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SiliaSep - Flash Cartridges

SiliCycle is the partner of choice
for your flash cartridges needs.

  • The use of pre-packed flash cartridges improves purification efficiency by offering superior reproducibility and productivity compared to conventional manual flash chromatography.
  • Pre-packed cartridges offer to chromatographers:
    • More tightly packed silica bed
    • Homogeneous packing
    • Better separation

SiliaSep - Flash Cartridges

SiliCycle supplies pre-packed columns offered under the brand name of SiliaSep Flash Cartridges.

SiliaSep cartridges are available in two silica gel grades (40-63 & 25 microns) and with various functionalities (reversed & normal phases, ion exchangers and metal scavengers) to meet any purification demand.

SiliaSep Flash Cartridge Overview

Our flash chromatography products offer high levels of performance and reproducibility. The flash media consistently has a tight particle size distribution with low fines and extremely low metal ion content, for more predictable and easier separations.

Using SiliCycle SiliaSep cartridges, you can purify your sample base on different mechanisms depending on the properties or your compound. Because we can provide cartridges packed with our SiliaBond® functionalized silica gel, you can choose exactly the cartridge that will fit your need.

> SiliaSep Features & Benefits

> SiliaSep Cartridges Characteristics

SiliaSep Flash Cartridge Design

SiliaSep Flash Cartridge design

SiliaSep Cartridges Compatibility

To better suits your needs, the SiliaSep flash cartridges family includes 5 types of cartridges that are compatible with different types of instruments:

Type Compatibility
SiliaSep Isco, Biotage, Analogix & Reveleris
SiliaSep XL Isco CombiFlash Companion XL.
Note: for SiliaSep XL cartridges (800g and 1600g), you will need an XL Adapter.
SiliaSep BT Biotage i
SiliaSep OT FlashMaster

SiliaSep Portfolio Overview

Type & Bed Weight Name Phases Use
Universal
  • 4 g
  • 12 g
  • 25 g
  • 40 g
  • 80 g
  • 120 g
  • 220 g
  • 330 g
XL
  • 800 g
  • 1600 g
SiliaSep Normal Phases Normal phase chromatography is used to separate polar compounds through polar interactions with the support.
Reversed-Phases In reversed-phase chromatography, the packing material is always non-polar (hydrophobic) while the mobile phase is polar to non-polar. An important parameter affecting chromatographic efficiency is the hydrophobicity of the sorbent. As a general rule, stationary phase hydrophobicity increases with the alkyl chain length.
Ion Exchange Phases Ion exchange phases are widely used in separation and purification.
Metal Scavengers Lower the residual metal concentration of various metal complexes to single digit ppm. Any synthetic pathway is now possible, even the ones using metal catalysts.
BT (Biotage)
  • 200 g
  • 400 g
  • 800 g
SiliaSep BT 75 > phases available Designed to enhance your purifications when using the Biotage Flash 75 development-scale purification system.
OT (Open Top)
  • 2 g
  • 5 g
  • 10 g
  • 15 g
  • 20 g
  • 25 g
  • 50 g
  • 70 g
  • 100 g
SiliaSep OT > phases available Mainly used with vacuum manifolds and automated SPE equipments. Directly compatible with FlashMaster systems.

> SiliaSep accessories

44 Item(s)

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  1. SiliaSep Flash Cartridges, C18 (17%) monomeric, 40 - 63 µm, 60 Å (FLH-R33230B)

    SiliaSep Flash Cartridges, C18 (17%) monomeric, 40 - 63 µm, 60 Å (FLH-R33230B)

    Indicated for the purification of low to high polarity compounds. Provides reproducible purification without the complexity and cost of preparative HPLC.
  2. SiliaSep Flash Cartridges, Cyano (CN), 40 - 63 µm, 60 Å (FLH-R38030B)

    SiliaSep Flash Cartridges, Cyano (CN), 40 - 63 µm, 60 Å (FLH-R38030B)

    Versatile sorbent that can be used either as normal or reversed-phase. Indicated for products with intermediate to extreme polarity. The slightly hydrophobic nature of the cyano group offers alternative selectivity.
  3. SiliaSep Flash Cartridges, Amine (WAX), 40 - 63 µm, 60 Å (FLH-R52030B)

