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  1. Simple and Effective Removal of Boronic Acids after Newly Reported Mutagenic Activity

    Simple and Effective Removal of Boronic Acids after Newly Reported Mutagenic Activity

    White Paper (3 pages) - Up to very recently, boronic acids had always been reported as lacking apparent toxicity, mutagenic activity or in vivo instability issues. New studies have raised objections about this safe toxicological profile, both based on experimental and clinical data. SiliCycle's SiliaBond DEAM and Diol have shown to be powerful and very effective scavengers for the removal of boronic acids.
  2. Get ready for the new ICH-Q3D Heavy Metal Regulation

    Get ready for the new ICH-Q3D Heavy Metal Regulation

    For almost two years now, the International Conference on Harmonisation (ICH) has been working on its Q3D guidelines for metal elemental impurities in new drugs and new formulations containing known ingredients. After many revisions and improvements, the final version or the Q3D guidelines was finally accepted and signed off, hence requiring that the entire manufacturing industry and supply chain follow these regulations.

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