The pH can increase the retention of some ionizable compounds. However, some products can become hydrolyzed or rearranged when in contact with acidic silica. A neutral pH, with a range between 6.5 and 7.5, is the most important factor in determining the reliability and inert behavior of the silica. This pH test involves suspending the silica gel in pure water (5 % w/w<3em>).
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