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SiliaBond® Isocyanate

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SiliaBond® Isocyanate

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Product Number Quantity  
R50030B-5g 5 g

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R50030B-10g 10 g

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R50030B-25g 25 g

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R50030B-50g 50 g

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R50030B-100g 100 g

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R50030B-250g 250 g

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R50030B-500g 500 g

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R50030B-1kg 1 kg

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Product Description

Specifications


 
  • Details

    SiliaBond® Isocyanate (Si-ISO) is a versatile scavenger for nucleophiles. It readily scavenges amines, thiols, thiolates, alkoxides, and acidic phenols. Loading is determined by the removal of benzylamine in hexane at room temperature. Si-ISO has been used to scavenge amines in a “cap-tag” methodology for oligosaccharide preparation by automated solid phase synthesis1 and in the preparation of 2,5-diketopiperazines and 1,4-benzodiazepine-2,5-diones.2

    Silica supported isocyanate has superior reactivity in a broader range of solvents when compared to polymer-based materials.

    PRODUCT SPECIFICATIONS

    MSDS-R50030B

    SILIABOND TYPICAL REACTIONS
    SiliaBond Reagents & Oxidants Typical Reactions Selection Table

    APPLICATION NOTE
    General : Click here

    RELATED PUBLICATIONS

    1. Angew. Chem. Int. Ed., 40 (2001) 4433
    2. Org. Lett., 4 (2002) 1167
  • Additional Information

    Array Isocyanate
    Family / Formats SiliaBond® (Functionalized Silicas)
    Particle Size 40-63 µm / 230-400 mesh
    Pore Size 60 Å
    Endcapping Endcapped
    Storage Condition Keep dry and cool (<8°C)