    SiliaSep Flash Cartridges, Amine (WAX), 40 - 63 µm, 60 Å (FLH-R52030B)

    Good alternative for normal phase purification of compounds with basic properties, which would normally have to be purified by reversed-phase. Also a weak anion exchanger, with a pKa of 9.8. At pH 7.8 or below, the functional groups are positively charged. It facilitates the rapid release of very strong anions such as sulfonic acids that may be too strongly retained on SAX.
  4. SiliaSep Flash Cartridges, Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B)

    SiliaSep Flash Cartridges, Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B)

    Good alternative for difficult separation of low to medium polarity samples. Useful for mono and polysaccharides separation. Can be used in HILIC mode.
  5. SiliaSep Flash Cartridges, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B)

    SiliaSep Flash Cartridges, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B)

    Due to the very low pKa (< 1), Propylsulfonic Acid is a strong cation exchanger and maintains a negative charge throughout the pH scale. The most common use is likely for catch and release purification of weak cations.
  6. SiliaSep Flash Cartridges, Triamine, 40 - 63 µm, 60 Å (FLH-R48030B)

    SiliaSep Flash Cartridges, Triamine, 40 - 63 µm, 60 Å (FLH-R48030B)

    Well known for its electrophile scavenging efficiency and its base reagent quality, Triamine has also proven to be very useful for the scavenging of various metals. Best scavenger for: Cr, Pd, Pt, W & Zn. Good scavenger for: Ag, Cd, Co, Cu, Fe, Hg, Ni, Os, Pb, Rh, Ru & Sc.
  7. SiliaSep Flash Cartridges, Diamine, 40 - 63 µm, 60 Å (FLH-R49030B)

    SiliaSep Flash Cartridges, Diamine, 40 - 63 µm, 60 Å (FLH-R49030B)

    Well known for its electrophile scavenging efficiency and its base reagent quality, Diamine has also proven to be very useful for the scavenging of various metals.
  8. SiliaSep Flash Cartridges, Thiol, 40 - 63 µm, 60 Å (FLH-R51030B)

    SiliaSep Flash Cartridges, Thiol, 40 - 63 µm, 60 Å (FLH-R51030B)

    Thiol is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh & Sn.
  9. SiliaSep Flash Cartridges, TAAcOH, 40 - 63 µm, 60 Å (FLH-R69030B)

    SiliaSep Flash Cartridges, TAAcOH, 40 - 63 µm, 60 Å (FLH-R69030B)

    TAAcOH is a silica bound metal scavenger for Pd0, Ni0 and Cu. It is the supported version of EDTA in its free form. It is an effective scavenger for metals in low or zero oxidation states, which includes many of the most synthetically useful catalysts. Best scavenger for: Ca, Co, Ir, Li, Mg, Ni, Os, Ru & Sc. Good scavenger for: Cr, Cs, Fe, Pd, Rh & Sn.
  10. SiliaSep Flash Cartridges, Cysteine, 40 - 63 µm, 60 Å (FLH-R80530B)

    SiliaSep Flash Cartridges, Cysteine, 40 - 63 µm, 60 Å (FLH-R80530B)

    Cysteine is the silica bound equivalent of the amino acid Cysteine. By attaching the molecule to the backbone via the amino group, the thiol group remains free and accessible for higher metal scavenging efficiency. It is a versatile metal scavenger for a variety of metals, under a wide range of conditions, and the preferred metal scavenger for tin residues. Best scavenger for: Cd, Fe, Ir, Os, Ru, Sc & Sn. Good scavenger for: Ca, Cr, Cs, Cu, La, Mg, Pd, Pt, Rh, Se & Zn.
  11. SiliaSep OT Flash Cartridges (Open Top), Silica, 40 - 63 µm, 60 Å (FLH-R10030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Silica, 40 - 63 µm, 60 Å (FLH-R10030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Most popular sorbent for day-to-day use for the purification of non-ionic polar organic compounds.
  12. SiliaSep OT Flash Cartridges (Open Top), Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B-OT)

    SiliaSep OT flash cartridges, compatible with any FlashMaster instrument. Good alternative for difficult separation of low to medium polarity samples. Useful for mono and polysaccharides separation. Can be used in HILIC mode.
  13. SiliaSep OT Flash Cartridges (Open Top), Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å

    SiliaSep OT Flash Cartridges (Open Top), Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å

