
How to improve a high-value ingredient

The technology associates your high-value ingredient with scientifically selected silicas to form versatile micron-sized spherical particles.
The resulting composite material grants increased stability, controlled release, easier formulability and proprietary competitive advantages to your original volatile or active.
in silica™ aims to enable breakthrough cosmetics, perfumes and drugs.
A glimpse into the (secret) in silica™ process
- You provide the ingredient or mixture.
- SiliCycle adapts the process according to your purpose and specifications and generates optimal sphere-shaped composite material (surface polarity, pore size, particle size, load etc.)
- Your ingredient, sequestered in silica microspheres is promptly shipped to you, along with characterization data.
- The improved ingredient is yours to be tested, formulated, commercialized.
Selected Attributes
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in silica™ can improve sensitive ingredients, volatiles, essential oils, synthetic fragrances, vitamins and other hydrophobic actives (ex : retinol) with:
- protection against degradation ;
- slow release for increased safety and efficacy (progressive desorption, indirect contact) ;
- flexibility in formulation of unstable, oxidable or viscous ingredients (incorporating lipophilic actives in aqueous formulations) ;
- modulated desorption for novel olfactory experiences (variation in duration, intensity and desorption order) ;
- ingredient's integrity (no heating involved) ;
- cost-efficiency gains (less material for desired activity level) ;
- regulation-compatible material, process and products.
Have a look

The micron-sized particles show a neat, spherical morphology, without nano debris.

The ingredient creates its own three-dimensional pore network during emulsion.

The end-of-process composite material is a fine and silky powder. Other ready-to-formulate forms available on demand.
Degradation Kinetics - Retinol
Degradation Kinetics (air, light & ambiant temperature)
Degradation Kinetics (air, light & 40° Celcius))
For any information, contact insilica@silicycle.com
Desorption Kinetics - Essential Oil
Comparaison of D-Limonene free (HEEN) vs sequestered in in silica™ microspheres shows that desorption kinetics slowed down with in silica™ Technologies ; nearly 40% more of D-Limonene in the sequestrated oil.

Surface Polarity Control
The external surface can be optimized to create particles with a high or low dispersibility in water following the application needs.
Option 1 : Internal surface hydrophobic / external surface hydrophobic
Option 2 : Internal surface hydrophobic / external surface hydrophilic (see pictures)
Blue coloration of the essential oil sequestrated in the microspheres :




Integrity of Composition
Variable Volatility
1. A complex mixture of volatile terpenes (Black Spruce essential oil - HEEN) is sequestered in in silica™ particles.
2. The presence of twelve compounds was studied. The complex mixture is entirely sequestered in silica particles.
Multiple Chemical Groups
1. A homemade mixture of highly-different compounds is sequestered in in silica™ particles.
Compound | Family | Vapor pressure at 20°C in mmHg |
---|---|---|
Geraniol | alchool | 0.2 |
Terpinolene | terpene | 0.5 |
Bornylacetate | ester | 0.6 |
Benzaldehyde | aldehyde | 1 |
1,8 cineol | ether | 1.65 |
Alpha pinene | terpene | 3 |
Isoamylacetate | ester | 4 |
2. The complex ingredient is entirely sequestered in silica particles.