SiliaPrepX™- Polymeric |

Solid-phase extraction (SPE) is a technique designed for rapid sample preparation and purification prior to chromatographic analysis. You can optimize your SPE protocols by using SiliCycle SiliaPrepX Polymeric SPE Cartridges and Well Plates.
Using SiliaPrepX will guarantee the following:
- High quality products covering a broad spectrum of applications for a wide range of complexe matrices.
- Exceptional lot-to-lot reproducibility.
- High recoveries and yields.
- Very good separation and flow characteristics (high loadability and great elution properties allowing low solvent comsumption and economical analysis).
- No contamination from the matrix (clean extract reducing the ionic suppression and increasing the selectivity for LC-MS/MS applications).
- Exceptional pH stability (1 to 14).
- Excellent packing and storage qualities.
Determination of the Optimal SiliaPrepX Polymeric Phase by a Simple & Logical Method
Follow the simple and logical steps outlined in the flow chart to achieve high recovery, clean extract and determine the optimal SiliaPrepX polymeric phase:
- Determine the classification of the analyte (neutral, acidic or basic compound).
- Determine the pKa of the analyte.
- Select the SiliaPrepX phase.
- Applied the indicated treatment.
- Determine the SPE recovery by LC analysis.

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SiliaPrepX™ HLB Polymeric SPE Cartridges
The SiliaPrepX™ HLB is a wettable copolymer presenting a Hydrophobic-Lipophilic Balance (HLB) permitting a strong retention for neutral, acidic and basic compounds and a high stability in organic silvents.
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SiliaPrepX™ DVB Polymeric SPE Cartridges
The SiliaPrepX™ DVB is a polystyrene-divinylbenzene copolymer presenting a high hydrophobicity used as reversed-phase for extraction of neutral, acidic and basic compounds in viscous matrices.
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SiliaPrepX™ SCX Polymeric SPE Cartridges
The SiliaPrepX™ SCX is a polystyrene-divinylbenzene copolymer functionalized by a strong cation exchanger presenting a high selectivity for acids (pKa 2 - 10). It is highly stable in organic solvents.
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SiliaPrepX™ SAX Polymeric SPE Cartridges
The SiliaPrepX™ SAX is a polystyrene-divinylbenzene copolomer functionalized by a strong anion exchanger presenting a high selectivity for acids (pKa 2 - 8). It is highly stable in organic solvents.
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SiliaPrepX™ WCX Polymeric SPE Cartridges
The SiliaPrepX™ WCX is a polystyrene-divinylbenzene copolymer functionalized by a weak cation exchanger used to catch and release strong basic compounds (pKa >10). It is highly stable in organic solvents.
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SiliaPrepX™ WAX Polymeric SPE Cartridges
The SiliaPrepX™ WAX is a polystyrene-divinylbenzene copolymer functionalized by a weak anion exchanger used to catch and release strong acidic compounds (pKa <2). It is highly stable in organic solvents.
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SiliaPrepX™ HLB Polymeric Well Plates
The SiliaPrepX™ HLB is a wettable copolymer presenting a Hydrophobic-Lipophilic Balance (HLB) permitting a strong retention for neutral, acidic and basic compounds and a high stability in organic silvents.
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SiliaPrepX™ DVB Polymeric Well Plates
The SiliaPrepX™ DVB is a polystyrene-divinylbenzene copolymer presenting a high hydrophobicity used as reversed-phase for extraction of neutral, acidic and basic compounds in viscous matrices.
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SiliaPrepX™ SCX Polymeric Well Plates
The SiliaPrepX™ SCX is a polystyrene-divinylbenzene copolymer functionalized by a strong cation exchanger presenting a high selectivity for acids (pKa 2 - 10). It is highly stable in organic solvents.
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SiliaPrepX™ SAX Polymeric Well Plates
The SiliaPrepX™ SAX is a polystyrene-divinylbenzene copolomer functionalized by a strong anion exchanger presenting a high selectivity for acids (pKa 2 - 8). It is highly stable in organic solvents.
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SiliaPrepX™ WCX Polymeric Well Plates
The SiliaPrepX™ WCX is a polystyrene-divinylbenzene copolymer functionalized by a weak cation exchanger used to catch and release strong basic compounds (pKa >10). It is highly stable in organic solvents.
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SiliaPrepX™ WAX Polymeric Well Plates
The SiliaPrepX™ WAX is a polystyrene-divinylbenzene copolymer functionalized by a weak anion exchanger used to catch and release strong acidic compounds (pKa <2). It is highly stable in organic solvents.





