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SiliaPrep Silica-based SPE Cartridges & Well Plates

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Reversed-Phases Normal Phases Ion-Exchange Phases Mixed-Mode Phases

Metal Scavengers Fluorinated Phases Specialty Phases

Solid-phase extraction (SPE) is a technique designed for rapid sample preparation and purification prior to chromatographic analysis.

For your convenience, SiliaPrep are available in different formats: cartridges (SiliaPrep SPE Cartridges), and well plates (SiliaPrep 96 Well Plates) with various sorbents (SiliaFlash® and SiliaBond®), and bed weight (up to 20 grams). The well plates are used in high throughput combinatorial chemistry, drug discovery and screening, and metabolism pharmacokinetics applications and for automated method as multiprobe approach.

By using SiliaPrep products you will generate higher purity samples and reduce the number of false positives in your screening, resulting in higher quality data. All the SiliaPrep are packed with sorbents based on the fines-free SiliaFlash silica gel.

Using SiliaPrep will guarantee the following:

  • High quality and wide variety of SiliaBond sorbents available
  • Very good separation (very tight particle size distribution and no fines)
  • High recoveries and yields
  • Less time and solvent spent conditioning the sorbent
  • No silica contamination of your final product
  • Reproducible flow rate from lot-to-lot
  • Excellent packing and storage qualities

 

 NEW  Learn more about using our SiliaPrep SPE products with our Suggested SPE protocols for various analytes & matrices

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  1. SiliaPrep 96 Well Plates Amine (WAX), 40 - 63 µm, 60 Å (96W-R52030B)

    SiliaPrep 96 Well Plates Amine (WAX), 40 - 63 µm, 60 Å (96W-R52030B)

    SiliaPrep Amine is a weak anion exchanger sorbent used in replacement of SAX for strong anions to avoid irreversible retention. Can also be employed as a metal scavenger and in normal phase conditions.
  2. SiliaPrep 96 Well Plates, Amine (WAX) nec, 40 - 63 µm, 60 Å (96W-R52130B)

    SiliaPrep 96 Well Plates, Amine (WAX) nec, 40 - 63 µm, 60 Å (96W-R52130B)

    When used at pH ≤ 7.8, Amine is protonated and may be used as a weak anion exchanger (WAX).
  3. SiliaPrep 96 Well Plates, Carbonate, 40 - 63 µm, 60 Å (96W-R66030B)

    SiliaPrep 96 Well Plates, Carbonate, 40 - 63 µm, 60 Å (96W-R66030B)

    SiliaPrep Carbonate (or Si-CO3) is the silica bound equivalent of tetramethyl ammonium carbonate. It can be used as a general base to quench a reaction, to free base amines in their ammonium salt form and to scavenge acids, boronic acids and acidic phenols, including HOBt, which is widely used in amide coupling reactions.
  4. SiliaPrep 96 Well Plates, Carboxylic Acid (WCX), 40 - 63 µm, 60 Å (96W-R70030B)

    SiliaPrep 96 Well Plates, Carboxylic Acid (WCX), 40 - 63 µm, 60 Å (96W-R70030B)

    SiliaPrep Carboxylic Acid is a weak cation exchanger sorbent (WCX) used to extract strong basic compounds
  5. SiliaPrep 96 Well Plates, Carboxylic Acid (WCX) nec, 40 - 63 µm, 60 Å (96W-R70130B)

    SiliaPrep 96 Well Plates, Carboxylic Acid (WCX) nec, 40 - 63 µm, 60 Å (96W-R70130B)

    Standard SiliaPrep 96 Well Plates are available in 2 mL with different bed weight up to 200 mg. Various sorbents are available and are divided into several sections based on sorbent characteristics.
  6. SiliaPrep 96 Well Plates, Cyano (CN), 40 - 63 µm, 60 Å (96W-R38030B)

    SiliaPrep 96 Well Plates, Cyano (CN), 40 - 63 µm, 60 Å (96W-R38030B)

    SiliaPrep Cyano is a moderate polar sorbent used as reversed-phase (less hydrophobic than C18 and C8 phases) and normal phase (less polar compared to silica) to extract acidic, neutral, basic compounds from aqueous solutions.
  7. SiliaPrep 96 Well Plates, Triethylamine (WAX-2), 40 - 63 µm, 60 Å (96W-R76530B)

    SiliaPrep 96 Well Plates, Triethylamine (WAX-2), 40 - 63 µm, 60 Å (96W-R76530B)

