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SiliaPlate - Thin Layer Chromatography (TLC)

SiliCycle is the partner of choice for your purification
and chromatography needs.

  • Optimize separation conditions by using the same silica gel as in your flash columns and cartridge;
  • Made with an extra hard layer that ensures the plates won’t lose silica on robbing and heating;
  • Lot-to-lot and layer-to-layer reproducibility guaranteed by the consistent thickness of our SlicaPlate;
  • Made with a unique Gypsum binder and UV indicator for direct visualization;
  • Maximal separation performance ensured by dense coating and narrow particle size distribution;
  • Small quantity of compound required and high sample throughput capability (up to 20 samples simultaneously);
  • Wide range of sizes, backings and chemistries to suit wide range of application needs;
  • Suitable for quality testing, residue analysis, drug monitoring, reactions follow-up, in-process control, metabolism studies etc.

SiliCycle SiliaPlate - TLC plates

Types of SiliaPlate Backings

Glass

Advantages

  • High heating stability;
  • High chemical resistance;
  • Transparent.
SiliCycle SiliaPlate - glass backed TLC plates

Inconveniences

  • Thick;
  • High fragility;
  • Impossible scissors cutting;
  • Cannot be stored in lab notebook.
  • High weight.

Aluminum

Advantages

  • Thin;
  • Low weight;
  • High heating stability;
  • Low fragility;
  • Easy scissors cutting;
  • Can be stored in lab notebook.
SiliCycle SiliaPlate - aluminum backed TLC plates

Inconveniences

  • Low chemical resistance;
  • Opaque.

Plastic

Advantages

  • Thin;
  • Low fragility;
  • Possible scissors cutting;
  • High chemical resistance;
  • Can be stored in lab notebook.
SiliCycle SiliaPlate - plastic backed TLC plates

Inconveniences

  • Opaque.
  • Medium weight;
  • Heating stability up to 175°C.

Plate Types

SiliCycle offers different types of plates for thin layer chromatography applications: classical TLC, high performance TLC (also called HPTLC) and preparative TLC (PLC). The plate types are selected based on the type of analysis required and the available budget.

Differences between classical TLC, HPTLC and PLC
Properties Classical TLC HPTLC Preparative PLC
Application Quick, inexpensive, flexible and portable separations Highly sophisticated separation problems, complex samples Purification on a TLC plate
Analysis Qualitative Qualitative & Quantitative Quantitative
Detection UV
Stains
Instrumented analysis (use of scanners for detection) UV
Price Lower prices than HPTLC Higher prices than TLC -
Distribution
[Mean Particle Size]
5 - 20 µm
[10 - 12 µm]
4 - 8 µm
[5 - 6 µm]
5 - 40 µm
[25 µm]
Layer Thickness 250 µm 200 µm 0.5 mm, 1 mm, 2 mm
Typical Sample Volume 1 – 5 µL 0.1 – 0.5 µL 5 – 20 µL