    SiliaSep OT flash cartridges, compatible with any FlashMaster instrument. Strong cation exchangers since they maintain a negative charge throughout the pH scale. Most common use is likely for catch and release purification of weak cations, analysis of basic biomolecules and water-soluble vitamins
  14. SiliaSep OT Flash Cartridges (Open Top), Tosic Acid (SCX), 40 - 63 µm, 60 Å (FLH-R60530B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Tosic Acid (SCX), 40 - 63 µm, 60 Å (FLH-R60530B-OT)

    SiliaSep OT flash cartridges, compatible with any FlashMaster instrument. Strong cation exchangers since they maintain a negative charge throughout the pH scale. Most common use is likely for catch and release purification of weak cations, analysis of basic biomolecules and water-soluble vitamins
  15. SiliaSep OT Flash Cartridges (Open Top), TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (FLH-R66430B-OT)

    SiliaSep OT Flash Cartridges (Open Top), TMA Acetate (SAX-2) nec, 40 - 63 µm, 60 Å (FLH-R66430B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. The acetate counter-ion is easily exchangeable (more than the chloride ion) for compounds with pKa < 5, such as carboxylic acids. This phase can be used in organic chemistry applications to selectively purify acidic compounds or remove acidic impurities from reaction mixtures.
  16. SiliaSep OT Flash Cartridges (Open Top), Thiol, 40 - 63 µm, 60 Å (FLH-R51030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Thiol, 40 - 63 µm, 60 Å (FLH-R51030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Thiol is our most versatile and robust metal scavenger for a variety of metals under a wide range of conditions. Best scavenger for: Ag, Hg, Os, Pd & Ru. Good scavenger for: Cu, Ir, Pb, Rh & Sn
  17. SiliaSep BT Flash Cartridges, C18 (17%) monomeric, 40 - 63 µm, 60 Å (FLH-R33230B-BT)

    SiliaSep BT Flash Cartridges, C18 (17%) monomeric, 40 - 63 µm, 60 Å (FLH-R33230B-BT)

    Indicated for the purification of low to high polarity compounds. Provides reproducible purification without the complexity and cost of preparative HPLC. SiliaSep BT flash cartridges are compatible with Biotage™ i-style compression modules.
  18. SiliaSep BT Flash Cartridges, Cyano (CN), 40 - 63 µm, 60 Å (FLH-R38030B-BT)

    SiliaSep BT Flash Cartridges, Cyano (CN), 40 - 63 µm, 60 Å (FLH-R38030B-BT)

    Versatile sorbent that can be used either as normal or reversed-phase. Indicated for products with immediate to extreme polarity. The slightly hydrophobic nature of the cyano group offers alternative selectivity. SiliaSep BT flash cartridges are compatible with Biotage™ i-style compression modules.
  19. SiliaSep BT Flash Cartridges, Amine, 40 - 63 µm, 60 Å (FLH-R52030B-BT)

    SiliaSep BT Flash Cartridges, Amine, 40 - 63 µm, 60 Å (FLH-R52030B-BT)

    A weak anion exchanger with a pKa of 9.8. At pH 7.8 or below, the functional groups are positively charged. It facilitates the rapid release of very strong anions such as sulfonic acids that may be too strongly retained on SAX. SiliaSep BT flash cartridges are compatible with Biotage™ i-style compression modules.
  20. SiliaSep BT Flash Cartridges, Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B-BT)

    SiliaSep BT Flash Cartridges, Diol nec, 40 - 63 µm, 60 Å (FLH-R35030B-BT)

    Good alternative for difficult separation of low to medium polarity samples. Useful for mono and polysaccharides separation. Can be used in HILIC mode. SiliaSep BT flash cartridges are compatible with Biotage™ i-style compression modules.
  21. SiliaSep BT Flash Cartridges, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B-BT)

    SiliaSep BT Flash Cartridges, Propylsulfonic Acid (SCX-2), 40 - 63 µm, 60 Å (FLH-R51230B-BT)

