SiliaBond & SiliaMetS Scavengers Selection Guide
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A quick overview of how our functionalized silica-based scavengers can improve & ease your synthesis, acting as metal/organic chelator to purify final mixtures contaminated by excess homogeneous reagent or metallic residue.
| Reaction | Scavenger |
|---|---|
| Acylation / Esterification | To remove metallic residues from homogeneous catalyst:
|
| Alkylation / Etherification | To remove metallic residues from homogeneous catalyst:
|
| Amide Coupling with acids, acid chlorides and amines | To remove excess acid chloride: To remove excess amine: |
| Amide Coupling Using HOBt | To remove excess homogeneous HOBt: |
| Catalytic Hydrogenation | To remove Pd: To remove Pt: To remove Ni: |
| Coupling Reactions (Buchwald Amination, Heck, Kumada, Negishi, Sonogashira, Stille & Suzuki Couplings and more...) |
To remove excess amine: To remove Pd: To remove Ni: To remove Cu: |
| Fmoc, Bsmoc Deprotection of Amino Acid | To remove excess FMOC-Cl or Bsmoc-Cl: |
| Grubbs Metathesis | To remove Ru: |
| Michael Addition | To remove Li: To remove Pd: |
| Nitro-Aldol (or Henry) Reaction | To remove Cu: |
| Reduction (Reductive Amination, Alkylation, etc.) |
To remove excess borohydride or excess amine: |
| Sharpless Dihydroxylation | To remove Os: |
| Sulfonamide Synthesis | To remove excess sulfonyl chloride: |
| Urea Synthesis | To remove excess isocyanate: |
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