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Ion Exchange Phases

In ion exchange mode, the silica support is modified by a function carrying a charge with its counter-ion. This counter-ion is exchangeable with other ions in solution. If the immobilized phase is carrying an anion, the exchangeable species is a cation. Inversely, if the immobilized phase carries a cation, the ion exchangeable species will be an anion. Ion exchange phases are widely used in separation and purification.

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  1. SiliaSep Flash Cartridges, TMA Chloride (SAX) nec, 40 - 63 µm, 60 Å (FLH-R66530B)

    SiliaSep Flash Cartridges, TMA Chloride (SAX) nec, 40 - 63 µm, 60 Å (FLH-R66530B)

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by "catch and release" process.
  2. SiliaSep Flash Cartridges, TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (FLH-R66430B)

    SiliaSep Flash Cartridges, TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (FLH-R66430B)

    Packed with a strong anion exchanger, they can be used to fully retain acidic compounds for clean-up or to isolate them by "catch and release" process. The acetate counter-ion is easily exchangeable (more than the chloride ion).
  3. SiliaSep Flash Cartridges, Amine (WAX), 40 - 63 µm, 60 Å (FLH-R52030B)

    SiliaSep Flash Cartridges, Amine (WAX), 40 - 63 µm, 60 Å (FLH-R52030B)

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase. Also a weak anion exchanger, with a pKa of 9.8. At pH 7.8 or below, the functional groups are positively charged. It facilitates the rapid release of very strong anions such as sulfonic acids that may be too strongly retained on SAX.
  4. SiliaSep Flash Cartridges, Diamine, 40 - 63 µm, 60 Å (FLH-R49030B)

    SiliaSep Flash Cartridges, Diamine, 40 - 63 µm, 60 Å (FLH-R49030B)

    Well known for its electrophile scavenging efficiency and its base reagent quality, Diamine has also proven to be very useful for the scavenging of various metals.
  5. SiliaSep Flash Cartridges, Triamine, 40 - 63 µm, 60 Å (FLH-R48030B)

    SiliaSep Flash Cartridges, Triamine, 40 - 63 µm, 60 Å (FLH-R48030B)

    Well known for its electrophile scavenging efficiency and its base reagent quality, Triamine has also proven to be very useful for the scavenging of various metals. Best scavenger for: Cr, Pd, Pt, W & Zn. Good scavenger for: Ag, Cd, Co, Cu, Fe, Hg, Ni, Os, Pb, Rh, Ru & Sc.
  6. SiliaSep Flash Cartridges, WAX-2, 60 Å, 40 - 63 µm, 60 Å (FLH-R76530B)

    SiliaSep Flash Cartridges, WAX-2, 60 Å, 40 - 63 µm, 60 Å (FLH-R76530B)

    With a pKa of 10.5, this phase is preferred over SAX when performing catch and release purification of compounds bearing a permanent negative charge.
  7. SiliaSep Flash Cartridges,Tosic Acid (SCX), 40 - 63 µm, 60 Å (FLH-R60530B)

    SiliaSep Flash Cartridges,Tosic Acid (SCX), 40 - 63 µm, 60 Å (FLH-R60530B)

    Due to the very low pKa (< 1), Tosic Acid is a strong cation exchanger and maintains a negative charge throughout the pH scale. The most common use is likely for catch and release purification of weak cations.
  8. SiliaSep Flash Cartridges, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B)

    SiliaSep Flash Cartridges, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B)

    Due to the very low pKa (< 1), Propylsulfonic Acid is a strong cation exchanger and maintains a negative charge throughout the pH scale. The most common use is likely for catch and release purification of weak cations.
  9. SiliaSep Flash Cartridges, Bicarbonate, 40 - 63 µm, 60 Å (FLH-R65830B)

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