    Due to its very low pKa (< 1) this strong cation exchanger maintains a negative charge throughout the pH scale. The most common use is likely for catch and release purification of weak cations (for example basic drugs and analgesics), analysis of basic biomolecules (peptides and proteins) and water-soluble vitamins (basic vitamins B and C). SiliaSep BT flash cartridges are compatible with Biotage™ i-style compression modules.
  22. SiliaSep Flash Cartridges, C18 Monomeric, 25 µm (FLH-03295D-A)
  23. SiliaSep Flash Cartridges, Silica, 25 µm (FLH-10095D-A)
  24. SiliaSep Flash Cartridges, Acidic Alumina, 50 - 200 µm, 60 Å (FLH-AUT-0053)

    SiliaSep Flash Cartridges, Acidic Alumina, 50 - 200 µm, 60 Å (FLH-AUT-0053)

    Good retention of aromatic compounds, aliphatic amines and compounds containing electronegative functions.
  25. SiliaSep Flash Cartridges, Neutral Alumina, 50 - 200 µm, 60 Å (FLH-AUT-0054)

    SiliaSep Flash Cartridges, Neutral Alumina, 50 - 200 µm, 60 Å (FLH-AUT-0054)

    Good retention of aromatic compounds, aliphatic amines and compounds containing electronegative functions.
  26. SiliaSep Flash Cartridges, Basic Alumina, 50 - 200 µm, 60 Å (FLH-AUT-0055)

    SiliaSep Flash Cartridges, Basic Alumina, 50 - 200 µm, 60 Å (FLH-AUT-0055)

    Good retention of aromatic compounds, aliphatic amines and compounds containing electronegative functions.
  27. SiliaSep Flash Cartridges, Silver Nitrate (AgNO3), 40 - 63 µm, 60 Å (FLH-R23530B)

    SiliaSep Flash Cartridges, Silver Nitrate (AgNO3), 40 - 63 µm, 60 Å (FLH-R23530B)

    Mainly used for the separation of cis / trans isomers of unsaturated compounds such as alkenes, lipids, steroids and terpenes.
  28. SiliaSep Flash Cartridges, C8 monomeric, 40 - 63 µm, 60 Å (FLH-R30830B)

    SiliaSep Flash Cartridges, C8 monomeric, 40 - 63 µm, 60 Å (FLH-R30830B)

    Presents less retention compared to C18. Typically used for highly hydrophobic pesticides, small peptides and large molecule drugs.
  29. SiliaSep Flash Cartridges, C8 nec, 40 - 63 µm, 60 Å (FLH-R31130B)

    SiliaSep Flash Cartridges, C8 nec, 40 - 63 µm, 60 Å (FLH-R31130B)

    Presents less retention compared to C18. Typically used for highly hydrophobic pesticides, small peptides and large molecule drugs.
  30. SiliaSep Flash Cartridges, C4, 40 - 63 µm, 60 Å (FLH-R32030B)

    SiliaSep Flash Cartridges, C4, 40 - 63 µm, 60 Å (FLH-R32030B)

    Presents less retention compared to C18 and C8. Widely used for molecules with large hydrophobic regions.
  31. SiliaSep Flash Cartridges, Phenyl, 40 - 63 µm, 60 Å (FLH-R34030B)

    SiliaSep Flash Cartridges, Phenyl, 40 - 63 µm, 60 Å (FLH-R34030B)

    Moderate non-polar sorbent with different selectivity for aromatic compounds compared to other non-polar sorbents.
  32. SiliaSep Flash Cartridges, Phenyl nec, 40 - 63 µm, 60 Å (FLH-R34130B)

    SiliaSep Flash Cartridges, Phenyl nec, 40 - 63 µm, 60 Å (FLH-R34130B)

    Moderate non-polar sorbent with different selectivity for aromatic compounds compared to other non-polar sorbents.
  33. SiliaSep Flash Cartridges, Pentafluorophenyl, 40 - 63 µm, 60 Å (FLH-R67530B)

    SiliaSep Flash Cartridges, Pentafluorophenyl (PFP), 40 - 63 µm, 60 Å (FLH-R67530B)

    For a new selectivity approach with aromatic ring interactions, or for the purification of conjugated compounds (isomers).
  34. SiliaSep Flash Cartridges, WAX-2, 60 Å, 40 - 63 µm, 60 Å (FLH-R76530B)

    SiliaSep Flash Cartridges, WAX-2, 60 Å, 40 - 63 µm, 60 Å (FLH-R76530B)

    With a pKa of 10.5, this phase is preferred over SAX when performing catch and release purification of compounds bearing a permanent negative charge.
  35. SiliaSep Flash Cartridges, Imidazole, 40 - 63 µm, 60 Å (FLH-R79230B)

