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SiliaSep - Flash Cartridges

SiliCycle is the partner of choice
for your flash cartridges needs.

  • The use of pre-packed flash cartridges improves purification efficiency by offering superior reproducibility and productivity compared to conventional manual flash chromatography.
  • Pre-packed cartridges offer to chromatographers:
    • More tightly packed silica bed
    • Homogeneous packing
    • Better separation

SiliaSep - Flash Cartridges

SiliCycle supplies pre-packed columns offered under the brand name of SiliaSep Flash Cartridges.

SiliaSep cartridges are available in two silica gel grades (40-63 & 25 microns) and with various functionalities (reversed & normal phases, ion exchangers and metal scavengers) to meet any purification demand.

SiliaSep Flash Cartridge Overview

Our flash chromatography products offer high levels of performance and reproducibility. The flash media consistently has a tight particle size distribution with low fines and extremely low metal ion content, for more predictable and easier separations.

Using SiliCycle SiliaSep cartridges, you can purify your sample base on different mechanisms depending on the properties or your compound. Because we can provide cartridges packed with our SiliaBond® functionalized silica gel, you can choose exactly the cartridge that will fit your need.

> SiliaSep Features & Benefits

> SiliaSep Cartridges Characteristics

SiliaSep Flash Cartridge Design

SiliaSep Flash Cartridge design

SiliaSep Cartridges Compatibility

To better suits your needs, the SiliaSep flash cartridges family includes 5 types of cartridges that are compatible with different types of instruments:

Type Compatibility
SiliaSep Isco, Biotage, Analogix & Reveleris
SiliaSep XL Isco CombiFlash Companion XL.
Note: for SiliaSep XL cartridges (800g and 1600g), you will need an XL Adapter.
SiliaSep BT Biotage i
SiliaSep OT FlashMaster

SiliaSep Portfolio Overview

Type & Bed Weight Name Phases Use
  • 4 g
  • 12 g
  • 25 g
  • 40 g
  • 80 g
  • 120 g
  • 220 g
  • 330 g
  • 800 g
  • 1600 g
SiliaSep Normal Phases Normal phase chromatography is used to separate polar compounds through polar interactions with the support.
Reversed-Phases In reversed-phase chromatography, the packing material is always non-polar (hydrophobic) while the mobile phase is polar to non-polar. An important parameter affecting chromatographic efficiency is the hydrophobicity of the sorbent. As a general rule, stationary phase hydrophobicity increases with the alkyl chain length.
Ion Exchange Phases Ion exchange phases are widely used in separation and purification.
Metal Scavengers Lower the residual metal concentration of various metal complexes to single digit ppm. Any synthetic pathway is now possible, even the ones using metal catalysts.
BT (Biotage)
  • 200 g
  • 400 g
  • 800 g
SiliaSep BT 75 > phases available Designed to enhance your purifications when using the Biotage Flash 75 development-scale purification system.
OT (Open Top)
  • 2 g
  • 5 g
  • 10 g
  • 15 g
  • 20 g
  • 25 g
  • 50 g
  • 70 g
  • 100 g
SiliaSep OT > phases available Mainly used with vacuum manifolds and automated SPE equipments. Directly compatible with FlashMaster systems.

SiliaSep Accessories

We offer a range of accessories for your flash cartridges systems:

  • Pre-packed Solid-Load Cartridges (Silica, Amine, Diol, Cyano, C18)
  • Empty Solid-Load Cartridges
  • Plungers
  • Adapters, rings and conversion kits (for Biotage™ and FlashMaster™ systems)

> SiliaSep accessories