SiliaPlate Ordering Information

Analytical TLC Plates
SiliCyle PN Product Name Plate Size (cm) Thickness (µm) Plates per box
Analytical SiliaPlate Glass
TLG-R10011B-423 Micro SiliaPlate Glass 5 x 20 250 25
TLG-R10014B-124 Micro SiliaPlate Glass 2.5 x 7.5 250 100
TLG-R10011B-624 Micro SiliaPlate Glass 2.5 x 10 250 100
TLG-R10014B-527 SiliaPlate Glass 5 x 10 250 200
TLG-R10014B-424 SiliaPlate Glass 5 x 20 250 100
TLG-R10011B-723 SiliaPlate Glass 10 x 20 250 25
TLG-R10014B-323 NEW and Improved - SiliaPlate Glass 20 x 20 250 25
TLG-R10014BK-323 SiliaPlate Glass,
Optimized for KMnO4, Vanillin and Anisaldehyde revelation revelation
20 x 20 250 25
Can’t choose between our 2 models of 20x20 cm TLC plates ? Let us help !
> Difference between TLG-R10014B-323 and TLG-R10014BK-323 SiliaPlate TLC Plates
Scored Analytical SiliaPlate Glass
TLGSR10011B-423 SiliaPlate Glass (scored) 5 x 20
(scored to 8 plates 2.5 x 5 cm)
250 25
Channeled Analytical SiliaPlate Glass (with Preadsorbent Zone)
TLGCZ-R10011B-323 Channeled SiliaPlate Glass 20 x 20 250 25
SiliaPlate Al (Aluminum)
TLA-R10011B-323 SiliaPlate Aluminum 20 x 20 200 25
SiliaPlate Al C18 (Aluminum)
TLA-R30411B-303 SiliaPlate Aluminum C18 20 x 20 200 25
SiliaPlate Pl (Plastic)
TLP-R10011B-323 SiliaPlate Plastic 20 x 20 200 25
HPTLC Plates
SiliCyle PN Product Name Plate Size (cm) Thickness (µm) Plates per box
SiliaPlate HPTLC silica with Glass Backing
HPTLG-R10011B-1010 SiliaPlate Silica HPTLC 10 x 10 150 25
HPTLG-R10011B-2020 SiliaPlate Silica HPTLC 20 x 20 150 25
HPTLGSR10011B-1010 Scored SiliaPlate Silica HPTLC 10 x 10 (to 5 x 5) 150 25
Functionalized C18 SiliaPlate HPTLC
TLG-R30411B-213 SiliaPlate C18 HPTLC 10 x 10 150 25
TLG-R30411B-303 SiliaPlate C18 HPTLC 20 x 20 150 25
Functionalized C8 SiliaPlate HPTLC
TLG-R31011B-203 SiliaPlate C8 HPTLC 10 x 10 150 25
TLG-R31011B-303 SiliaPlate C8 HPTLC 20 x 20 150 25
Functionalized C2 SiliaPlate HPTLC
TLG-R32611B-203 SiliaPlate C2 HPTLC 10 x 10 150 25
TLG-R32611B-303 SiliaPlate C2 HPTLC 20 x 20 150 25
SiliaPlate NH2 (Amine) HPTLC
TLG-R52011B-203 SiliaPlate NH2 HPTLC 10 x 10 150 25
TLG-R52011B-303 SiliaPlate NH2 HPTLC 20 x 20 150 25
SiliaPlate CN (Cyano) HPTLC
TLG-R38011B-203 SiliaPlate CN HPTLC 10 x 10 150 25
TLG-R38011B-303 SiliaPlate CN HPTLC 20 x 20 150 25
SiliaPlate Diol HPTLC
TLG-R35011B-203 SiliaPlate Diol HPTLC 10 x 10 150 25
TLG-R35011B-303 SiliaPlate Diol HPTLC 20 x 20 150 25
SiliaPlate Ag (Silver Nitrate 10% impregnated) HPTLC
TLG-R23511B-423 SiliPlate Aluminum C18 5 x 20 150 25
TLG-R23511B-303 SiliPlate Plastic 20 x 20 150 25
Preparative TLC Plates
SiliCyle PN Product Name Plate Size (cm) Thickness (µm) Plates per box
SiliaPlate Prep (Glass Preparative)
TLG-R10011B-333 SiliaPlate Prep 20 x 20 500 25
TLG-R10011B-341 SiliaPlate Prep 20 x 20 1,000 25
TLG-R10011B-350 SiliaPlate Prep 20 x 20 2,000 12
TLG-R10011B-353 SiliaPlate Prep 20 x 20 2,000 25
Scored SiliaPlate Prep (Glass Preparative)
TLGSR10011B-333 SiliaPlate Prep Glass (scored to 5 x 20 cm) 20 x 20 500 25
TLGSR10011B-341 SiliaPlate Prep Glass (scored to 5 x 20 cm) 20 x 20 1,000 25
TLGSR10011B-353 SiliaPlate Prep Glass (scored to 5 x 20 cm) 20 x 20 2,000 25
SiliaPlate Prep C18 (Glass Preparative)
TLG-R30411B-341 SiliaPlate C18 Prep Glass 20 x 20 1000 15