Follow SiliCycle on Facebook Follow SiliCycle on Twitter Follow SiliCycle on LinkedIn Watch our videos on Youtube

Frequently Asked Questions about Metal & Organic Scavengers

> back to FAQ main page

Here you will find questions and answers about our metal scavengers (SiliaMetS) and organic scavengers (SiliaBond), in their various applications and formats (bulk or packaged as E-PAK Cartridges).

If you still have questions, please contact our technical support department: [email protected].

 

Scavengers Overview

What are metal scavengers?

What is a supported scavenger?

What are the advantages of choosing a silica-based product over a polymer-based one?

What is the shelf life of SiliaMetS and can it be used once the shelf life expired?

Can I use your scavengers in flow type applications?

Can Potentially Genotoxic Impurities (PGI) be removed by SiliaMetS metal scavengers and/or SiliaBond organic scavengers?

Do SiliaMetS scavengers leach?

Does SiliCycle have a solution to freebase amines from their TFA salt form?

Do you have customers in the pharma industry who have already used SiliaMetS?

 

Scavengers Availability

Are the scavengers available at metric ton quantities?

What other formats are your scavengers available in?

Are you a distributor or a manufacturer of scavengers?

How do you maintain batch-to-batch product quality?

 

Scavengers Selection

How to choose a scavenger?

Why are screening tests important regarding the selection of a metal scavenger?

How much and how long is the screening service?

 

Scavengers Preparation

What is molecular loading and how do you determine the molecular loading of a SiliaMetS metal scavenger?

How do you calculate how much scavenger to use?

I have a significant quantity of metal to be removed from my mixture, will the 4-8 equivalents of SiliaMetS recommended for a typical initial screening suffice?

What are the densities of the SiliaBond organic scavengers & SiliaMetS metal scavengers?

Do SiliaMetS require an activation step prior to their use?

 

Use of Scavengers

Can I just dump your scavenger into a reactor?

What kind of solvent would be preferred with SiliaMetS and SiliaBond scavengers?

What is the scavenging reaction time?

At what temperature should scavengers be used?

What is the thermal stability of SiliaMetS Thiol?

What is the mechanical stability of SiliaMetS metal scavengers?

At what pH should the scavenging in aqueous solution be performed?

What will happen to my scavenger if I do not work in the recommended pH scale (between 2 and 10)?

 

Post-Scavenging

Can the metal scavenged be recovered?

How do you clean the reactors after using scavengers?

How should I test my reactor to determine if I removed all of your scavenger?

 

Scavengers Documentation & Regulatory Aspects

What documents are routinely provided to customers?

Do you provide an SOP for used scavengers?

Can SiliCycle help with regulatory support?

 

E-PAK Cartridges for flow-through scavenging

What are the different E-PAK cartridge sizes available and what are the typical pressure and flow rate for each one?

Can we recirculate a solution several times in an E-PAK cartridge or is it single pass only?

What are the maximum pressure and temperature at which the E-PAK can operate?

What is the recommended pH range when using the E-PAK cartridges?

What is the chemical compatibility of the E-PAK cartridges?

Do you provide a Certificate of Analysis (CoA) for the E-PAK cartridges?

How to select the appropriate E-PAK cartridge size?

Which carbon should I select for my purification?

What is the housing material?

What inlet and outlet fittings are required for the housings?

What is the pressure rating for the housing?

What is the temperature rating required for the housing?

 

> back to FAQ main page

2 Item(s)

Set Descending Direction
per page

List  Grid 

  1. SiliCycle range of silica-based scavengers for the removal of metal and/or organic compounds

    Choosing your metal & organic scavenging solution

    Poster - Helps to choose among SiliCycle's unparalleled range of Metal and Organic Scavengers, SiliaMetS® and SiliaBond®.
  2. Solutions For Scavenging of Metal & Organic Impurities (BROSCA)

    Solutions for Scavenging of Metal and Organic Impurities (BROSCA)

    Brochure, 28 pages. Product lines: SiliaMetS Metal Scavengers, SiliaBond Organic Scavengers and E-PAK Fixed Bed Flow Purification Cartridges

2 Item(s)

Set Descending Direction
per page

List  Grid