How to purify your API from organic contaminants?
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Two Ways SiliaBond Organic Scavengers can help you purify your API from organic contaminants
Method 1: Direct scavenging of the undesired compound to isolate the API
- Silica is bound with a functional group, that will specifically react with a product : either excess reagents (unreacted) or impurities.
- The API is recovered by simple filtration as demonstrated on the following scheme:
Method 2: Catch and release of the API
SiliaBond scavenger is packed in a SPE cartridge:
- Conditioning step: with six to ten hold-up volumes of solvent
- Loading step: API is loaded and trapped onto the cartridge bed
- Washing step: cartridge is washed to filter excess reagents and / or other impurities
- Elution step: API is eluted, recovered and purified
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