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SiliaBond®- Amide Coupling Reagents

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  1. SiliaBond Dichlorotriazine (DCT) (R52230B)

    SiliaBond Dichlorotriazine (DCT) (R52230B)

    Amide bond formation is certainly among the most common chemical transformation in organic synthesis. This explains the diversity of possible reaction pathways and reagents available on the market. SiliCycle is part of this trend and this is why we have developed the bound equivalent of 2,4,6-trichloro-1,3,5-triazine(cyanuric chloride), SiliaBond® Dichlorotriazine (Si-DCT).
  2. SiliaBond Carbodiimide (DCC) (R70530B)

    SiliaBond Carbodiimide (DCC) (R70530B)

    SiliaBond® Carbodiimide (Si-DCC) is a bound neutral carbodiimide that may be used for the synthesis of amides, esters, and activated esters.
  3. SiliaBond Ethyl Carbodiimide (EDC) (R70630B)

    SiliaBond Ethyl Carbodiimide (EDC) (R70630B)

    SiliaBond® Ethyl-Dimethylaminopropyl Carbodiimide (Si-EDC) reacts in a similar fashion to SiliaBond Carbodiimide (Si-DCC). The advantage of Si-EDC is this new reagent greatly simplifies the work up procedure of the reactions since a simple filtration is all that takes to remove the unwanted side product of the amides formation (urea).
  4. SiliaBond Reagent Kit (K32230B), including: Carbodiimide ; Cyanoborohydride ; Dichlorotriazine ; DMAP ; EDC ; HOBt

    SiliaBond Reagent Kit (K32230B)

    Includes: Carbodiimide ; Cyanoborohydride ; Dichlorotriazine ; DMAP ; EDC ; HOBt
  5. SiliaBond Hydroxybenzotriazole (HOBt) (R70730B)

    SiliaBond Hydroxybenzotriazole (HOBt) (R70730B)

    SiliaBond® HOBt can be easily activated and should ideally be used with a base such as N,N-diisopropylethylamine in the same condition as in homogeneous solution. Moreover, this supported reagent can be reused a few times without adversely affecting its performance.

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