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SiliaBond Reagents & Oxidants for Knoevenagel Condensation

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  1. SiliaBond Dimethylamine (DMA) (R45030B)

    SiliaBond Dimethylamine (DMA) (R45030B)

    SiliaBond Dimethylamine is a silica bound tertiary amine base that can be used in most applications requiring a tertiary amine, particularly as a HCl sponge. Silica bound ammonium salt by-products are easily separated by filtration. This dimethylamine immobilized on silica gel can be used as a base catalyst in Michael or Knoevenagel reactions. It can also be used as a catalyst for alkane oxidation.
  2. SiliaBond Amine (WAX) nec (R52130B)

    SiliaBond Amine (WAX) nec (R52130B)

    SiliaBond Amine (Si-NH2) is an effective scavenger of acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles. Si-NH2 has been shown to be effective metal scavenger and catalyst for Knoevenagel reactions. SiliaBond Amine is also used in chromatography as normal phase sorbent.
  3. SiliaBond Piperazine (R60030B)

    SiliaBond Piperazine (R60030B)

    SiliaBond Piperazine (Si-PPZ) is a useful deprotecting and scavenging agent for Fmoc and Bsmoc amino protecting groups and as a solid-phase Knoevenagel catalyst. According to the results of a study, Si-PPZ is superior to its polystyrene-based equivalent. SiliaBond Piperazine may also be used to scavenge electrophiles.
  4. SiliaBond Piperidine (PIP) (R71530B)

    SiliaBond Piperidine (PIP) (R71530B)

    SiliaBond Piperidine (Si-PIP) is a general purpose tertiary amine base to scavenge acids, thereby avoiding salt elimination problems. Also used as a base catalyst for Knoevenagel condensation.
  5. SiliaBond Amine (WAX) (R52030B)

    SiliaBond Amine (WAX) (R52030B)

    SiliaBond Amine (Si-NH2) is an effective scavenger of acid chlorides, sulfonyl chlorides, isocyanates and other electrophiles. Si-NH2 has been shown to be effective metal scavenger and catalyst for Knoevenagel reactions. SiliaBond Amine is also used in chromatography as normal phase sorbent.

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