    SiliaPrep Triethylamine (WAX-2) is a weak anion exchanger that can be used in replacement of SAX and SAX-2 for strong anions to avoid irreversible retention. This phase presents a slightly lower capacity and a moderate non polar character due to the alkyl chain on the amino function. Moreover, it can be employed as metal scavenger and in normal phase conditions.
  8. SiliaPrep 96 Well Plates, Diol nec, 40 - 63 µm, 60 Å (96W-R35030B)

    SiliaPrep 96 Well Plates, Diol nec, 40 - 63 µm, 60 Å (96W-R35030B)

    SiliaPrep Diol nec is a moderate polar sorbent presenting neutral character used to extract polar compounds from non-polar solvents, structural isomers. Alternative to silica when the acidic character is problematic.
  9. SiliaPrep 96 Well Plates, Pentafluorophenyl (PFP), 40 - 63 µm, 60 Å (96W-R67530B)

    SiliaPrep 96 Well Plates, Pentafluorophenyl (PFP), 40 - 63 µm, 60 Å (96W-R67530B)

    SiliaPrep Pentafluorophenyl is a fluorous sorbent used to separate fluorinated molecules and non-fluorinated ones. The electron density presents fluorinated aromatic ring which affords an enhancement in the retention of conjugated and aromatic ring-containing due to the desirable pi-pi interactions. Excellent alternative of the C18 when the C18 presents a selectivity problem.
  10. SiliaPrep 96 Well Plates, Fluorochrom, 40 - 63 µm, 60 Å (96W-R63730B)

    SiliaPrep 96 Well Plates, Fluorochrom, 40 - 63 µm, 60 Å (96W-R63730B)

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  11. SiliaPrep 96 Well Plates, Phenyl, 40 - 63 µm, 60 Å (96W-R34030B)

    SiliaPrep 96 Well Plates, Phenyl, 40 - 63 µm, 60 Å (96W-R34030B)

    SiliaPrep Phenyl is a non-polar sorbent used to extract compounds from aqueous solution and presents high selectivity for aromatics compounds compared to the other non-polar phases caused by the pi-pi interactions.
  12. SiliaPrep 96 Well Plates TMA Chloride nec (SAX), 40 - 63 µm, 60 Å (96W-R66530B)

    SiliaPrep 96 Well Plates TMA Chloride nec (SAX), 40 - 63 µm, 60 Å (96W-R66530B)

    SiliaPrep TMA Chloride (SAX) is a strong anion exchanger sorbent positively charged under all conditions used to extract acid molecules (pKa 3-5).
  13. SiliaPrep 96 Well Plates, TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (96W-R66430B)

    SiliaPrep 96 Well Plates, TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (96W-R66430B)

    SiliaPrep TMA Acetate (SAX-2) is a strong anion exchanger sorbent with a low selectivity acetate counter ion already in place. This sorbent retains more favorably acidic compounds with pKas <5, such as carboxylic acid.
  14. SiliaPrep 96 Well Plates Tosic Acid (SCX), 40 - 63 µm, 60 Å (96W-R60530B)

    SiliaPrep 96 Well Plates Tosic Acid (SCX), 40 - 63 µm, 60 Å (96W-R60530B)

    SiliaPrep Tosic Acid (SCX) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  15. SiliaPrep 96 Well Plates, Tosic Acid (SCX) nec, 40 - 63 µm, 60 Å (96W-R60430B)

    SiliaPrep 96 Well Plates, Tosic Acid (SCX) nec, 40 - 63 µm, 60 Å (96W-R60430B)

    SiliaPrep Tosic Acid is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  16. SiliaPrep 96 Well Plates, Tridecafluoro, 40 - 63 µm, 60 Å (96W-R63530B)

    SiliaPrep 96 Well Plates, Tridecafluoro, 40 - 63 µm, 60 Å (96W-R63530B)

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  17. SiliaPrep 96 Well Plates, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (96W-R51230B)

    SiliaPrep 96 Well Plates, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (96W-R51230B)

    SiliaPrep Propylsulfonic Acid (SCX-2) is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  18. SiliaPrep 96 Well Plates Propylsulfonic Acid (SCX-2) nec, 40 - 63 µm, 60 Å (96W-R51430B)

    SiliaPrep 96 Well Plates Propylsulfonic Acid (SCX-2) nec, 40 - 63 µm, 60 Å (96W-R51430B)

    SiliaPrep Propylsulfonic Acid nec is a strong cation exchanger and maintains a negative charge throughtout the pH scale. The most common use is a strong cation exchanger for the amine and basics molecules "catch and release" purification technique in SPE cartridges.
  19. SiliaPrep 96 Well Plates, Mixed-Mode C8/SAX, 40 - 63 µm, 60 Å (96W-R022830B)

