartridges improves purification efficiency by offering superior reproducibility and productivity compared to conventional manual flash chromatography.
- Pre-packed cartridges offer to chromatographers:
- More tightly packed silica bed
- Homogeneous packing
- Better separation

SiliaSep Flash Cartridges
Today, various manufacturers offer pre-packed flash cartridges, but performance and quality varies. SiliCycle supplies pre-packed columns offered under the brand name of SiliaSep Flash Cartridges.
SiliaSep offers superior performances over competitive cartridges. They are available in two silica gel grades (40-63 & 15-40 microns) and with various functionalities (reversed & normal phases, ion exchangers and metal scavengers) to meet any purification demand.
SiliaSep Flash Cartridge Design
Types of cartridges
To better suits your needs, the SiliaSep flash cartridges family includes six types of cartridges that are compatible with different type of instruments:
- SiliaSep (Isco™, Biotage™, Analogix™& Reveleris™ Compatible)
- SiliaSep HP (Isco™, Biotage™, Analogix™ & Reveleris™ Compatible - High Performance)
- SiliaSep XL (Isco CombiFlash Companion XL Compatible)
- SiliaSep BT (Biotage™ i Compatible)
- SiliaSep OT (FlashMaster™ Compatible)
Our flash chromatography products offer high levels of performance and reproducibility. The flash media consistently has a tight particle size distribution with low fines and extremely low metal ion content, for more predictable and easier separations.
Using SiliCycle SiliaSep cartridges, you can purify your sample base on different mechanisms depending on the properties or your compound. Because we can provide cartridges packed with our SiliaBond® functionalized silica gel, you can choose exactly the cartridge that will fit your need. The chart below is designed to serve as a guide in sorbent selection by considering the characteristics of you sample.
SiliaSep Ordering Information
For more informations, click on product number links.
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SiliaSep™ Flash Cartridges Silica
SiliaSep flash cartridges offer a superior alternative to the other cartridges available on the market as they present the following characteristics:
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SiliaSep™ Flash Cartridges C18 nec
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
SiliaSep flash C18 cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges C18
Indicated for the purification of medium to high polarity compounds. They provide reproducible purification without the complexity and cost of preparative HPLC.
SiliaSep flash C18 cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Cyano
Versatile cartridges that can be used either as normal or reversed-phase. Indicated for products with intermediate polarity.
SiliaSep flash cyano cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Amine
Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase.
SiliaSep flash amine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges TMA Chloride (SAX)
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.
SiliaSep flash TMA Chloride cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges TMA Acetate nec
Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by catch and release process.
SiliaSep flash TMA Acetate cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Tosic Acid (SCX)
Packed with a strong cation exchanger, they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.
SiliaSep flash propylsulfonic acid cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Diol
Good alternative for difficult separation of low to medium polarity samples. Offer a better retention time compared to normal phase.
SiliaSep flash diol cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Propylsulfonic Acid (SCX-2)
Packed with a strong cation exchanger (SiliaBond® Propylsulfonic Acid), they can be used to fully retain basic compounds for clean-up or to isolate them by catch and release process.
SiliaSep flash propylsulfonic acid cartridges offer a superior alternative to the other cartridges available on the market..
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SiliaSep™ Flash Cartridges Triamine
SiliaSep flash triamine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Diamine
SiliaSep flash diamine cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Thiol
SiliaSep flash thiol cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges TAAcOH
SiliaSep flash TAAcOH cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges TAAcONa
SiliaSep flash TAAcONa cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Thiourea
SiliaSep flash thiourea cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Dimercaptotriazine (DMT)
SiliaSep flash DMT cartridges offer a superior alternative to the other cartridges available on the market.
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SiliaSep™ Flash Cartridges Cysteine
SiliaSep flash cysteine cartridges offer a superior alternative to the other cartridges available on the market .
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SiliaSep™ Flash Cartridges - HP Silica
SiliaSep™ HP flash cartridges are made with the same tubes as the SiliaSep (and consequently present all the same great characteristics) but are packed with small particle size silica gel. They are designed to outperform when there is a specific need, such as very tight separation.





