- > Troubleshooting for Thin Layer Chromatography
- > Green Chemistry: Reduce Your Solvent Consumption and Waste Generation During Separations
- > How to Solve Common Challenges in Solid-Phase Extraction
- > How to Streamline Metal Scavenger Scale-Up During Drug Development
- > Thin Layer Chromatography Plates: Use and Best Practices
An AstraZeneca Case Study
> back to SiliaMetS Case Studies
In 2008, AstraZeneca published a paper in witch they removed palladium impurities in a large-scale process. The workup method that was found to work the best was a treatment with SiliaMetS Thiol (25 % w/w or ~1.4 kg) at 50°C to purify more than 6.7 kg. Final residual palladium concentration was as low as 1-2 ppm
Ryberg, P., Organic Process Research & Development, 2008, 12, 540
Process Chemistry, AstraZeneca PR&D, Sweden.
Process Chemistry, AstraZeneca PR&D, Sweden.
Read more
1 Item(s)
per page
List Grid
-
SiliaMetS Thiol (SH) Metal Scavenger (R51030B)
Our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh, Se & Sn.
1 Item(s)
per page
List Grid
Our Most Popular Categories
Our New Products