    SiliaPrep 96 Well Plates, Mixed-Mode C8/SAX, 40 - 63 µm, 60 Å (96W-R022830B)

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  20. SiliaPrep 96 Well Plates, Mixed-mode C8/SCX-2, 40 - 63 µm, 60 Å (96W-R028030B)

    SiliaPrep 96 Well Plates, Mixed-mode C8/SCX-2, 40 - 63 µm, 60 Å (96W-R028030B)

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  21. SiliaPrep 96 Well Plates, Mixed-Mode C8/SCX, 40 - 63 µm, 60 Å (96W-R023830B)

    SiliaPrep 96 Well Plates, Mixed-Mode C8/SCX, 40 - 63 µm, 60 Å (96W-R023830B)

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  22. SiliaPrep Mixed-Mode 96 Well Plates SCX-2/SAX (96W-R802830B)

    SiliaPrep Mixed-Mode 96 Well Plates SCX-2/SAX (96W-R802830B)

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  23. SiliaPrep SPE Cartridges C18 (17%) (SPE-R00230B)

    SiliaPrep SPE Cartridges, C18 (17%), 40 - 63 µm, 60 Å (SPE-R00230B)

    SiliaPrep C18 (17%) is a strongly hydrophobic and non polar sorbent. It is very useful for the extraction of acidic / neutral / basic compounds from aqueous solutions, organic compounds from water and drugs & metabolites from fluids.
  24. SiliaPrep SPE Cartridges C18 WPD (SPE-R33229G)

    SiliaPrep SPE Cartridges C18 WPD, 37-55μm, 125Å (SPE-R33229G)

    For organic compounds from water, drugs & metabolites from fluids
  25. SiliaPrep 96 Well Plates C18 (17%), 40 - 63 µm, 60 Å (96W-R00230B)

    SiliaPrep 96 Well Plates C18 (17%), 40 - 63 µm, 60 Å (96W-R00230B)

    SiliaPrep C18 (17%) is a strongly hydrophobic and non polar sorbent. It is very useful for the extraction of acidic / neutral / basic compounds from aqueous solutions, organic compounds from water and drugs & metabolites from fluids.
  26. SiliaPrep 96 Well Plates, C18 WPD, 37 - 55 µm, 125 Å (96W-R33229G)

    SiliaPrep 96 Well Plates, C18 WPD, 37 - 55 µm, 125 Å (96W-R33229G)

    For organic compounds from water, drugs & metabolites from fluids
  27. SiliaPrep 96 Well Plates, C18 nec, 40 - 63 µm, 60 Å (96W-R35530B)

    SiliaPrep 96 Well Plates, C18 nec, 40 - 63 µm, 60 Å (96W-R35530B)

    SiliaPrep C18 nec (17%) is a non-polar sorbent similar to SiliaPrep C18 but presents higher retention and polar selectivity for basic compounds.
  28. SiliaPrep Mixed-Mode SPE Cartridges DMT/Imidazole, 100 mg, 6 mL, 40 - 63 µm, 60 Å (SPM-R1079930B-06C)

    SiliaPrep Mixed-Mode SPE Cartridges DMT/Imidazole, 100 mg, 6 mL, 40 - 63 µm, 60 Å (SPM-R1079930B-06C)

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  29. SiliaPrep SPE Cartridges Dual-Layer, SAX nec/Diamine, 500 mg each, 6 mL (SP2-R280730B-06P)

    SiliaPrep SPE Cartridges Dual-Layer, SAX nec/Diamine, 500 mg each, 6 mL (SP2-R280730B-06P)

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  30. SiliaPrep SPE Cartridges Cysteine (SPE-R80530B)

    SiliaPrep SPE Cartridges, Cysteine (SPE-R80530B)

    Best scavenger for: Cd, Fe, Ir, Os, Ru, Sc & Sn / Good scavenger for: Ca, Cr, Cs, Cu, La, Mg, Pd, Pt, Rh, Se & Zn
  31. SiliaPrep SPE Cartridges Imidazole (SPE-R79230B)

    SiliaPrep SPE Cartridges, Imidazole (SPE-R79230B)

    Best scavenger for: Cd, Co, Cu, Fe, Ir, Li, Mg, Ni, Os, W & Zn / Good scavenger for: Cr, Pd & Rh
  32. SiliaPrep Dual Layer SPE Cartridges, PAH (SP2-R0610030B)

    SiliaPrep Dual Layer SPE Cartridges, PAH (SP2-R0610030B)

    SiliaPrep PAH has been optimized for typical environmental samples, to specifically extract PAHs from waste waters.
  33. SiliaPrep Dual Layer SPE Cartridges, PCB (SP2-R00650030B)