    SiliaSep Flash Cartridges, Imidazole, 40 - 63 µm, 60 Å (FLH-R79230B)

    Imidazole is a versatile metal scavenger for a variety of metals, under a wide range of conditions, and the preferred metal scavenger for iron catalysts. Imidazole can also be used as an amine base in systems that are generally sensitive to basic conditions compared to other SiliaMetS supported bases. Best scavenger for: Cd, Co, Cu, Fe, Ir, Li, Mg, Ni, Os, W & Zn. Good scavenger for: Cr, Pd & Rh.
  36. SiliaSep OT Flash Cartridges (Open Top), TAAcOH, 25 mL, 40 - 63 µm, 60 Å (FLH-R69030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), TAAcOH, 40 - 63 µm, 60 Å (FLH-R69030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Ca, Co, Ir, Li, Mg, Ni, Os, Ru & Sc. Good scavenger for: Cr, Cs, Fe, Pd, Rh & Sn
  37. SiliaSep OT Flash Cartridges (Open Top), Cysteine, 40 - 63 µm, 60 Å (FLH-R80530B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Cysteine, 40 - 63 µm, 60 Å (FLH-R80530B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cd, Fe, Ir, Os, Ru, Sc & Sn. Good scavenger for: Ca, Cr, Cs, Cu, La, Mg, Pd, Pt, Rh, Se & Zn
  38. SiliaSep OT Flash Cartridges (Open Top), DMT, 40 - 63 µm, 60 Å (FLH-R79030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), DMT, 40 - 63 µm, 60 Å (FLH-R79030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Ir, Ni, Os, Pd, Pt, Rh, Se & Ru. Good scavenger for: Cd, Co, Cu, Fe, Sc & Zn
  39. SiliaSep OT Flash Cartridges (Open Top), Thiourea, 40 - 63 µm, 60 Å (FLH-R69530B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Thiourea, 40 - 63 µm, 60 Å (FLH-R69530B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Pd & Ru. Good scavenger for: Ag, Cu, Fe, Os, Rh, Sc & Sn.
  40. SiliaSep OT Flash Cartridges (Open Top), TAAcONa, 40 - 63 µm, 60 Å (FLH-R69230B-OT)

    SiliaSep OT Flash Cartridges (Open Top), TAAcONa, 40 - 63 µm, 60 Å (FLH-R69230B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Ca, Cd, Cs, Cu, Fe, Ir, La, Li, Mg, Ni, Os, Rh, Sc & Sn. Good scavenger for: Cr, Pd, Ru, Se & Zn.
  41. SiliaSep OT Flash Cartridges (Open Top), Imidazole, 40 - 63 µm, 60 Å (FLH-R79230B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Imidazole, 40 - 63 µm, 60 Å (FLH-R79230B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cd, Co, Cu, Fe, Ir, Li, Mg, Ni, Os, W & Zn. Good scavenger for: Cr, Pd & Rh.
  42. SiliaSep OT Flash Cartridges (Open Top), Triamine, 40 - 63 µm, 60 Å (FLH-R48030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Triamine, 40 - 63 µm, 60 Å (FLH-R48030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cr, Pd, Pt, W & Zn. Good scavenger for: Ag, Cd, Co, Cu, Fe, Hg, Ni, Os, Pb, Rh, Ru & Sc.
  43. SiliaSep OT Flash Cartridges (Open Top), Diamine, 40 - 63 µm, 60 Å (FLH-R49030B-OT)

    SiliaSep OT Flash Cartridges (Open Top), Diamine, 40 - 63 µm, 60 Å (FLH-R49030B-OT)

    SiliaSep OT flash cartridges, compatible with FlashMaster instrument. Best scavenger for: Cr, Pd, Pt, W & Zn. Good scavenger for: Cd, Co, Cu, Fe, Hg, Ni, Pb, Ru & Sc.
  44. SiliaSep Flash Cartridges, Diol, 25 µm, 90 Å (FLH-35095D-A)

    SiliaSep Flash Cartridges, Diol, 25 µm, 90 Å (FLH-35095D-A)

    Good alternative for difficult separation of low to medium polarity samples. Useful for mono and polysaccharides separation. Can be used in HILIC mode.

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