    SiliaPrep Dual Layer SPE Cartridges, PCB (SP2-R00650030B)

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  34. SiliaPrep SPE Cartridges Silica WPD, 37 - 55 µm, 125 Å (SPE-R10029G)

    SiliaPrep SPE Cartridges Silica WPD, 37 - 55 µm, 125 Å (SPE-R10029G)

    For various compounds from non-polar solvents, structural isomers
  35. SiliaPrep 96 Well Plates Mixed-Mode, C8/TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (96W-R026630B)

    SiliaPrep 96 Well Plates, Mixed-Mode C8/SAX-2 nec, 40 - 63 µm, 60 Å (96W-R026630B)

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  36. SiliaPrep 96 Well Plates, Imidazole, 40 - 63 µm, 60 Å (96W-R79230B)

    SiliaPrep 96 Well Plates, Imidazole, 40 - 63 µm, 60 Å (96W-R79230B)

    Best scavenger for: Cd, Co, Cu, Fe, Ir, Li, Mg, Ni, Os, W & Zn / Good scavenger for: Cr, Pd & Rh
  37. SiliaPrep SPE Cartridges Florisil LP, 75 - 150 µm, 100 Å (SPE-AUT-0014LP)

    SiliaPrep SPE Cartridges Florisil LP, 75 - 150 µm, 80 Å (SPE-AUT-0014LP)

    SiliaPrep Florisil is a polar sorbent presenting basic character used to extract non-polar to moderate polar compounds from non-polar solvents. This sorbent contain magnesium ion which allows retention for chlorinated pesticides, polychlorinated biphenyl and polysaccharides.
  38. SiliaPrep 96 Well Plate, Silica WPD, 37 - 55 µm, 125 Å (96W-R10029G)

    SiliaPrep 96 Well Plate, Silica WPD, 37 - 55 µm, 125 Å (96W-R10029G)

    For various compounds from non-polar solvents, structural isomers
  39. SiliaPrep 96 Well Plate, CleanENVI, 40 - 63 µm, 60 Å (96W-R31930B)

    SiliaPrep 96 Well Plate, CleanENVI, 40 - 63 µm, 60 Å (96W-R31930B)

    SiliaPrep CleanENVI phase has been optimized for typical environment samples according to the EPA regulations.
  40. SiliCycle Sample Preparation Solutions

    SiliCycle Sample Preparation Solutions

    Brochure, 60 pages. SiliCycle's Sample Preparation products: SPE cartridges (silica & polymeric) and micro SPE
  41. SiliaPrep SPE Cartridges, Dual-Layer, Na2SO4/Florisil LP, 2 g each (SP2-AUT-0614)

    SiliaPrep SPE Cartridges, Dual-Layer, Na2SO4/Florisil LP, 2 g each (SP2-AUT-0614)

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  42. SiliaPrep Mixed-Mode SPE Cartridges, SCX/SAX nec, 40 - 63 µm, 60 Å (SPM-R283830B)

    SiliaPrep Mixed-Mode SPE Cartridges, SCX/SAX nec, 40 - 63 µm, 60 Å (SPM-R283830B)

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  43. SiliaPrep 96 Well Plates, Thiol, 40 - 63 µm, 60 Å (96W-R51030B)

    SiliaPrep 96 Well Plates, Thiol, 40 - 63 µm, 60 Å (96W-R51030B)

    SiliaMetS® Thiol (Si-Thiol) is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger: Ag, Hg, Os, Pd & Ru. Good scavenger: Cu, Ir, Pb, Rh & Sn.
  44. SiliaPrep 96 Well Plates, Dimercaptotriazine (DMT), 40 - 63 µm, 60 Å (96W-R79030B)

    SiliaPrep 96 Well Plates, Dimercaptotriazine (DMT), 40 - 63 µm, 60 Å (96W-R79030B)

    SiliaMetS® DMT is the silica-bound equivalent of 2,4,6 - trimercaptotriazine (trithiocyanuric acid, TMT). It is a versatile metal scavenger for a variety of metals and the preferred metal scavenger for ruthenium catalysts and hindered Pd complexes (i.e. Pd(dppf)Cl2). Best scavenger: Ir, Ni, Os, Pd, Pt, Rh, Se & Ru. Good scavenger: Cd, Co, Cu, Fe, Sc & Zn.

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Amine (NH2): a very versatile sorbent used for various applications
SiliaSep PREMIUM - Flash Cartridges packed with Spherical Silica
E-PAK® - Fixed Bed Flow-through Purification Cartridges

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